Abstract: The present disclosure provides a composition for improving vascular endothelial function or improving blood flow in peripheral blood vessels, comprising, as an active ingredient, an ingredient derived from a turmeric.

Abstract: The present invention provides a composition having an action to enhance adrenomedullin gene expression. One or more embodiments of the present invention relate to a composition for enhancing adrenomedullin gene expression containing a TRPV1 agonist and a TRPA1 agonist as active ingredients. The TRPV1 agonist can be, for example, at least one selected from capsaicin, 6-shogaol, 6-gingerol and piperine. The TRPA1 agonist can be, for example, at least one selected from allyl isothiocyanate, cinnamaldehyde, diallyl disulfide, ASP7663 and oxylipin.

Abstract: The present invention provides a composition for improving or maintaining quality of life (QOL), comprising, as an active ingredient, a component derived from turmeric. The present invention relates to a composition for improving or maintaining QOL, comprising, as an active ingredient, at least one of turmeronol A, turmeronol B, and bisacurone. The composition of the present invention for improving or maintaining QOL may comprise 20 ?g or more of turmeronol A and turmeronol B in total per daily intake, may comprise 17 ?g or more of turmeronol A per daily intake, may comprise 5 ?g or more of turmeronol B per daily intake, and may comprise 80 ?g or more of bisacurone per daily intake.

Abstract: One or more embodiments of the present invention provide a composition for inhibiting TNF-? or IL-6 production, comprising a component derived from turmeric. One or more embodiments of the present invention relate to a composition for inhibiting TNF-? or IL-6 production, comprising at least one of turmeronol A, turmeronol B, and bisacurone. The composition for inhibiting TNF-? or IL-6 production according to one or more embodiments of the present invention may comprise 20 ?g or more of turmeronol A and turmeronol B in total per daily intake, may comprise 17 ?g or more of turmeronol A per daily intake, may comprise 5 ?g or more of turmeronol B per daily intake, and may comprise 80 ?g or more of bisacurone per daily intake.

Abstract: One or more embodiments of the present invention relate to a composition for improving lipid metabolism or carbohydrate metabolism, comprising a component derived from turmeric. One or more embodiments of the present invention relate to a composition for lowering blood glucose level, reducing blood hemoglobin A1c content, or increasing blood HDL-cholesterol content, a composition for treating or preventing metabolic syndrome, or a composition for improving lipid metabolism or carbohydrate metabolism, wherein each composition comprises, as an active ingredient, at least one of turmeronol A, turmeronol B, and bisacurone. Each composition may comprise 20 ?g or more of turmeronol A and turmeronol B in total per daily intake, may comprise 17 ?g or more of turmeronol A per daily intake, may comprise 5 ?g or more of turmeronol B per daily intake, and may comprise 80 ?g or more of bisacurone per daily intake.

Abstract: The present invention provides a composition for improving vascular endothelial function or improving blood flow in peripheral blood vessels, comprising, as an active ingredient, an ingredient derived from a turmeric. The present invention relates to a composition for improving vascular endothelial function or improving blood flow in peripheral blood vessels, comprising, as an active ingredient, at least one of turmeronol A, turmeronol B and bisacurone. The present invention also relates to a composition for improving vascular endothelial function or improving blood flow in peripheral blood vessels, comprising a turmeric as an active ingredient.

Abstract: This invention provides a composition comprising, as an active ingredient, a turmeric-derived ingredient, which is useful for treatment, prevention, or amelioration of Alzheimer's disease. This invention relates to a composition for treatment of Alzheimer's disease, a composition for suppression of brain nerve cell death, a composition for suppression of microglia activation induced by amyloid ? peptide, or a composition for suppression of PGE2, TNF-?, or IL-1? production induced by amyloid ? peptide comprising, as an active ingredient, a turmeric extract extracted with at least one extraction solvent selected from water and a hydrophilic organic solvent or at least one of termeronol A and termeronol B.

Abstract: The present invention provides a composition for improving vascular endothelial function or improving blood flow in peripheral blood vessels, comprising, as an active ingredient, an ingredient derived from a turmeric. The present invention relates to a composition for improving vascular endothelial function or improving blood flow in peripheral blood vessels, comprising, as an active ingredient, at least one of turmeronol A, turmeronol B and bisacurone. The present invention also relates to a composition for improving vascular endothelial function or improving blood flow in peripheral blood vessels, comprising a turmeric as an active ingredient.

Abstract: A composition comprising (a) and (b), and a food or drink or a medicine comprising the composition, wherein (a) is at least a kind of polyphenols selected from the group consisting of a polyphenol containing 15 mass % or more of proanthocyanidin having a polymerization degree of 1 to 3, hesperidin, a hesperidin derivative, and hesperetin; and (b) is at least a kind of xanthine derivatives, the mass ratio of (a):(b) in the composition being 1:(0.001 to 5), are useful for the prevention, amelioration, or treatment of metabolic syndrome, disorders of lipid metabolism (for example, fatty liver, hyperlipidemia), obesity (for example, visceral fat accumulation, subcutaneous fat accumulation), or the like.

