Patents by Inventor Koushi Iwata

Koushi Iwata has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20240041854
    Abstract: Problem To provide a novel cold medicine or antiviral agent. Means for Solution A cold medicine comprising a compound represented by formula (1) or a pharmaceutically acceptable salt thereof.
    Type: Application
    Filed: June 30, 2021
    Publication date: February 8, 2024
    Inventors: Koushi IWATA, Kaoru IMAI
  • Patent number: 10570117
    Abstract: Phenylimidazole compounds of formula (1) shown below and pharmaceutically acceptable salts thereof: Also disclosed are a pharmaceutical composition and a lipoprotein lipase activator, each containing one of the phenylimidazole compounds.
    Type: Grant
    Filed: October 25, 2016
    Date of Patent: February 25, 2020
    Assignee: Otsuka Pharmaceutical Factory, Inc.
    Inventors: Koushi Iwata, Tadao Shibutani, Satoshi Kido, Daisuke Mori, Hidenori Yoshioka, Hikaru Nakata, Akiko Ishimaru
  • Publication number: 20180354930
    Abstract: Provided is a compound (chemotherapeutic agent) effective in the prevention and treatment of hyperlipidemia, obesity, or the like.
    Type: Application
    Filed: October 25, 2016
    Publication date: December 13, 2018
    Inventors: Koushi Iwata, Tadao Shibutani, Satoshi Kido, Daisuke Mori, Hidenori Yoshioka, Hikaru Nakata, Akiko Ishimaru
  • Publication number: 20160367584
    Abstract: An object of the present invention is to provide a protective agent for the keratoconjunctiva or a suppressive agent for a keratoconjunctival disorder having an excellent suppressive effect on a keratoconjunctival disorder. The invention relates to a protective agent for the keratoconjunctiva or a suppressive agent for a keratoconjunctival disorder containing glucosylglycerol as an active ingredient, use of glucosylglycerol for the manufacture of a pharmaceutical for protecting a keratoconjunctiva or suppressing a keratoconjunctival disorder and a method of protecting a keratoconjunctiva or suppressing a keratoconjunctival disorder comprising administering glucosylglycerol.
    Type: Application
    Filed: September 1, 2016
    Publication date: December 22, 2016
    Inventors: Kyo Aizawa, Yoshihisa Iida, Takashi Shimoida, Yasuhiro Kotani, Koushi Iwata, Kazuhisa Doi
  • Patent number: 8895599
    Abstract: The present invention provides pharmaceutical compositions containing benzene compound(s) represented by General Formula (1) below and, particularly, LPL-activating compositions for use in hyperlipidemia therapeutic and preventive agents, anti-obesity agents, and the like: wherein R1, R2, R3 and R4 are as defined in the specification.
    Type: Grant
    Filed: June 28, 2013
    Date of Patent: November 25, 2014
    Assignee: Otsuka Pharmaceutical Factory, Inc.
    Inventors: Irina Neagu, Michael Ohlmeyer, Vidyadhar M. Paradkar, Kurt W. Saionz, Koushi Iwata, Takashi Okamura, Tadao Shibutani
  • Publication number: 20130296342
    Abstract: The present invention provides pharmaceutical compositions containing benzene compound(s) represented by General Formula (1) below and, particularly, LPL-activating compositions for use in hyperlipidemia therapeutic and preventive agents, anti-obesity agents, and the like: wherein R1, R2, R3 and R4 are as defined in the specification.
    Type: Application
    Filed: June 28, 2013
    Publication date: November 7, 2013
    Applicant: OTSUKA PHARMACEUTICAL FACTORY, INC.
    Inventors: Irina NEAGU, Michael OHLMEYER, Vidyadhar M. PARADKAR, Kurt W. SAIONZ, Koushi IWATA, Takashi OKAMURA, Tadao SHIBUTANI
  • Patent number: 8334248
    Abstract: The present invention provides a disinfectant that contains olanexidine in a concentration sufficient to exhibit an effective bactericidal effect, and that has hardly any side effects such as skin irritation. Specifically, the present invention provides a disinfectant containing an aqueous solution that contains olanexidine and at least an equimolar amount of gluconic acid, and substantially contains neither an acid other than gluconic acid nor a salt of the acid other than gluconic acid.
