Abstract: The solid preparation which improved the dissolution profile and the stability of the 6,7-unsaturation-7-carbamoyl morphinan derivative is provided. When 6,7-unsaturation-7-carbamoyl morphinan derivative, croscarmellose sodium and ferric oxide were contained, not titanium oxide in the solid preparations and the coating solid preparations, a dissolution rate after 15 minutes of the dissolution test is more than 85%, and stability, particularly, light stability can be improve.

Abstract: The solid preparation which improved the dissolution profile and the stability of the 6,7-unsaturation-7-carbamoyl morphinan derivative is provided. When 6,7-unsaturation-7-carbamoyl morphinan derivative, croscarmellose sodium and ferric oxide were contained, not titanium oxide in the solid preparations and the coating solid preparations, a dissolution rate after 15 minutes of the dissolution test is more than 85%, and stability, particularly, light stability can be improve.

Abstract: The solid preparation which improved the dissolution profile and the stability of the 6,7-unsaturation-7-carbamoyl morphinan derivative is provided. When 6,7-unsaturation-7-carbamoyl morphinan derivative, croscarmellose sodium and ferric oxide were contained, not titanium oxide in the solid preparations and the coating solid preparations, a dissolution rate after 15 minutes of the dissolution test is more than 85%, and stability, particularly, light stability can be improve.

Abstract: The present invention provides a process for preparation of the compound of formula (VI), wherein each symbol is as defined in the specification, without using any intermediate compound showing mutagenicity. The process comprises salt formation of the intermediate compound of formula (I) with acid to enable optical resolution to isolate the intermediate compound of formula (II) in a stereo-selective manner.

Abstract: Stable crystalline forms of a compound represented by the formula (IA): an acid addition salt, and/or a solvate thereof are provided by the present invention. Said crystalline forms are extremely useful as materials for preparing medicines. Novel processes for preparing 6,7-unsaturated-7-carbamoyl morphinan derivatives are also provided by the present invention.

Abstract: Stable crystalline forms of a compound represented by the formula (IA): an acid addition salt, and/or a solvate thereof are provided by the present invention. Said crystalline forms are extremely useful as materials for preparing medicines. Novel processes for preparing 6,7-unsaturated-7-carbamoyl morphinan derivatives are also provided by the present invention.

Abstract: Stable crystalline forms of a compound represented by the formula (IA): , an acid addition salt, and/or a solvate thereof are provided by the present invention. Said crystalline forms are extremely useful as materials for preparing medicines. Novel processes for preparing 6,7-unsaturated-7-carbamoyl morphinan derivatives are also provided by the present invention.

Abstract: Stable crystalline forms of a compound represented by the formula (IA): an acid addition salt, and/or a solvate thereof are provided by the present invention. Said crystalline forms are extremely useful as materials for preparing medicines. Novel processes for preparing 6,7-unsaturated-7-carbamoyl morphinan derivatives are also provided by the present invention.

Abstract: Stable crystalline forms of a compound represented by the formula (IA): an acid addition salt, and/or a solvate thereof are provided by the present invention. Said crystalline forms are extremely useful as materials for preparing medicines. Novel processes for preparing 6,7-unsaturated-7-carbamoyl morphinan derivatives are also provided by the present invention.

Abstract: Stable crystalline forms of a compound represented by the formula (IA): an acid addition salt, and/or a solvate thereof are provided by the present invention. Said crystalline forms are extremely useful as materials for preparing medicines. Novel processes for preparing 6,7-unsaturated-7-carbamoyl morphinan derivatives are also provided by the present invention.

Abstract: An object of the invention is to provide a pressure-sensitive adhesive sheet. Provided is an acrylic polymer for use in a pressure-sensitive adhesive composition for a touch screen panel, the acrylic polymer being obtained by copolymerizing monomer components comprising (a) a (meth)acrylic acid ester monomer having a C1-12 hydrocarbon group, (b) a hydroxy group-containing (meth)acrylic acid ester monomer, (c) an amide group-containing monomer, and (d) a vinyl ester monomer. The acrylic polymer has an acid value of 0.1 mg KOH/g or less, a weight-average molecular weight of 400,000 to 2,000,000, a Tg of ?80 to 0° C., and a permittivity of 3 to 6.

Abstract: An object of the present invention is to provide a carbapenem synthetic intermediate which is advantageous in an industrial process. There are provided a process for producing Compound (I), or a pharmaceutically acceptable salt, or a solvate, or a crystal thereof, comprising reacting Compound (III) and Compound (IV) in the presence of the secondary amine, and a benzyl alcoholated crystal of Compound (I). There are further provided a method of deprotecting Compound (I) with a Pd catalyst, and a crystal of Compound (IV).

