Patents by Inventor Kouichi Ushimaru

Kouichi Ushimaru has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 5635491
    Abstract: A lyophilized preparation which releases a fat emulsion, wherein the emulsion particle has a mean diameter of 10 to 100 nm, when redissolved prior to use. This preparation is produced by adding maltose in an arbitrary stage of the production of said emulsion prior to lyophilization.
    Type: Grant
    Filed: June 21, 1993
    Date of Patent: June 3, 1997
    Assignee: Nippon Shinyaku Co., Ltd.
    Inventors: Junzo Seki, Hirofumi Yamamoto, Shuji Yamane, Yutaka Takahashi, Kouichi Ushimaru
  • Patent number: 5534502
    Abstract: Stable homogeneous fatty emulsions containing amphotericin B are prepared. According to one embodiment, amphotericin B is decrystallized using an acid and ethanol and then homogeneously dispersed in a lipid, following which it is emulsified.According to a second embodiment, amphotericin B crystals are kneaded until their presence can no longer be confirmed and the decrystallized amphotericin B is thereafter uniformly dispersed in a lipid and, thereafter, emulsified.
    Type: Grant
    Filed: April 7, 1995
    Date of Patent: July 9, 1996
    Assignee: Nippon Shinyaku Co. Ltd.
    Inventors: Junzo Seki, Hirofumi Yamamoto, Shuji Yamane, Yutaka Takahashi, Kouichi Ushimaru
  • Patent number: 5368861
    Abstract: A gastric preparation developed in order to solve the technical problems of conventional preparations, which is prepared by the bilayer packing technique and comprises 5 to 60%, desirably 10 to 40% of a rapid release portion which can establish the therapeutic level of a drug shortly after the administration and 95 to 40%, desirably 90 to 60% of a sustained release portion which has a specific gravity or 1 or less and can maintain a satisfactory release rate.
    Type: Grant
    Filed: April 24, 1992
    Date of Patent: November 29, 1994
    Assignee: Nippon Shinyaku Co., Ltd.
    Inventors: Kouichi Ushimaru, Kouichi Nakamichi, Hiroyuki Yasuura