Abstract: To provide an immunomodulator in which DNA can be administered orally or percutaneously, not through injection, or can daily be taken like food, or an immunomodulator food or feed DNA derived from cells of procaryotes such as Bacillus subtilis, lactic acid bacteria, amino acid producing bacteria and Escherichia coli is added to food or molded to be able to administer the same orally, percutaneously or permucosally, or formed into food, feed or the like.

Abstract: An antimicrobial composition for eucaryotic microorganisms and method of suppressing the growth of eucaryotic microorganisms requires a procaryotic DNA extract. The antimicrobial composition is effective against numerous types of eucaryotic microorganisms and can be safely added to food and cosmetic products.

Abstract: A diaphragm for speakers comprises a self-support, shaped body including a tightly woven synthetic polymer fiber cloth substrate which has, at least a diaphragm portion and edge portion shaped integrally with and extending from the diaphragm portion. The diaphragm portion of the cloth substrate had a polymer resin at least partially impregnated therein and the edge portion has a relatively flexible polymer material at least partially impregnated therein so that the edge portion is lower in stiffness than the diaphragm portion. The diaphragm-edge integral molding is fabricated by applying the respective types of polymers to the diaphragm and edge portions of the cloth substrate and subjecting the applied substrate to hot pressing in a mold capable of forming the integral molding. When applied as dynamic speakers, the integral molding exhibits a broad frequency band, low distortion rates and high sound quality.

Abstract: A diaphragm for speakers comprises a self-support, shaped body including a tightly woven synthetic polymer fiber cloth substrate which has at least a diaphragm portion and edge portion shaped integrally with and extending from the diaphragm portion. The diaphragm portion of the cloth substrate had a polymer resin at least partially impregnated therein and the edge portion has a relatively flexible polymer material at least partially impregnated therein so that the edge portion is lower in stiffness than the diaphragm portion. The diaphragm-edge integral molding is fabricated by applying the respective types of polymers to the diaphragm and edge portions of the cloth substrate and subjecting the applied substrate to hot pressing in a mold capable of forming the integral molding. When applied as dynamic speakers, the integral molding exhibits a broad frequency band, low distortion rates and high sound quality.

Abstract: A speaker which is thin but which is capable of providing high-fidelity reproduction and ensuring a suitable level of sound pressure even when it is brought close to a wall. A closed chamber is formed behind one part of a disphragm mounted in an enclosure, and an open chamber is formed behind another part of the diaphragm. At least one voice coil driver unit is connected to the diaphragm. The phase difference between sounds radiated from the front and rear surfaces of the diaphragm is increased as large as possible by using an acoustic duct for the sound radiated through the open chamber, thereby minimizing cancellation of sounds and improving the sound pressure level.

Abstract: A sound reproducing apparatus for use in a vehicle having a speaker system constituted by at least one acoustic duct and a speaker unit disposed at a throat of the acoustic duct, an opening formed at the other end of the acoustic duct facing the passenger compartment of a vehicle. The apparatus is arranged such that, F0 and Fs are substantially equal to each other. Where Fs is the lowest frequency in a frequency range within which the imaginary part of the acoustic impedance at the sound radiating surface of the speaker system in the direction of the space within the passsenger compartment is zero and F0 is the low-range resonance frequency of the speaker system itself in the free space.

Abstract: A diaphragm for loudspeakers comprises chitin as a natural high polymeric material having a large value of Young's modulus and kraft pulp having large mechanical internal loss. Therefore, the deformation and the partial vibrations of the diaphragm during diaphragm operation do not come out due to the use of the chitin, because the flexural rigidity of the diaphragm is considerably large. Mechanical internal loss is also large owing to the use of the kraft pulp. As a result, it is possible to obtain a loudspeaker which has little fluctuation in frequency response, and which provides a superior sound pressure-frequency response, a superior distortion factor and a superior phase response.

Abstract: The present invention relates to a new mutant strain of Escherichia coli and its use for the preparation of glutathione.The present invention is based upon the discovery that a certain mutant strain which we have induced from a wild strain of Escherichia coli is capable of accumulating large amounts of glutathione and an enzyme system for the synthesis of glutathione in the cultured broth.The new mutant strain is preferably Escherichia coli designated Escherichia coli RC 912 p (FERM-BP No. 48).

Abstract: The present invention relates to a new mutant strain induced from a wild strain of the genus Escherichia, which is active upon a .gamma.-glutamyl-L-cystein synthesizing enzyme system and capable of releasing .gamma.-glutamyl-L-cystein synthetase from inhibition by glutathione.It preferably is Escherichia coli RC 912 (FERM-BP No. 47). The present invention also contemplates the preparation of glutathione by (1) culturing the foregoing strain in a culture medium' or (2) culturing said strain to first accumulate a .gamma.-glutamyl-L-cystein synthesizing enzyme system, and placing the latter into contact with a substrate of L-glutamic acid, L-cysteine and glycerine to form gluthatione by enzymatic reaction.

Abstract: A speaker diaphragm comprises a composite film prepared by combining a reinforcing material such as a mica, a needle or fiber filler, or talc, with a polybisphenol phthalate resin consisting of an aromatic dicarboxylic acid and a dihydric phenol.

Abstract: An improved method for the fermentative production of L-threonine in a high yield, which comprises cultivating a methionine metabolism-antagonist resistant mutant of Serratia marcescens having L-threonine productivity in a broth to form and accumulate L-threonine therein and recovering accumulated L-threonine from the broth.

Abstract: An acoustic diaphragm for speakers having a sandwich structure constituted by a core material comprising an elongated web material bent to have a plurality of radial projections, and upper and lower surface members adhered to the upper and lower edges of the core member, as well as a method of producing the same. The acoustic diaphragm of the invention has a reduced weight while exhibiting a large flexural rigidity so that the nodal line during the resonance vibration can have a circular form which in turn offers a circular form of nodal line and increased speaker power. Also, the method of producing the invention permits easy fabrication of the acoustic diaphragm having a sandwich structure.