Abstract: A solution temperature control device in a biological cell observing chamber (30) used for the detection of chemotaxis and chemotactic cell separator, comprising a first temperature controller (62) and a second temperature controller (63). The first temperature controller (62) measures the temperature of a solution filled in a pair of wells and a flow passage in the chamber and controls the temperature to a specified temperature, and the second temperature controller (63) measures the temperature of a heating part (64) which heats the chamber (30) from the outside to indirectly heat the solution filled in the pair of wells and the flow passage and controls the temperature to a specified preheat temperature. Since the state and quantity of cells moving from one well to the other through the flow passage while holding the temperature of the solution at a specified temperature can be accurately observed and measured, accuracy for controlling the temperature of the solution can be remarkably increased.

Abstract: An object of the present invention is to provide a carbapenem synthetic intermediate which is advantageous in an industrial process. There are provided a process for producing Compound (I), or a pharmaceutically acceptable salt, or a solvate, or a crystal thereof, comprising reacting Compound (III) and Compound (IV) in the presence of the secondary amine, and a benzyl alcoholated crystal of Compound (I). There are further provided a method of deprotecting Compound (I) with a Pd catalyst, and a crystal of Compound (IV).

Abstract: A solution temperature control device in a biological cell observing chamber (30) used for the detection of chemotaxis and chemotactic cell separator, comprising a first temperature controller (62) and a second temperature controller (63). The first temperature controller (62) measures the temperature of a solution filled in a pair of wells and a flow passage in the chamber and controls the temperature to a specified temperature, and the second temperature controller (63) measures the temperature of a heating part (64) which heats the chamber (30) from the outside to indirectly heat the solution filled in the pair of wells and the flow passage and controls the temperature to a specified preheat temperature. Since the state and quantity of cells moving from one well to the other through the flow passage while holding the temperature of the solution at a specified temperature can be accurately observed and measured, accuracy for controlling the temperature of the solution can be remarkably increased.

Abstract: To provide a wristwatch type wireless telephone improved in terms of handling in that there is no need to change the holding state of the wristwatch type wireless telephone when the wristwatch type wireless telephone is used for telephone conversation by being removed from an arm and held in a hand. In a wristwatch type wireless telephone carried by being worn on an arm by binding with an arm band, a sound radiating hole of a mouthpiece and a sound receiving hole of an ear piece are formed in a surface at a back surface, at the arm side in a state of being worn on an arm.

Abstract: To provide electronic device, which is easily assembled and disassembled. A cup-shaped introduction tube made of a rubber type member is inserted in an introduction hole provided in a watch case. On an outer peripheral surface of the introduction tube, a convex portion having a uniform semi-arch shape in cross-section in an axial direction is integrally formed. A metal pipe is inserted into the introduction tube, and an outer diameter of the metal pipe and an inner diameter of the introduction tube have a relationship of close fit before insertion. Furthermore, at an end portion of the metal pipe, a brim-shaped edge portion is formed. A ring groove is formed on a cup bottom surface of the introduction tube. In the ring groove, an annular O-ring made of a rubber type member is sandwiched. The O-ring has substantially the same inner diameter as the diameter of a shield line, and the O-ring forms a seal surface among the shield line, the metal pipe, and the ring groove in a crushed state.

Abstract: To provide electronic device, which is easily assembled and disassembled. A cup-shaped introduction tube made of a rubber type member is inserted in an introduction hole provided in a watch case. On an outer peripheral surface of the introduction tube, a convex portion having a uniform semi-arch shape in cross-section in an axial direction is integrally formed. A metal pipe is inserted into the introduction tube, and an outer diameter of the metal pipe and an inner diameter of the introduction tube have a relationship of close fit before insertion. Furthermore, at an end portion of the metal pipe, a brim-shaped edge portion is formed. A ring groove is formed on a cup bottom surface of the introduction tube. In the ring groove, an annular O-ring made of a rubber type member is sandwiched. The O-ring has substantially the same inner diameter as the diameter of a shield line, and the O-ring forms a seal surface among the shield line, the metal pipe, and the ring groove in a crushed state.

Abstract: A water-resistant function can be maintained even in the case where a substrate is interposed between packings. Packing has a rib-shaped convex portion having a uniform height and width on a surface contacting a flexible substrate. The packing with such a convex portion is fitted in grooves provided in a body and a back cover. The rib-shaped convex portion disposed on the packing is biased to an edge portion of the substrate when a housing is closed, and is elastically deformed in a direction in which it comes into close contact with a side surface portion of the substrate. Thus, the convex portion disposed on the packing blocks up a gap generated in the vicinity of the side surface of the substrate and has a functional effect of suppressing water from entering.

Abstract: To provide a wristwatch type wireless telephone improved in terms of handling in that there is no need to change the holding state of the wristwatch type wireless telephone when the wristwatch type wireless telephone is used for telephone conversation by being removed from an arm and held in a hand. In a wristwatch type wireless telephone carried by being worn on an arm by binding with an arm band, a sound radiating hole of a mouthpiece and a sound receiving hole of an ear piece are formed in a surface at a back surface, at the arm side in a state of being worn on an arm.