Patents by Inventor Kraig M. Yager

Kraig M. Yager has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • COMPOUNDS AND THERAPEUTIC USES THEREOF
    Publication number: 20150353538
    Abstract: The invention relates to compounds, pharmaceutical compositions and methods useful for treating cancer, systemic or chronic inflammation, rheumatoid arthritis, diabetes, obesity, T-cell mediated autoimmune disease, ischemia, and other complications associated with these diseases and disorders.
    Type: Application
    Filed: January 5, 2015
    Publication date: December 10, 2015
    Applicant: ALZHEIMER'S INSTITUTE OF AMERICA, INC.
    Inventors: J. Adam Willardsen, Jeffrey W. Lockman, Brett R. Murphy, Weston R. Judd, In Chul Kim, Se-Ho Kim, Daniel Feodore Zigar, Kraig M. Yager, Tracey C. Fleischer, Ryan T. Terry-Lorenzo, J. Jay Boniface, Daniel P. Parker, Ian A. McAlexander, Matthew Gregory Bursavich, David D. Dastrup
  • AMINO-PYRIMIDINE COMPOUNDS AS INHIBITORS OF TBK1 AND/OR IKK EPSILON
    Publication number: 20150352108
    Abstract: The invention relates to certain amino-pyrimidine compounds which inhibit TBK1 and/or IKK epsilon and which may therefore find application in treating inflammation, cancer, septic shock and/or Primary open Angle Glaucoma (POAG).
    Type: Application
    Filed: December 23, 2014
    Publication date: December 10, 2015
    Applicant: Alzheimer's Institute of America
    Inventors: Ryan C. Holcomb, Kazuyuki Suzuki, Robert J. Halter, Paul R. Sebahar, Donald A. McLeod, Mark D. Shenderovich, Kraig M. Yager, Matthew Gregory Bursavich, Ashantai J. Yungai, Burt Richards, Paul L. Bartel, Daniel A. Wettstein
  • COMPOUNDS AND THERAPEUTIC USES THEREOF
    Publication number: 20150344426
    Abstract: The invention relates to compounds, pharmaceutical compositions and methods useful for treating cancer, systemic or chronic inflammation, rheumatoid arthritis, diabetes, obesity, T-cell mediated autoimmune disease, ischemia, and other complications associated with these diseases and disorders.
    Type: Application
    Filed: December 24, 2014
    Publication date: December 3, 2015
    Applicant: ALZHEIMER'S INSTITUTE OF AMERICA, INC.
    Inventors: J. Adam Willardsen, Jeffrey W. Lockman, Brett R. Murphy, Weston R. Judd, Kraig M. Yager
  • COMPOUNDS AND THERAPEUTIC USES THEREOF
    Publication number: 20140349989
    Abstract: The invention relates to compounds, pharmaceutical compositions and methods useful for treating cancer, systemic or chronic inflammation, rheumatoid arthritis, diabetes, obesity, T-cell mediated autoimmune disease, ischemia, and complications associated with these diseases and disorders.
    Type: Application
    Filed: December 20, 2013
    Publication date: November 27, 2014
    Applicant: ALZHEIMER'S INSTITUTE OF AMERICA
    Inventors: Dange Vijay Kumar, Paul M. Slattum, Kraig M. Yager, Mark D. Shenderovich, Rajendra Tangallapally, Se-Ho Kim
  • COMPOUNDS AND THERAPEUTIC USES THEREOF
    Publication number: 20130317027
    Abstract: The invention relates to compounds, pharmaceutical compositions and methods useful for treating cancer, systemic or chronic inflammation, rheumatoid arthritis, diabetes, obesity, T-cell mediated autoimmune disease, ischemia, and other complications associated with these diseases and disorders.
    Type: Application
    Filed: December 7, 2012
    Publication date: November 28, 2013
    Applicant: Myrexis, Inc.
    Inventors: J. Adam Willardsen, Jeffrey W. Lockman, Brett R. Murphy, Weston R. Judd, In Chul Kim, Se-Ho Kim, Daniel Feodore Zigar, Kraig M. Yager, Tracey C. Fleischer, Ryan T. Terry-Lorenzo, J. Jay Boniface, Daniel P. Parker, Ian A. McAlexander, Matthew Gregory Bursavich, David M. Dastrup, Christophe Hoarau, David A. Gerrish, Paul R. Sebahar, Dange Vijay Kumar
  • COMPOUNDS AND THERAPEUTIC USES THEREOF
    Publication number: 20120329786
    Abstract: The invention relates to compounds, pharmaceutical compositions and methods useful for treating cancer, systemic or chronic inflammation, rheumatoid arthritis, diabetes, obesity, T-cell mediated autoimmune disease, ischemia, and other complications associated with these diseases and disorders.
