Abstract: A thienotriazolodiazepine compound of the following formula (I) a pharmaceutical agent containing the compound as an active ingredient, and a production intermediate and a production method of the thienotriazolodiazepine compound. Since this compound has an inhibitory action on costimulatory signal from CD28 on T cell, it is useful for the prophylaxis or suppression of rejection reaction in transplantation of organ or bone marrow and the like, and the prophylaxis or treatment of autoimmune diseases or allergic diseases.

Abstract: [Solving means] A thienotriazolodiazepine compound of the following formula (I) a pharmaceutical agent containing the compound as an active ingredient, and a production intermediate and a production method of the thienotriazolodiazepine compound. [Effect]Since this compound has an inhibitory action on costimulatory signal from CD28 on T cell, it is useful for the prophylaxis or suppression of rejection reaction in transplantation of organ or bone marrow and the like, and the prophylaxis or treatment of autoimmune diseases or allergic diseases.

Abstract: The object is to provide an optical system with a wavelength selecting device. According to one aspect of the present invention, an optical system with a wavelength selecting device includes, in order from an object along an optical axis, an objective optical system composed of optical elements having refractive power and an aperture stop, a no-power optical group composed of optical elements having no refractive power, and an imaging device. The no-power optical group includes the wavelength selecting device for making short wavelength light be selectively substantially non-transparent. The wavelength selecting device preferably satisfies the predetermined conditional expressions.

Abstract: When used concurrently with an antitumor agent, a compound having a Rho kinase inhibitory activity, such as (R)-(+)-N-(4-pyridyl)-4-(1-aminoethyl)benzamide, reinforces an antitumor effect of the antitumor agent and is useful as an antitumor effect potentiator. Particularly, a compound having a Rho kinase inhibitory activity used with an antitumor agent in combination can reduce the dose of the antitumor agent, which in turn affords provision of a sufficient effect and/or reduction of side effects.

Abstract: When used concurrently with an antitumor agent, a compound having a Rho kinase inhibitory activity, such as (R)-(+)-N-(4-pyridyl)-4-(1-aminoethyl)benzamide, reinforces an antitumor effect of the antitumor agent and is useful as an antitumor effect potentiator.

Abstract: In order to provide an eyepiece lens which has a sufficiently long eye relief and a high magnification, there is provided an eyepiece lens for observing an image formed by an objective lens through an erect system, at least comprising a first lens group 4 having a positive refracting power and a second lens group 3 having a negative refracting power in this order from the side of an observer, and satisfying the following condition: −3<SF1<−1  (1) where SF1 indicates a shape factor of the first lens group 4, and SF indicates a shape factor of the lens group, which is defined by: SF=(Rs+RE)/(Rs−RE), where Rs indicates a radius of curvature of a lens surface which is closest to the object side and RE indicates a radius of curvature of a lens surface which is closest to the observer side.

Abstract: In order to provide an eyepiece lens which has a sufficiently long eye relief and a high magnification, there is provided an eyepiece lens for observing an image formed by an objective lens through an erect system, at least comprising a first lens group 4 having a positive refracting power and a second lens group 3 having a negative refracting power in this order from the side of an observer, and satisfying the following condition:

Abstract: A variable focal length lens system with low cost, suitable for use with a video camera or a digital still camera employing a solid-state imaging device, capable of assembling and adjusting with ease, and to provide an imaging apparatus equipped with the lens system is provided.