Patents by Inventor Kouki Horikoshi

Kouki Horikoshi has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Process for producing heparinase with a bacilius strain
    Patent number: 5455162
    Abstract: A newly discovered microorganism is described that was isolated in biologically pure culture from soil and designated Bacillus sp. strain BH100 (FERM BP-2613 (FERM P-10408)). This strain is used in a new process for production of extracellular heparinase. Additionally a new heparinase having an optimum temperature for activity in the range of 45.degree. to 50.degree. C. is disclosed.
    Type: Grant
    Filed: August 3, 1994
    Date of Patent: October 3, 1995
    Assignee: Research Development Corporation of Japan
    Inventors: Robert W. Bellamy, Kouki Horikoshi
  • Thermostable strains of the genus thermus capable of producing a .beta. lactosidase
    Patent number: 5432078
    Abstract: Biologically pure strains of Thermus sp. FERM BP-1678, FERM BP-1679 and FERM BP-1680 have been isolated, and are capable of producing a beta-galactosidase. The beta-galactosidase produced by these strains has specific characteristics wherein the enzyme is optimum at a temperature of 75 to 85 degrees celsius and pH of 4.5 to 6.5. Further, the enzymatic activity is reduced by at most 10% in the presence of 50 millimoles (mM) of galactose and glucose, respectively.
    Type: Grant
    Filed: October 28, 1993
    Date of Patent: July 11, 1995
    Assignees: Research Development Corporation of Japan, Kenkyusho, Rikagaku, Morinaga Milk Industry Co., Ltd.
    Inventors: Mitsunori Takase, Kouki Horikoshi
  • Heparinase-producing microorganism belonging to the genus bacillus
    Patent number: 5362645
    Abstract: A newly discovered microorganism is described that was isolated in biologically pure culture from soil and designated Bacillus sp. strain BH100 (FERM BP-2613 (FERM P-10408)). This strain is used in a new process for production of extracellular heparinase. Additionally a new heparinase having an optimum temperature for activity in the range of 45.degree. to 50.degree. C. is disclosed.
    Type: Grant
    Filed: November 27, 1991
    Date of Patent: November 8, 1994
    Assignees: Rsearch Development Corporation of Japan, Rikagaku Kenkyusho
    Inventors: Robert W. Bellamy, Kouki Horikoshi
  • .beta.-galactosidase from Thermus sp
    Patent number: 5283189
    Abstract: A .beta.-galactosidase having a high thermostability is produced by Thermus sp. FERM BP-1678, FERM BP-1679, and FERM BP-1680. The .beta.-galactosidase has an optimum temperature of 75 to 85 degrees celsius, and an optimum pH of 4.5 to 6.5 and an enzymatic activity which is not lowered substantially by 50 mM each of galactose and glucose. The .beta.-galactosidase is used to hydrolyze lactose in foods, such as milk, at a high temperature at which the putrefaction by saprophytes is difficult.
    Type: Grant
    Filed: August 9, 1991
    Date of Patent: February 1, 1994
    Assignees: Research Development Corporation of Japan, Rikagaku Kenkyusho, Morinaga Milk Industry
    Inventors: Mitsunori Takase, Kouki Horikoshi
  • Heparinase produced by microorganism belonging to the genus bacillus
    Patent number: 5145778
    Abstract: A newly discovered microorganism is described that was isolated in biologically pure culture from soil and designated Bacillus sp. strain BH100 (FERM BP-2613 (FERM P-10408)). This strain is used in a new process for production of extracellular heparinase. Additionally a new heparinase having an optimum temperature for activity in the range of 45.degree. to 50.degree. C. is disclosed.
    Type: Grant
    Filed: November 22, 1989
    Date of Patent: September 8, 1992
    Assignee: Reseaarch Development Corporation of Japan
    Inventors: Robert W. Bellamy, Kouki Horikoshi
  • Microorganism capable of growing in 50% or more organic solvent
    Patent number: 4985363
    Abstract: New microorganisms belonging to Pseudomonas putida or Pseudomonas sp., which are isolated from soil and have tolerance to one or more of hydrocarbons, alcohols, ethers, ketones and their derivatives or their mixture. These new microorganisms can be used in the fields of bioreactor, liquid-waste treatment, protein engineering, etc.
    Type: Grant
    Filed: March 3, 1988
    Date of Patent: January 15, 1991
    Assignee: Research Development Corporation
    Inventors: Akira Inoue, Kouki Horikoshi
  • Method for culturing microorganism
    Patent number: 4981800
    Abstract: A method for culturing microorganisms belonging to the genus Pseudomonas or the genus Escherichia and having tolerance to an organic solvent such as any one of hydrocarbons, alcohols, ethers, ketones and their derivatives or their mixture in a medium containing the organic solvent in a concentration of 0.3% or more. The present method can be widely utilized in the fields of bioreactor, liquid-waste treatment, protein engineering, etc.
    Type: Grant
    Filed: March 29, 1988
    Date of Patent: January 1, 1991
    Assignee: Research Development Corporation of Japan
    Inventors: Akira Inoue, Kouki Horikoshi
  • Fragrant synthetic resin product and method of producing the same
    Patent number: 4356115
    Abstract: A dry-pulverized cyclodextrin inclusion compound which includes a perfume material is mixed with a thermoplastic synthetic resin to provide a synthetic resin product having a long lasting fragrance.
    Type: Grant
    Filed: April 27, 1981
    Date of Patent: October 26, 1982
    Inventors: Ichiro Shibanai, Kouki Horikoshi, Nobuyuki Nakamura
  • Solid fuel
    Patent number: 4292044
    Abstract: A solid fuel includes a mixture of a liquid fuel and cyclodextrin or a cyclodextrin - containing decomposition product of starch and a second combustible substance such as pulp.
    Type: Grant
    Filed: April 4, 1980
    Date of Patent: September 29, 1981
    Assignee: Kyoshin Co., Ltd.
    Inventors: Ichiro Shibanai, Kouki Horikoshi, Nobuyuki Nakamura
  • Process for production of oil from oil sand
    Patent number: 4255249
    Abstract: A process for the production of oil from oil sand includes adding cyclodextrin or a starch decomposition product containing cyclodextrin to oil sand to convert petroleum in the oil sand to an inclusion compound and separating and collecting petroleum alone from the inclusion compound.
    Type: Grant
    Filed: June 22, 1979
    Date of Patent: March 10, 1981
    Assignee: Kyoshin Co., Ltd.
    Inventors: Ichiro Shibanai, Kouki Horikoshi, Nobuyuki Nakamura
  • Method for removing odor from fluid
    Patent number: 4225381
    Abstract: A method for removing malodorous sulfur compounds from a fluid containing such compounds. In this method, fungi belonging to genera Cephalosporium, Paecilomyces, Penicillium, Aspergillus, Trichoderma and Mucor can be used for effectively removing malodorous sulfur compounds from a fluid.
    Type: Grant
    Filed: December 12, 1978
    Date of Patent: September 30, 1980
    Assignee: Oji Paper Co., Ltd.
    Inventors: Hisao Ishikawa, Yukio Kita, Kouki Horikoshi