Abstract: Carrier polymer particles comprising organic polymer particles having a particle diameter of 0.1 to 20 micrometers and a saccharide with which the surface of the organic polymer particles is covered, the organic polymer particles and the saccharide being chemically bonded.

Abstract: Provided is a filler for affinity chromatography having a high dynamic binding capacity for proteins and having excellent alkali resistance and storage stability. The filler for affinity chromatography of the present invention comprises a porous particle consisting of a copolymer of 40 parts to 99.5 parts by mass of (M-1) a methacryloyl group-containing vinyl monomer that contains a hydroxyl group and does not contain an epoxy group, 0.5 parts to 30 parts by mass of (M-2) an epoxy group-containing vinyl monomer, 0 parts to 59.5 parts by mass of (M-3) a methacryloyl group-containing vinyl monomer which is other than the monomers (M-1) and (M-2), and 0 parts to 25 parts by mass of (M-4) a vinyl monomer other than the monomers (M-1), (M-2) and (M-3) (with the proviso that the total amount of the contents of (M-1), (M-2), (M-3) and (M-4) is 100 parts by mass); ring-opened epoxy group obtainable by ring-opening of epoxy group that is contained in the copolymer; and ligand that is bound to the porous particle.

Abstract: A non-specific adsorption inhibitor of formula (1), wherein n is a real number of 4 to 2,000, R1 and R2 individually represent a hydrogen atom or a group comprising 1 to 11 amino group(s) or imino group(s), or both, provided that the total number of amino groups and imino groups contained in R1 and R2 is 2 to 11. Non-specific adsorption inhibitor composition, probe-bonded particles.

Abstract: Provided are a filler for affinity chromatography which has excellent alkali resistance, and a method for isolating immunoglobulin. The filler for affinity chromatography is a filler in which a protein represented by the following formula (1) is immobilized on a carrier. R—R2 ??(1) wherein R represents an amino acid sequence consisting of 4 to 300 amino acid residues containing a region consisting of 4 to 20 contiguous histidine residues; and R2 represents an amino acid sequence capable of binding to immunoglobulin, the amino acid sequence consisting of 50 to 500 amino acid residues containing Z domain of Protein A or a fragment thereof, or a variant thereof, provided that the R binds to C-terminus or N-terminus of the R2.

Abstract: Provided is a filler for affinity chromatography which is useful for protein purification and contains porous particles that have a high dynamic binding capacity for proteins and excellent pressure characteristics. The filler for affinity chromatography of the present invention is characterized in that it includes a porous particle consisting of a polymer of vinyl monomer including a cross-linkable vinyl monomer that contains hydroxyl group but does not contain epoxy group and an epoxy group-containing non-cross-linkable vinyl monomer, or a cross-linkable vinyl monomer that contains hydroxyl group and epoxy group, ligands bound to the porous particle, and ring-opened epoxy groups.

Abstract: A non-specific adsorption inhibitor of formula (1), wherein n is a real number of 4 to 2,000, R1 and R2 individually represent a hydrogen atom or a group comprising 1 to 11 amino group(s) or imino group(s), or both, provided that the total number of amino groups and imino groups contained in R1 and R2 is 2 to 11. Non-specific adsorption inhibitor composition, probe-bonded particles.

Abstract: An affinity chromatography packing material includes porous mother particles that include a copolymer of a monomer mixture including a crosslinkable vinyl monomer and an epoxy group-containing vinyl monomer, a ligand being bound to the porous mother particles, and the porous mother particles including a ring-opening epoxy group produced by ring-opening of the epoxy group included in the porous mother particles.

Abstract: Organic polymer particles having a structure shown by the following formula (1) are disclosed. wherein A represents an alkylidene group, an alkylene group, a cyclohexylene group, or a phenylene group, and B represents a linear or branched alkylene group or an alkylidene group having 1 to 6 carbon atoms.

Abstract: Carrier polymer particles comprising organic polymer particles having a particle diameter of 0.1 to 20 micrometers and a saccharide with which the surface of the organic polymer particles is covered, the organic polymer particles and the saccharide being chemically bonded.