    Type: Application
    Filed: August 31, 2012
    Publication date: December 27, 2012
    Applicant: Myrexis, Inc.
    Inventors: J. Adam Willardsen, Jeffrey W. Lockman, Brett R. Murphy, Weston R. Judd, In Chul Kim, Se-Ho Kim, Daniel Feodore Zigar, Kraig M. Yager, Tracey C. Fleischer, Ryan T. Terry-Lorenzo, J. Jay Boniface, Daniel P. Parker, Ian A. McAlexander, Matthew Gregory Bursavich, David M. Dastrup
  • AMINO-PYRIMIDINE COMPOUNDS AS INHIBITORS OF IKK EPSILON AND/OR TBK1
    Publication number: 20120238540
    Abstract: The invention relates to certain amino-pyrimidine compounds that inhibit IKK epsilon and/or TBK1, methods of making such compounds, pharmaceutical compositions comprising such compounds, and the use of these compounds in treating a variety of diseases and disorders.
    Type: Application
    Filed: April 12, 2012
    Publication date: September 20, 2012
    Applicant: Myrexis, Inc.
    Inventors: Ryan C. HOLCOMB, Kazuyuki Suzuki, Robert J. Halter, Paul R. Sebahar, Donald A. McLeod, Mark D. Shenderovich, Kraig M. Yager, Matthew Gregory Bursavich, Ashantai J. Yungai, Burt Richards, Paul L. Bartel, Daniel A. Wettstein
  • COMPOUNDS AND THERAPEUTIC USES THEREOF
    Publication number: 20120122840
    Abstract: The invention relates to compounds, pharmaceutical compositions, and uses thereof, including therapeutic uses thereof, such as methods useful for treating cancer.
    Type: Application
    Filed: September 23, 2011
    Publication date: May 17, 2012
    Applicant: Myrexis, Inc.
    Inventors: Dange Vijay Kumar, Ian A. McAlexander, Matthew Gregory Bursavich, Christophe Hoarau, Paul M. Slattum, David A. Gerrish, Jeffrey W. Lockman, Weston R. Judd, Michael Saunders, Daniel P. Parker, Daniel Feodore Zigar, In Chul Kim, J. Adam Willardsen, Kraig M. Yager, Mark D. Shenderovich, Brandi L. Williams, Keith D. Tardif
  • COMPOUNDS FOR TREATING VIRAL INFECTIONS
    Publication number: 20110144069
    Abstract: The invention relates to compounds, pharmaceutical compositions and methods useful for treating viral infection.
    Type: Application
    Filed: October 16, 2007
    Publication date: June 16, 2011
    Applicant: Myriad Genetics, Incorporated
    Inventors: Kraig M. Yager, Esther Arranz Plaza, Dange Vijay Kumar, In Chul Kim
  • COMPOUNDS AND THERAPEUTIC USES THEREOF
    Publication number: 20100240630
    Abstract: The invention relates to compounds, pharmaceutical compositions and methods useful for treating viral infection.
    Type: Application
    Filed: June 4, 2010
    Publication date: September 23, 2010
    Applicant: Myriad Pharmaceuticals, Inc..
    Inventors: Dange Vijay KUMAR, Kraig M. Yager, David A. Gerrish, Christophe Hoarau, Mark B. Anderson
  • PHARMACEUTICAL USES AND SYNTHESIS OF NICOTINANILIDE-N-OXIDES
    Publication number: 20100063105
    Abstract: Disclosed are nicotinanilide-N-oxide compounds, methods for their production, pharmaceutical compositions which include these compounds, and methods for their use in various therapies.
    Type: Application
    Filed: October 18, 2006
    Publication date: March 11, 2010
    Applicant: UCB SA
    Inventors: Neil S. Cutshall, Kraig M. Yager
  • ANTIVIRAL COMPOUNDS
    Publication number: 20090149429
    Abstract: The invention relates to compounds, pharmaceutical compositions and methods useful for treating viral infection.