    Type: Grant
    Filed: September 10, 2010
    Date of Patent: December 18, 2012
    Assignees: Otsuka Pharmaceutical Co., Ltd., Otsuka Pharmaceutical Factory, Inc.
    Inventors: Kazuyoshi Miyata, Yasuhide Inoue, Akifumi Hagi, Motoya Kikuchi, Hitoshi Ohno, Kinji Hashimoto, Kinue Ohguro, Tetsuya Sato, Hidetsugu Tsubouchi, Hiroshi Ishikawa, Takashi Okamura, Koushi Iwata
  • Patent number: 8329739
    Abstract: [Object] To provide a pharmaceutical product (chemotherapeutic agent) effective in the prevention and treatment of hyperlipidemia, obesity, etc. [Solving Means] A phenylimidazole compound represented by the following General Formula (1): wherein, R1 represents a hydrogen atom, a phenyl lower alkyl group optionally having a substituent, or a pyridyl lower alkyl group optionally having a substituent, and the benzene ring and the pyridine ring are optionally substituted with 1 or 2 substituents selected from the group consisting of halogen atoms, cyano group and halogen-substituted lower alkyl groups. One of R2 and R3 represents a hydrogen atom and the other represents a lower alkoxy group. R4 represents a phenyl group optionally having a substituent. R5 and R6 are the same or different, and represent a hydrogen atom or a lower alkyl group. R7 and R8 are the same or different, and represent a hydrogen atom or a lower alkoxy group.
    Type: Grant
    Filed: February 3, 2010
    Date of Patent: December 11, 2012
    Assignee: Otsuka Pharmaceutical Factory, Inc.
    Inventors: Tadao Shibutani, Koushi Iwata, Satoshi Kido
  • Publication number: 20110275823
    Abstract: [Object] To provide a pharmaceutical product (chemotherapeutic agent) effective in the prevention and treatment of hyperlipidemia, obesity, etc. [Solving Means] A phenylimidazole compound represented by the following General Formula (1): wherein, R1 represents a hydrogen atom, a phenyl lower alkyl group optionally having a substituent, or a pyridyl lower alkyl group optionally having a substituent, and the benzene ring and the pyridine ring are optionally substituted with 1 or 2 substituents selected from the group consisting of halogen atoms, cyano group and halogen-substituted lower alkyl groups. One of R2 and R3 represents a hydrogen atom and the other represents a lower alkoxy group. R4 represents a phenyl group optionally having a substituent. R5 and R6 are the same or different, and represent a hydrogen atom or a lower alkyl group. R7 and R8 are the same or different, and represent a hydrogen atom or a lower alkoxy group.
    Type: Application
    Filed: February 3, 2010
    Publication date: November 10, 2011
    Applicant: OTSUKA PHARMACEUTICAL FACTORY, INC.
    Inventors: Tadao Shibutani, Koushi Iwata, Satoshi Kido
  • Publication number: 20110065728
    Abstract: The present invention provides pharmaceutical compositions containing benzene compound(s) represented by General Formula (1) below and, particularly, LPL-activating compositions for use in hyperlipidemia therapeutic and preventive agents, anti-obesity agents, and the like: wherein R1, R2, R3 and R4 are as defined in the specification.
    Type: Application
    Filed: May 14, 2008
    Publication date: March 17, 2011
    Applicant: OTSUKA PHARMACEUTICAL FACTORY, INC.
    Inventors: Irina Neagu, Michael Ohlmeyer, Vidyadhar M. Paradkar, Kurt W. Saionz, Koushi Iwata, Takashi Okamura, Tadao Shibutani
  • Publication number: 20100331423
    Abstract: The present invention provides a disinfectant that contains olanexidine in a concentration sufficient to exhibit an effective bactericidal effect, and that has hardly any side effects such as skin irritation. Specifically, the present invention provides a disinfectant containing an aqueous solution that contains olanexidine and at least an equimolar amount of gluconic acid, and substantially contains neither an acid other than gluconic acid nor a salt of the acid other than gluconic acid.
