Abstract: A method is provided for purifying physiologically active proteins, especially antibodies, in order to remove impurities such as DNA contaminants and viruses with minimal loss of physiologically active proteins. The physiologically active protein is introduced into an aqueous solution of low conductivity at a pH of below the isoelectric point of the physiologically active protein to precipitate impurities as particles. The particles are removed, leaving a purified physiologically active protein.

Abstract: A method is provided for purifying physiologically active proteins, especially antibodies, in order to remove impurities such as DNA contaminants and viruses with minimal loss of physiologically active proteins. The physiologically active protein is introduced into an aqueous solution of low conductivity at a pH of below the isoelectric point of the physiologically active protein to precipitate impurities as particles. The particles are removed, leaving a purified physiologically active protein.

Abstract: An overhead line damper capable of suppressing a lift force that an overhead line receives due to wind is provided. A damper 1 for an overhead line that is provided at an overhead line L2 includes a clamping mechanism (a pair of hinge pieces 21a and 21b) that is fitted to an outer circumferential surface of the overhead line L2, and a rotary member 4 with a lower part attached to weights 3a and 3b, and an upper part rotatably attached to the clamping mechanism, and the clamping mechanism has a regulation part (an opening part 24) that regulates a rotation range of the rotary member 4 so that the weights 3a and 3b rotate within an angle range from ±20 degrees to ±40 degrees inclusive in a vertical direction.

Abstract: A method for manufacturing an antibody formulation in which DNA contaminants are removed by binding the antibody to a protein-A or probtin-G affinity column and eluting the antibody with an acidic eluting solution, preferably of low conductivity.

Abstract: An overhead line damper capable of suppressing a lift force that an overhead line receives due to wind is provided. A damper 1 for an overhead line that is provided at an overhead line L2 includes a clamping mechanism (a pair of hinge pieces 21a and 21b) that is fitted to an outer circumferential surface of the overhead line L2, and a rotary member 4 with a lower part attached to weights 3a and 3b, and an upper part rotatably attached to the clamping mechanism, and the clamping mechanism has a regulation part (an opening part 24) that regulates a rotation range of the rotary member 4 so that the weights 3a and 3b rotate within an angle range from ±20 degrees to ±40 degrees inclusive in a vertical direction.

Abstract: A method for manufacturing an antibody formulation in which DNA contaminants are removed by binding the antibody to a protein-A or probtin-G affinity column and eluting the antibody with an acidic eluting solution, preferably of low conductivity.

Abstract: A method for manufacturing an antibody formulation in which DNA contaminants are removed by binding the antibody to a protein-A or probtin-G affinity column and eluting the antibody with an acidic eluting solution, preferably of low conductivity.

Abstract: A method is provided for purifying physiologically active proteins, especially antibodies, in order to remove impurities such as DNA contaminants and viruses with minimal loss of physiologically active proteins. The physiologically active protein is introduced into an aqueous solution of low conductivity at a pH of below the isoelectric point of the physiologically active protein to precipitate impurities as particles. The particles are removed, leaving a purified physiologically active protein.

Abstract: A method for removing contaminant DNA in a sample containing a physiologically active protein, which comprises the following steps: 1) converting the sample containing a physiologically active protein into a neutral aqueous solution of low conductivity; and 2) removing the resulting particles.

Abstract: A method for removing contaminant DNA in a sample containing a physiologically active protein, which comprises the following steps: 1) converting the sample containing a physiologically active protein into a neutral aqueous solution of low conductivity; and 2) removing the resulting particles.

Abstract: A method for removing contaminant DNA in a sample containing a physiologically active protein, which comprises the following steps: 1) converting the sample containing a physiologically active protein into a neutral aqueous solution of low conductivity; and 2) removing the resulting particles.

Abstract: Problems to be Solved: The present invention provides a simpler and less expensive method for purifying physiologically active proteins, especially antibodies, which can ensure removal of impurities such as DNA contaminants and viruses, and which can minimize a loss of physiologically active proteins. Means for Solving the Problems: A method for removing impurities in a physiologically active protein-containing sample, which comprises the following steps: 1) allowing the physiologically active protein-containing sample to be converted into an aqueous solution of low conductivity at a pH below the isoelectric point of the physiologically active protein; and 2) removing the resulting particles.

Abstract: A method for removing contaminant DNA in a sample containing a physiologically active protein, which comprises the following steps: