Patents by Inventor Kozo Kurihara

Kozo Kurihara has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 5153003
    Abstract: A composition comprising a polymer having dispersed therethrough a prostacyclin derivative selected from the group consisting of compounds of formula (I): ##STR1## (in which R.sup.1 represents hydrogen or lower alkyl, R.sup.2 represents a C.sub.3 -C.sub.12 alkyl group or a C.sub.3 -C.sub.12 alkenyl group; and n is an integer from 1 to 5; and pharmaceutically acceptable salts thereof) can be used to make a medical appliance from which the prostaglandin, having antithrombotic properties, will be released gradually and in a controlled way.
    Type: Grant
    Filed: October 18, 1989
    Date of Patent: October 6, 1992
    Assignee: Sankyo Company Limited
    Inventors: Kozo Kurihara, Hironobu Saito, Yukie Misho, Takeshi Oshima
  • Patent number: 5051402
    Abstract: Cyclosporins are useful immunosuppressive, anti-fungal and antiphlogistic agents which are relatively insoluble in water and aqueous fluids (including body fluids). They may be rendered more soluble by the concomitant administration of .alpha.-cyclodextrin, either separately, but essentially simultaneously or, preferably, in admixture.
    Type: Grant
    Filed: September 21, 1990
    Date of Patent: September 24, 1991
    Assignee: Sankyo Company, Limited
    Inventors: Kozo Kurihara, Masaru Murano
  • Patent number: 4990337
    Abstract: Cyclosporins are useful immunosuppressive, anti-fungal and antiphlogistic agents which are relatively insoluble in water and aqueous fluids (including body fluids). They may be rendered more soluble or dispersible in aqueous media by first dissolving them in at least one mono- or di- glyceride of a C.sub.6 -C.sub.10 fatty acid, and the resulting solution can then easily be emulsified in water or an aqueous fluid.
    Type: Grant
    Filed: April 12, 1990
    Date of Patent: February 5, 1991
    Assignee: Sankyo Company Limited
    Inventors: Kozo Kurihara, Masaru Murano
  • Patent number: 4661162
    Abstract: An enteric-soluble composition for coating drugs and the like comprises a conventional enteric-soluble polymer in admixture with a polyanionic polymer which is soluble at low pH values. By altering proportions and types of both polymer, it is possible to alter the pH value at which the composition will disintegrate to release the drug or the like.
    Type: Grant
    Filed: April 13, 1984
    Date of Patent: April 28, 1987
    Assignee: Sankyo Company, Limited
    Inventors: Kozo Kurihara, Yuji Otsuka, Toshio Fukazawa
  • Patent number: 4533562
    Abstract: Solid materials, especially pharmaceutical preparations, are coated, without the use of solvents, with a powdered film-forming polymer and with a liquid plasticizer having an affinity for the polymer.
    Type: Grant
    Filed: April 19, 1984
    Date of Patent: August 6, 1985
    Assignee: Sankyo Company, Limited
    Inventors: Yoshihiko Ikegami, Kozo Kurihara, Izuo Ichikawa, Hisanori Nakane
  • Patent number: 4497847
    Abstract: A plasticizer for film-forming enteric polymers to be used in coating solid pharmaceutical preparations comprises a monoester or diester or both of glycerol with a saturated aliphatic carboxylic acid having from 6 to 10 carbon atoms. This is particularly useful for coating preparations from aqueous suspensions.
    Type: Grant
    Filed: October 11, 1983
    Date of Patent: February 5, 1985
    Assignee: Sankyo Company, Limited
    Inventors: Kozo Kurihara, Izuo Ichikawa, Hisanori Nakane, Yoshihiko Ikegami
  • Patent number: 4341563
    Abstract: Protective coating composition which comprises dispersed fine particles of one or more of compounds selected from a metal salt of a higher fatty acid, a higher fatty acid having a melting point of 40.degree.-90.degree. C., and a wax having a melting point of 40.degree.-90.degree. C. in an aqueous solution of a water-soluble film base and a surface-active agent having an HLB value of about 1.7 to 8.6 or silicon oil.
    Type: Grant
    Filed: May 8, 1980
    Date of Patent: July 27, 1982
    Assignee: Sankyo Company Limited
    Inventors: Kozo Kurihara, Toshio Fukazawa, Izuo Ichikawa, Yoshihiko Ikegami, Naohiko Fukiyama, Masaru Ikeda