    Type: Application
    Filed: September 10, 2010
    Publication date: December 30, 2010
    Applicants: Otsuka Pharmaceutical Co., Ltd., Otsuka Pharmaceutical Factory, Inc.
    Inventors: Kazuyoshi Miyata, Yasuhide Inoue, Akifumi Hagi, Motoya Kikuchi, Hitoshi Ohno, Kinji Hashimoto, Kinue Ohguro, Tetsuya Sato, Hidetsugu Tsubouchi, Hiroshi Ishikawa, Takashi Okamura, Koushi Iwata
  • Patent number: 7829518
    Abstract: The present invention provides a disinfectant that contains olanexidine in a concentration sufficient to exhibit an effective bactericidal effect, and that has hardly any side effects such as skin irritation. Specifically, the present invention provides a disinfectant containing an aqueous solution that contains olanexidine and at least an equimolar amount of gluconic acid, and substantially contains neither an acid other than gluconic acid nor a salt of the acid other than gluconic acid.
    Type: Grant
    Filed: May 25, 2004
    Date of Patent: November 9, 2010
    Assignees: Otsuka Pharmaceutical Co., Ltd., Otsuka Pharmaceutical Factory, Inc,
    Inventors: Kazuyoshi Miyata, Yasuhide Inoue, Akifumi Hagi, Motoya Kikuchi, Hitoshi Ohno, Kinji Hashimoto, Kinue Ohguro, Tetsuya Sato, Hidetsugu Tsubouchi, Hiroshi Ishikawa, Takashi Okamura, Koushi Iwata
  • Patent number: 7825080
    Abstract: The present invention provides a disinfectant that contains olanexidine in a concentration sufficient to exhibit an effective bactericidal effect, and that has hardly any side effects such as skin irritation. Specifically, the present invention provides a disinfectant containing an aqueous solution that contains olanexidine and at least an equimolar amount of gluconic acid, and substantially contains neither an acid other than gluconic acid nor a salt of the acid other than gluconic acid.
    Type: Grant
    Filed: October 27, 2006
    Date of Patent: November 2, 2010
    Assignees: Otsuka Pharmaceutical Co., Ltd., Otsuka Pharmaceutical Factory, Inc.
    Inventors: Kazuyoshi Miyata, Yasuhide Inoue, Akifumi Hagi, Motoya Kikuchi, Hitoshi Ohno, Kinji Hashimoto, Kinue Ohguro, Tetsuya Sato, Hidetsugu Tsubouchi, Hiroshi Ishikawa, Takashi Okamura, Koushi Iwata
  • Publication number: 20070041866
    Abstract: The present invention provides a disinfectant that contains olanexidine in a concentration sufficient to exhibit an effective bactericidal effect, and that has hardly any side effects such as skin irritation. Specifically, the present invention provides a disinfectant containing an aqueous solution that contains olanexidine and at least an equimolar amount of gluconic acid, and substantially contains neither an acid other than gluconic acid nor a salt of the acid other than gluconic acid.
    Type: Application
    Filed: October 27, 2006
    Publication date: February 22, 2007
    Inventors: Kazuyoshi Miyata, Yasuhide Inoue, Akifumi Hagi, Motoya Kikuchi, Hitoshi Ohno, Kinji Hashimoto, Kinue Ohguro, Tetsuya Sato, Hidetsugu Tsubouchi, Hiroshi Ishikawa, Takashi Okamura, Koushi Iwata
  • Publication number: 20060189500
    Abstract: The present invention provides a disinfectant that contains olanexidine in a concentration sufficient to exhibit an effective bactericidal effect, and that has hardly any side effects such as skin irritation. Specifically, the present invention provides a disinfectant containing an aqueous solution that contains olanexidine and at least an equimolar amount of gluconic acid, and substantially contains neither an acid other than gluconic acid nor a salt of the acid other than gluconic acid.
    Type: Application
    Filed: May 25, 2004
    Publication date: August 24, 2006
    Inventors: Kazuyoshi Miyata, Yasuhide Inoue, Akifumi Hagi, Motoya Kikuchi, Hitoshi Ohno, Kinji Hashimoto, Kinue Ohguro, Tetsuya Sato, Hidetsugu Tsubouchi, Hiroshi Ishikawa, Takashi Okamura, Koushi Iwata