Abstract: Organic polymer particles having a structure shown by the following formula (1) are disclosed. wherein A represents an alkylidene group, an alkylene group, a cyclohexylene group, or a phenylene group, and B represents a linear or branched alkylene group or an alkylidene group having 1 to 6 carbon atoms.

Abstract: The present invention provides an emulsion composition which has been increased in sulfonic group content, yet has sufficient water resistance and has been enhanced in properties such as small resistance, film-forming property, etc. The emulsion composition contains (A) a water-based solvent, (B) an organic solvent, (C) a sulfonic group-containing polymer soluble in the component (A), and (D) a polymer soluble in the component (B) but insoluble in water. This emulsion composition is enhanced in small resistance and yet has sufficient water resistance and film-forming property.

Abstract: A non-specific adsorption inhibitor includes a water-soluble polymer obtained by polymerizing a monomer unit that includes a monomer (A) that forms a polymer that has a lower critical solution temperature (LCST) of 80° C. or less in an aqueous solution under normal pressure when subjected to homopolymerization, and a monomer (B) that forms a polymer that does not have the LCST in an aqueous solution under normal pressure when subjected to homopolymerization.

Abstract: A method for producing magnetic particles includes forming a hydrophobic first polymer layer on the surface of a mother particle containing superparamagnetic particles, forming a second polymer layer having glycidyl groups at least on its surface on the first polymer layer, and introducing a polar group containing one or more of at least one atom selected from the group consisting of an oxygen atom, a nitrogen atom, and a sulfur atom by chemically modifying the glycidyl groups.

Abstract: Magnetic particles comprising a group shown by the following formula (1): wherein R1 and R2 individually represent a hydroxyl group, a group shown by the following formula (2), or a group shown by the following formula (3), provided that R1 and R2 are not both hydrogen atoms, wherein R3 represents an a linear, branched, or cyclic alkylene group having 2 to 6 carbon atoms or an arylene group, and wherein R4 is a hydrogen atom or an alkyl group.

Abstract: A method for stabilizing a protein by adding a copolymer to a composition containing the protein where the copolymer has: a repeating unit (A) represented by the following formula (1) and a repeating unit (B) represented by the following formula (2): wherein R1, R2, R3 and R4 are defined in the description.

Abstract: A coating agent for preventing nonspecific adsorption of a substance, which comprises a water-soluble copolymer (P) comprising a repeating unit (A) represented by the following formula (1): wherein R0 represents a hydrogen atom or a methyl group and X represents a group represented by the following formula (1a): wherein R1 and R2 independently represent a hydrogen atom or unsubstituted or substituted an alkyl group having from 1 to 8 carbon atoms or formula (1b): wherein R3 and R4 independently represent a single bond, substituted or unsubstituted methylene or substituted or unsubstituted divalent alkylene group having from 2 to 7 carbon atoms wherein total of the number of carbon atoms of R3 and R4 is from 4 to 10, and Y represents any one of a single bond, O and S; a repeating unit (B) represented by the following formula (2): wherein R5 represents a hydrogen atom or a methyl group and Z represents an organic group containing at least one aldo group or keto group; and a hydrazide compound (H

Abstract: a nonspecific adsorption inhibitor of a substance relating to a living body, which inhibits nonspecific adsorption of a substance relating to a living body such as various species of proteins which are used in clinical diagnostic agents, clinical diagnosis devices, biochips and the like, and a method for coating an article using said nonspecific adsorption inhibitor.

Abstract: A reagent for latex aggregation reaction contains water-soluble polymer having a repeating unit presented by the following formula (1): wherein R1 and R2 each independently represents a hydrogen atom or a substituted or unsubstituted alkyl group having 1 to 8 carbon atoms.

Abstract: Carrier polymer particles comprising organic polymer particles having a particle diameter of 0.1 to 20 micrometers and a saccharide with which the surface of the organic polymer particles is covered, the organic polymer particles and the saccharide being chemically bonded.

Abstract: A protein stabilizing agent comprising a copolymer comprising: a repeating unit (A) represented by the following formula (1) and a repeating unit (B) represented by the following formula (2): wherein R1, R2, R3 and R4 are defined in the description.