Patents by Inventor Kouichirou YORI

Kouichirou YORI has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20200393482
    Abstract: Disclosed are a cell processing method, a device, and a robot system that has a simple constitution and are reasonable. A robot system is provided for injecting liquid by rotating an injection container containing the liquid and an injection volume of the liquid is constant around an axis vertical to a long axis of the injection container. The robot system executes an injection start control to rotate the injection container around a predetermined axis, an injection control to stop rotation for a predetermined time and inject the liquid, and an injection end control to reversely rotate the injection container around the predetermined axis, and the predetermined time is calculated based on an injection flow rate measured in real time.
    Type: Application
    Filed: August 31, 2020
    Publication date: December 17, 2020
    Applicant: TERUMO KABUSHIKI KAISHA
    Inventors: Makoto JINNO, Ryosuke NONOYAMA, Kouichirou YORI, Tadashi SAMESHIMA
  • Patent number: 10806139
    Abstract: A method is disclosed for recovering living cells highly efficiently from cryopreserved cells by thawing and a system designed for such a method. The method for recovering living cells from cryopreserved cells includes thawing cryopreserved cells and diluting the thawed cell suspension with a diluent, wherein the dilution is performed in such a way that the maximum load of osmotic pressure at the time of dilution is equal to or less than 250 mOsm/second.
    Type: Grant
    Filed: September 23, 2016
    Date of Patent: October 20, 2020
    Assignee: TERUMO KABUSHIKI KAISHA
    Inventors: Kouichirou Yori, Ryohei Takeuchi
  • Patent number: 10787633
    Abstract: A liquid transport method is disclosed for efficiently producing cell cultures. The liquid transport method of the present disclosure, which is in processing of cells, includes: a) a step in which a container holding a liquid is gripped by a gripping tool of a robot; and b) a step in which the liquid in the container is transported to a collection container by rotating the gripped container. In steps a) and b) the robot operates such as not to pass over a vertical line of an opening of the collection container.
    Type: Grant
    Filed: June 26, 2017
    Date of Patent: September 29, 2020
    Assignee: TERUMO KABUSHIKI KAISHA
    Inventors: Kouichirou Yori, Makoto Jinno
  • Publication number: 20200255779
    Abstract: A liquid transport method is disclosed for efficiently producing cell cultures. The liquid transport method of the present disclosure, which is in processing of cells, includes: a) a step in which a container holding a liquid is gripped by a gripping tool of a robot; and b) a step in which the liquid in the container is transported to a collection container by rotating the gripped container. In steps a) and b) the robot operates such as not to pass over a vertical line of an opening of the collection container.
    Type: Application
    Filed: April 30, 2020
    Publication date: August 13, 2020
    Applicant: TERUMO KABUSHIKI KAISHA
    Inventors: Kouichirou YORI, Makoto JINNO
  • Patent number: 10426802
    Abstract: A sheet-shaped cell culture and method for producing a sheet-shaped cell culture are disclosed having a high activity such as high cytokine productivity and a production method thereof. The method for producing a sheet-shaped cell culture can include freezing cells, thawing the frozen cells and forming a sheet-shaped cell culture. A sheet-shaped cell culture which is produced by the production method and which has a high activity and a method for treating a disease associated with an abnormality of a tissue with the sheet-shaped cell culture.
    Type: Grant
    Filed: November 17, 2015
    Date of Patent: October 1, 2019
    Assignee: TERUMO KABUSHIKI KAISHA
    Inventors: Kenta Sakamoto, Kouichirou Yori
  • Publication number: 20190236784
    Abstract: [Problem] To evaluate objective cell groups by estimating a mixing ratio of objective cell group without affecting treatment itself and its production process when the objective cell groups include plural kinds of cell groups having different attributes, and to provide an image analysis system and a culture management system capable of accurately perform a quality control and a production control with low cost. [Solution] The cell quality evaluation system 1 detects a feature amount in each cell easily analyzable from images, and estimates a mixing ratio of each of plural kinds of cell groups included in the objective cell groups based on a distribution of the detected feature amount and pre-recorded information of the feature amount. As the feature amount, the embodiment uses a migration speed of each cell, easily distinguishable by analyzing tracking of each cell from plural images in time series.
    Type: Application
    Filed: July 13, 2017
    Publication date: August 1, 2019
    Inventors: Ryoma BISE, Yoshitaka MAEDA, Masatoshi KURODA, Kazumasa YAMAKI, Ryohei TAKEUCHI, Fumiya OHASHI, Kouichirou YORI
  • Publication number: 20190021706
    Abstract: A tissue collection device including a sheath member that has a first threaded portion on the inner surface of the sheath member and a puncture tube positionable in the interior of the sheath member. The puncture tube is axially movable in distal and proximal directions relative to the sheath member. The puncture tube has a second threaded portion on the outer surface of the puncture tube that threadedly engages with the first threaded portion when the puncture tube is within the interior of the sheath member. At least one of the distal end of the sheath member and the distal end of the puncture tube includes a blade to incise tissue from a living body.