Abstract: A composition comprising (a) and (b), and a food or drink or a medicine comprising the composition, wherein (a) is at least a kind of polyphenols selected from the group consisting of a polyphenol containing 15 mass % or more of proanthocyanidin having a polymerization degree of 1 to 3, hesperidin, a hesperidin derivative, and hesperetin; and (b) is at least a kind of xanthine derivatives, the mass ratio of (a):(b) in the composition being 1:(0.001 to 5), are useful for the prevention, amelioration, or treatment of metabolic syndrome, disorders of lipid metabolism (for example, fatty liver, hyperlipidemia), obesity (for example, visceral fat accumulation, subcutaneous fat accumulation), or the like.

Abstract: A primary object of the invention is to provide a composition for the prevention, amelioration, or treatment of metabolic syndrome and to provide a food or drink, a medicine, or a feed comprising the composition. A composition for the prevention, amelioration, or treatment of metabolic syndrome, the composition comprising the following (a) and (b): (a) a rose hip extract, and (b) at least a kind of xanthine derivatives.

Abstract: A composition comprising (a) and (b), and a food or drink or a medicine comprising the composition, wherein (a) is at least a kind of polyphenols selected from the group consisting of a polyphenol containing 15 mass % or more of proanthocyanidin having a polymerization degree of 1 to 3, hesperidin, a hesperidin derivative, and hesperetin; and (b) is at least a kind of xanthine derivatives, the mass ratio of (a):(b) in the composition being 1:(0.001 to 5), are useful for the prevention, amelioration, or treatment of metabolic syndrome, disorders of lipid metabolism (for example, fatty liver, hyperlipidemia), obesity (for example, visceral fat accumulation, subcutaneous fat accumulation), or the like.

Abstract: A primary object of the invention is to provide a composition for the prevention, amelioration, or treatment of metabolic syndrome and to provide a food or drink, a medicine, or a feed comprising the composition. A composition for the prevention, amelioration, or treatment of metabolic syndrome, the composition comprising the following (a) and (b): (a) a rose hip extract, and (b) at least a kind of xanthine derivatives.

Abstract: A composition comprising (a) and (b), and a food or drink or a medicine comprising the composition, wherein (a) is at least a kind of polyphenols selected from the group consisting of a polyphenol containing 15 mass % or more of proanthocyanidin having a polymerization degree of 1 to 3, hesperidin, a hesperidin derivative, and hesperetin; and (b) is at least a kind of xanthine derivatives, the mass ratio of (a):(b) in the composition being 1:(0.001 to 5), are useful for the prevention, amelioration, or treatment of metabolic syndrome, disorders of lipid metabolism (for example, fatty liver, hyperlipidemia), obesity (for example, visceral fat accumulation, subcutaneous fat accumulation), or the like.

Abstract: The present invention provides a moisturizer comprising, as an active ingredient, a saccharide having 3-O-?-D-glucopyranosyl-D-glucose as a structural unit. The moisturizer of the present invention improves the water retention capacity of the stratum corneum, and is useful for prevention and improvement of rough skin.

Abstract: The present invention provides a moisturizer comprising heat-killed cells of Lactobacillus plantarum as an active ingredient. The moisturizer of the present invention improves the water retention capacity of the stratum corneum, and is useful for prevention and improvement of rough skin.

Abstract: The present invention relates to an antistress agent comprising as an active ingredient a saccharide containing 3-O-?-D-glucopyranosyl-D-glucose as a structural unit. It is an object of the present invention to provide said antistress agent which is free from side effects as a medicine, and can be taken habitually and also can be ingested simply as a food or a beverage, or the like.

Abstract: The present invention provides a moisturizer comprising heat-killed cells of Lactobacillus plantarum as an active ingredient. The moisturizer of the present invention improves the water retention capacity of the stratum corneum, and is useful for prevention and improvement of rough skin.

Abstract: The present invention provides a moisturizer comprising, as an active ingredient, a saccharide having 3-O-?-D-glucopyranosyl-D-glucose as a structural unit. The moisturizer of the present invention improves the water retention capacity of the stratum corneum, and is useful for prevention and improvement of rough skin.

Abstract: The present invention relates to an antistress agent comprising as an active ingredient a saccharide containing 3-O-?-D-glucopyranosyl-D-glucose as a structural unit. It is an object of the present invention to provide said antistress agent which is free from side effects as a medicine, and can be taken habitually and also can be ingested simply as a food or a beverage, or the like.