Patents by Inventor Kozo Kaibuchi

Kozo Kaibuchi has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Modified protein derived from protein kinase N
    Patent number: 6660837
    Abstract: A object of the present invention is to provide a peptide inhibiting tumorigenesis or metastasis. The present invention is a peptide or derivatives thereof comprising a modified amino acid sequence of Protein Kinase N having the activated Rho protein binding activity and not having protein kinase activity, and a peptide or derivatives thereof comprising a modified amino acid sequence of Protein Kinase N inhibiting the protein kinase activity of Protein Kinase N or the enhancement of the activity and not having protein kinase activity.
    Type: Grant
    Filed: July 24, 1996
    Date of Patent: December 9, 2003
    Assignee: Kirin Beer Kabushiki Kaisha
    Inventors: Kozo Kaibuchi, Yoshitaka Ono, Akihiro Iwamatsu
  • Rho target protein Rho-kinase
    Patent number: 5906819
    Abstract: The object of the present invention is to provide a target protein for the activated Rho protein. The present invention is a protein having activated Rho protein binding activity and protein kinase activity or derivatives thereof. The molecular weight of the protein derived from bovine is about 164 kDa as measured by SDS-PAGE. The protein kinase activity of this protein is enhanced when it binds to the activated Rho protein.
    Type: Grant
    Filed: July 24, 1996
    Date of Patent: May 25, 1999
    Assignee: Kirin Beer Kabushiki Kaisha
    Inventors: Kozo Kaibuchi, Akihiro Iwamatsu, Takeshi Nakano, Masaaki Ito, Nobuaki Takahashi