Patents by Inventor Kozo UCHIYAMA

Kozo UCHIYAMA has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Knockout mouse, method for screening substance for suppressing mesial temporal lobe epilepsy, and method for selecting technique for suppressing mesial temporal lobe epilepsy
    Patent number: 10398134
    Abstract: Provided are a knockout mouse, a method for screening a substance for suppressing mesial temporal lobe epilepsy, and a method for selecting a technique for suppressing mesial temporal lobe epilepsy. A knockout mouse 30 or more days of age that has lost the function of the Girdin gene in at least the nervous tissues and exhibits the phenotypes of (1), (2), and (3) below. (1) hippocampal sclerosis should be present, (2) extrahippocampal brain damage should be limited, and (3) spontaneous epilepsy that can be said to be of hippocampal origin should be present.
    Type: Grant
    Filed: October 13, 2015
    Date of Patent: September 3, 2019
    Assignee: NATIONAL UNIVERSITY CORPORATION NAGOYA UNIVERSITY
    Inventors: Masato Asai, Masahide Takahashi, Naoya Asai, Atsushi Enomoto, Kozo Uchiyama
  • KNOCKOUT MOUSE, METHOD FOR SCREENING SUBSTANCE FOR SUPPRESSING MESIAL TEMPORAL LOBE EPILEPSY, AND METHOD FOR SELECTING TECHNIQUE FOR SUPPRESSING MESIAL TEMPORAL LOBE EPILEPSY
    Publication number: 20170223937
    Abstract: Provided are a knockout mouse, a method for screening a substance for suppressing mesial temporal lobe epilepsy, and a method for selecting a technique for suppressing mesial temporal lobe epilepsy. A knockout mouse 30 or more days of age that has lost the function of the Girdin gene in at least the nervous tissues and exhibits the phenotypes of (1), (2), and (3) below. (1) hippocampal sclerosis should be present, (2) extrahippocampal brain damage should be limited, and (3) spontaneous epilepsy that can be said to be of hippocampal origin should be present.
    Type: Application
    Filed: October 13, 2015
    Publication date: August 10, 2017
    Inventors: Masato ASAI, Masahide TAKAHASHI, Naoya ASAI, Atsushi ENOMOTO, Kozo UCHIYAMA