Patents by Inventor Kozo Tanabe

Kozo Tanabe has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Compound, arugomycin
    Patent number: 4598146
    Abstract: An anthracycline compound, Arugomycin, having the physicochemical properties set forth below is produced by aerobically cultivating an Arugomycin-producing Streptomyces strain in a suitable culture medium, and recovering from the culture the anthracycline compound, Arugomycin.(1) Color and form:Orange powder(2) Melting point:207.degree. to 213.degree. C. (decomposed)(3) Specific rotatory power:[.alpha.].sub.D.sup.25 =+112.degree.(C: 0.1, chloroform:methanol=9:1)(4) Elementary analysis (%):______________________________________ C H O N ______________________________________ Found 56.2 6.9 35.1 1.8 Calcd. 56.7 6.7 34.9 1.7 ______________________________________(5) Ultraviolet and visible absorption spectrum: as shown in FIG. 1. ______________________________________ .lambda..sub.max (E.sup.1% .sub.1cm) ______________________________________ CH.sub.3 OH 235(363), 258(167), 292(61), 476(104) 0.1N HCl + CH.sub.3 OH 235(387), 258(159), 292(61), 468(110) 0.1N NaOH + CH.sub.
    Type: Grant
    Filed: February 24, 1984
    Date of Patent: July 1, 1986
    Assignee: Kirin Beer Kabushiki Kaisha
    Inventors: Noboru Otake, Hiroyuki Kawai, Yoichi Hayakawa, Masaya Nakagawa, Kanji Imamura, Kozo Tanabe
  • Antibiotic, Spicamycin
    Patent number: 4565781
    Abstract: An antibiotic, Spicamycin, having the physicochemical properties set forth below is produced by aerobically cultivating a Spicamycin-producing Streptomyces strain in a suitable culture medium, and recovering from the culture the antibiotic, Spicamycin.(1) Color and properties: Weakly acidic white powder(2) Melting point: 215.degree. to 220.degree. C. (decomposed)(3) Specific rotatory power: [.alpha.].sub.D.sup.25 =+15.degree. (C: 0.15, in methanol)(4) Elementary analysis (Found): C: 57.4%, H: 8.3%; N: 15.7%, O: 18.6%(5) Ultraviolet absorption spectrum (maximum):______________________________________ CH.sub.3 OH 264 nm (E.sub.1cm.sup.1% 257) 0.01N NaOH + CH.sub.3 OH 272 nm (E.sub.1cm.sup.1% 226) 0.01N HCl + CH.sub.3 OH 273 nm (E.sub.1cm.sup.1% 258) ______________________________________(6) Infrared absorption spectrum (as measured by the potassium bromide method): As shown in FIG. 2.(7) Solubility in Solvent: Soluble in basic water, dimethyl sulfoxide, methanol, ethanol, n-propanol, and n-butanol.
    Type: Grant
    Filed: February 24, 1984
    Date of Patent: January 21, 1986
    Assignee: Kirin Beer Kabushiki Kaisha
    Inventors: Noboru Otake, Yoichi Hayakawa, Hiroyuki Kawai, Masaya Nakagawa, Kozo Tanabe, Junichiro Mochizuki
  • Physiologically active polysaccharides, production and uses thereof
    Patent number: 4313934
    Abstract: A physiologically active polysaccharide is prepared by treating autolysis-insoluble matters of yeasts of Saccharomyces with a yeast cell wall-lytic enzyme and obtaining a water-soluble physiologically active substance in the resulting solution-fraction. The novel polysaccharide possesses specific physical and chemical properties, and provides a chemotherapeutic agent such as a carcinostatic agent which can be used in the treatment of implanted tumors in mice and rats and an interferon inducer.
    Type: Grant
    Filed: April 17, 1980
    Date of Patent: February 2, 1982
    Assignee: Kirin Beer Kabushiki Kaisha
    Inventors: Kumpei Kitamura, Shigeru Matsuki, Kozo Tanabe