    Type: Application
    Filed: September 21, 2018
    Publication date: January 24, 2019
    Applicant: TERUMO KABUSHIKI KAISHA
    Inventor: Kouichirou YORI
  • Publication number: 20190017006
    Abstract: A method, a device, and an annular member are disclosed for keeping a shape of a fragile material in a liquid in a container. The method includes covering a surface of the liquid with a sealing material configured to melt and solidify according to a temperature change; and solidifying the sealing material to cover the surface of the liquid. The device includes a container configured to hold the fragile material; and a sealing material configured to melt and solidify according to a temperature change. The annular member includes an upper annular groove configured to receive a sealing material, the sealing material configured to melt and solidify according to a temperature change, the upper annular groove having an inner wall and an outer wall, and wherein a height of the inner wall is lower than a height of the outer wall.
    Type: Application
    Filed: September 20, 2018
    Publication date: January 17, 2019
    Applicant: TERUMO KABUSHIKI KAISHA
    Inventors: Ryohei TAKEUCHI, Minori KIKUCHI, Eri NOGUCHI, Kouichirou YORI
  • Publication number: 20180067099
    Abstract: A method for evaluating the ability of cells to grow into a sheet includes (1) a step of examining cell cultures growing into a sheet to determine their impedance and/or electrical resistance or numerical values relating thereto; (2) a step of comparing the numerical values determined by Step (1) with reference values; and (3) a step of judging, based on the results of comparison obtained in Step (2), the ability of cells to grow into a sheet.
    Type: Application
    Filed: September 27, 2017
    Publication date: March 8, 2018
    Applicant: TERUMO KABUSHIKI KAISHA
    Inventors: Ryohei TAKEUCHI, Kouichirou YORI
  • Patent number: 9895522
    Abstract: A cell culture transferring instrument includes a cylindrical body held by an operator not shown in the drawing, a plunger inserted through the interior of the cylindrical body, a plurality of support members connected to a distal end of the plunger, and an adsorbent capable of adsorbing a sheet-shaped cell culture held by the support members. The support members in contact with the distal end of the cylindrical body are elastically deformed by displacing the plunger toward the proximal end side with respect to the cylindrical body in a state in which the sheet-shaped cell culture is adsorbed to the adsorbent, whereby the adsorbent and the sheet-shaped cell culture are deformed and housed in a housing hole in the cylindrical body.
    Type: Grant
    Filed: June 19, 2014
    Date of Patent: February 20, 2018
    Assignee: TERUMO KABUSHIKI KAISHA
    Inventor: Kouichirou Yori
  • Publication number: 20170292101
    Abstract: A liquid transport method is disclosed for efficiently producing cell cultures. The liquid transport method of the present disclosure, which is in processing of cells, includes: a) a step in which a container holding a liquid is gripped by a gripping tool of a robot; and b) a step in which the liquid in the container is transported to a collection container by rotating the gripped container. In steps a) and b) the robot operates such as not to pass over a vertical line of an opening of the collection container.
    Type: Application
    Filed: June 26, 2017
    Publication date: October 12, 2017
    Applicant: TERUMO KABUSHIKI KAISHA
    Inventors: Kouichirou YORI, Makoto JINNO
  • Publication number: 20170273773
    Abstract: A medical device is disclosed, which is capable of treating cardiac insufficiency, on a causal therapy basis. The medical device is a heart harness composed of a porous hollow structure. A method of treating a heart disease includes applying the medical device as above to a heart of a subject in need thereof.
    Type: Application
    Filed: March 27, 2017
    Publication date: September 28, 2017
    Applicant: TERUMO KABUSHIKI KAISHA
    Inventor: Kouichirou YORI
  • Publication number: 20170006857
    Abstract: A method is disclosed for recovering living cells highly efficiently from cryopreserved cells by thawing and a system designed for such a method. The method for recovering living cells from cryopreserved cells includes thawing cryopreserved cells and diluting the thawed cell suspension with a diluent, wherein the dilution is performed in such a way that the maximum load of osmotic pressure at the time of dilution is equal to or less than 250 mOsm/second.
    Type: Application
    Filed: September 23, 2016
    Publication date: January 12, 2017
    Applicant: TERUMO KABUSHIKI KAISHA
    Inventors: Kouichirou YORI, Ryohei TAKEUCHI
  • Publication number: 20160067284
    Abstract: A sheet-shaped cell culture and method for producing a sheet-shaped cell culture are disclosed having a high activity such as high cytokine productivity and a production method thereof. The method for producing a sheet-shaped cell culture can include freezing cells, thawing the frozen cells and forming a sheet-shaped cell culture. A sheet-shaped cell culture which is produced by the production method and which has a high activity and a method for treating a disease associated with an abnormality of a tissue with the sheet-shaped cell culture.
    Type: Application
    Filed: November 17, 2015
    Publication date: March 10, 2016
    Applicant: TERUMO KABUSHIKI KAISHA
    Inventors: Kenta SAKAMOTO, Kouichirou YORI
  • Publication number: 20140303598
    Abstract: A cell culture transferring instrument includes a cylindrical body held by an operator not shown in the drawing, a plunger inserted through the interior of the cylindrical body, a plurality of support members connected to a distal end of the plunger, and an adsorbent capable of adsorbing a sheet-shaped cell culture held by the support members. The support members in contact with the distal end of the cylindrical body are elastically deformed by displacing the plunger toward the proximal end side with respect to the cylindrical body in a state in which the sheet-shaped cell culture is adsorbed to the adsorbent, whereby the adsorbent and the sheet-shaped cell culture are deformed and housed in a housing hole in the cylindrical body.
    Type: Application
    Filed: June 19, 2014
    Publication date: October 9, 2014
    Inventor: Kouichirou YORI