Abstract: A pressure sensor has a stem in which a pressure introduction hole into which a pressure medium is introduced and a diaphragm deformable according to the pressure of the pressure medium are formed, and a strain detecting element which is arranged on the diaphragm via an insulating film and being configured to output a detection signal according to the deformation of the diaphragm. The strain detecting element is configured to have a portion made of polysilicon. A low doping layer having a higher electrical resistivity than polysilicon and a higher crystallinity than the insulating film is arranged between the insulating film and the strain detecting element.

Abstract: A method for producing an isocyanate, comprising: a carbamation step of generating an N-substituted carbamate from an organic primary amine, urea and an organic hydroxy compound according to a carbamation reaction, and then recovering a first gaseous phase component containing the urea and/or a compound having a carbonyl group derived from the urea, the organic hydroxy compound, and ammonia; a condensation step of condensing the first gaseous phase component with a condenser; an isocyanate production step of producing an isocyanate by subjecting the N-substituted carbamate to pyrolysis; an ammonia absorption step of allowing a second gaseous phase component containing ammonia recovered as a gaseous phase component from the condenser as a main component, to be absorbed by absorption water, and generating gas-absorbed water; and an ammonia stripping step of heating the gas-absorbed water to separate ammonia from the gas-absorbed water.

Abstract: A method for producing an isocyanate, comprising: a carbamation step of generating an N-substituted carbamate from an organic primary amine, urea and an organic hydroxy compound according to a carbamation reaction, and then recovering a first gaseous phase component containing the urea and/or a compound having a carbonyl group derived from the urea, the organic hydroxy compound, and ammonia; a condensation step of condensing the first gaseous phase component with a condenser; an isocyanate production step of producing an isocyanate by subjecting the N-substituted carbamate to pyrolysis; an ammonia absorption step of allowing a second gaseous phase component containing ammonia recovered as a gaseous phase component from the condenser as a main component, to be absorbed by absorption water, and generating gas-absorbed water; and an ammonia stripping step of heating the gas-absorbed water to separate ammonia from the gas-absorbed water.

Abstract: A wiper device includes pivot shafts to which wiper arms are secured, pivot holders, which rotationally support the pivot shafts, coupling shafts, and a pipe frame having cylindrical ends. The cylindrical ends of the pipe frame are coupled to the coupling shafts. The coupling shafts each include a swaging part, which is swaged to the corresponding cylindrical end, and a flat portion, which is located at part of the coupling shaft exposed from the pipe frame. The flat portions have a predetermined angle with respect to the swaging direction of the swaging and are parallel to the axis of the coupling shafts.

Abstract: A wiper device includes pivot shafts to which wiper arms are secured, pivot holders, which rotationally support the pivot shafts, coupling shafts, and a pipe frame having cylindrical ends. The cylindrical ends of the pipe frame are coupled to the coupling shafts. The coupling shafts each include a swaging part, which is swaged to the corresponding cylindrical end, and a flat portion, which is located at part of the coupling shaft exposed from the pipe frame. The flat portions have a predetermined angle with respect to the swaging direction of the swaging and are parallel to the axis of the coupling shafts.

Abstract: To provide a pharmaceutical composition comprising a ceramide-related substance having little adverse side effects as an active ingredient by using a raw material that is highly safe to a human body and is inexpensive. A pharmaceutical composition comprising at least one sphingoglycolipid derivative that is produced from a beer waste and is represented by the formula below as an active ingredient: wherein R3 represents H or OH; R4 is as defined by (a) or (b) (a) when R3 is H, R4 represents (CH2)13CH3 or (CH2)6CH?CHCH2CH?CH(CH2)4CH3; and (b) when R3 is OH, R4 represents (CH2)yCH3 (where Y represents an integer of 13 to 21) or (CH2)Z1CH?CH(CH2)Z2CH3 (where Z1 and Z2 independently represent 0 or a natural number, provided that Z1+Z2=19).

Abstract: A method for producing a molded product consisting of a resin polymerized by a melt polycondensation reaction, comprising continuous feeding of a prepolymer in molten state from a prepolymer feeding port to a polymerization reactor, discharging from holes of a porous plate, followed by polymerization while dropping along a supporting substrate under reduced pressure, and molding by transferring to at least one molding machine in molten state without solidification, wherein transfer pressure to said molding machine is controlled so as to maintain at an arbitrary pressure from 0.1 to 100 MPa (absolute pressure).

Abstract: To provide a pharmaceutical composition comprising a ceramide-related substance having little adverse side effects as an active ingredient by using a raw material that is highly safe to a human body and is inexpensive. A pharmaceutical composition comprising at least one sphingoglycolipid derivative that is produced from a beer waste and is represented by the formula below as an active ingredient: wherein R3 represents H or OH; R4 is as defined by (a) or (b): (a) when R3 is H, R4 represents (CH2)13CH3 or (CH2)6CH?CHCH2CH?CH(CH2)4CH3; and (b) when R3 is OH, R4 represents (CH2)yCH3 (where Y represents an integer of 13 to 21) or (CH2)z1CH?CH(CH2)Z2CH3 (where Z1 and Z2 independently represent 0 or a natural number, provided that Z1+Z2=19).

Abstract: A method for producing a molded product consisting of a resin polymerized by a melt polycondensation reaction, comprising continuous feeding of a prepolymer in molten state from a prepolymer feeding port to a polymerization reactor, discharging from holes of a porous plate, followed by polymerization while dropping along a supporting substrate under reduced pressure, and molding by transferring to at least one molding machine in molten state without solidification, wherein transfer pressure to said molding machine is controlled so as to maintain at an arbitrary pressure from 0.1 to 100 MPa (absolute pressure).

Abstract: Stable, long-term cultures of animal cells are accomplished by calculating the ratio of lactic acid formed by the cells to the glucose consumed by the cells (the L/G ratio) and controlling the cultivation conditions to maintain the L/G ratio between the limits of from greater than 0 to 0.6. When the ratio is outside the desired range, the dissolved oxygen concentration in the medium is increased and/or the glucose concentration in the medium is decreased.

Abstract: By culturing cells in an apparatus containing a first zone in which a cell suspended medium is present and a second zone in which liquid containing a physiological saline solution and/or nutrient sources is present, the first zone being separated from the second zone by a septum with characteristics, such as pores size or electrostatic charges, which impedes the cells from freely permeating through, while allowing at least one of nutrient sources, cell wastes or the product to move between the first zone and the second zone via the septum to proliferate cells in the first zone, wherein a flow rate via the septum is controlled in such a manner that the cell count moved from the first zone into the second zone via the septum does not exceed the cell count increased by cell growth in the first zone. Thus, cell culture at a high cell density can be achieved in a large scale.

Abstract: A molten material is prepared by heating a mixture of (A) a polyhydric alcohol containing a neopentyl structure such as pentaerythritol, dipentaerythritol or tripentaerythritol which is less compatible with a halogen-containing resin and (B) a partial ester of said polyhydric alcohol and a carboxyl group-containing compound which has good compatibility with the halogen-containing resin to the molten state. The molten material functions as a stabilizer assistant which markedly increases the thermal stabilizing effect of divalent metal stabilizers for the halogen-containing resin.