    Type: Application
    Filed: June 22, 2006
    Publication date: June 11, 2009
    Applicant: Myriad Genetics, Incorporated
    Inventors: Esther Arranz Plaza, Kraig M. Yager, David Allen Gerrish, Mark B. Anderson, In Chul Kim, Dange Vijay Kumar
  • COMPOUNDS FOR TREATING VIRAL INFECTIONS
    Publication number: 20090105203
    Abstract: The invention relates to compounds, pharmaceutical compositions and methods useful for treating viral infection.
    Type: Application
    Filed: October 16, 2007
    Publication date: April 23, 2009
    Applicant: Myriad Genetics, Incorporated
    Inventors: Kraig M. Yager, Esther Arranz Plaza, Dange Vijay Kumar, In Chul Kim
  • COMPOUNDS FOR TREATING VIRAL INFECTIONS
    Publication number: 20080207573
    Abstract: The invention relates to compounds, pharmaceutical compositions and methods useful for treating viral infection.
    Type: Application
    Filed: May 7, 2008
    Publication date: August 28, 2008
    Applicant: Myriad Genetics, Incorporated
    Inventors: Kraig M. Yager, Esther Arranz Plaza, Dange Vijay Kumar, In Chul Kim
  • Anti-bacterial agents based upon oxoanion binding
    Patent number: 7326695
    Abstract: Compounds of the structure I: are useful for treating bacterial growth, wherein E is selected from the group consisting of B, P, and S, T1 and T2 are each independently selected from the group consisting of O, NR, and CH2, where R=H or C1-C8 alkyl, or C1-C8 oxoalkyl, and L is selected from the group consisting of ethylene, propylene, and four to six-membered alicyclic and aromatic rings, provided that structure I does not include AI-2-borate. The compounds may be used to treat bacterial infections in human beings and to regulate biofilm formation. Pharmaceutical compositions comprising one or more such compounds are useful for treating bacterial infections in human beings.
    Type: Grant
    Filed: May 17, 2006
    Date of Patent: February 5, 2008
    Assignee: The Trustees of Princeton University
    Inventors: Stephen R. Cooper, Kraig M. Yager
  • Pyrimidinecarboxamide derivatives and their use as anti-inflammatory agents
    Patent number: 7176310
    Abstract: This invention is directed to compound of the following formula (I): wherein R1, R2, R3 and R4 are as described herein. These compounds and pharmaceutical compositions containing the compounds are useful in treating inflammatory disorders in mammals.
    Type: Grant
    Filed: April 4, 2003
    Date of Patent: February 13, 2007
    Assignee: UCB SA
    Inventors: Theodore A. Baughman, Jim P. Boyce, Ihab S. Darwish, J. Jeffry Howbert, Nathan C. Ihle, Randy W. Jackson, Scott C. Jeffrey, Dean Maeda, Kraig M. Yager
  • Pharmaceutical uses and synthesis of nicotinanilide-N-oxides
    Patent number: 7141590
    Abstract: Disclosed are nicotinanilide-N-oxide compounds, methods for their production, pharmaceutical compositions which include these compounds, and methods for their use in various therapies.
    Type: Grant
    Filed: December 12, 2001
    Date of Patent: November 28, 2006
    Assignee: UCB SA
    Inventors: Neil S Cutshall, Kraig M Yager
  • Anti-bacterial agents based upon oxoanion binding
    Patent number: 7074776
    Abstract: Compounds of the structure I: are useful for treating bacterial growth, wherein E is selected from the group consisting of B, P, and S, T1 and T2 are each independently selected from the group consisting of O, NR, and CH2, where R?H or C1–C8 alkyl, or C1–C8 oxoalkyl, and L is selected from the group consisting of ethylene, propylene, and four to six-membered alicyclic and aromatic rings, provided that structure I does not include AI-2-borate. The compounds may be used to treat bacterial infections in human beings and to regulate biofilm formation. Pharmaceutical compositions comprising one or more such compounds are useful for treating bacterial infections in human beings.
    Type: Grant
    Filed: October 1, 2003
    Date of Patent: July 11, 2006
    Assignee: Quorex Pharmaceuticals, Inc.
    Inventors: Stephen R. Cooper, Kraig M. Yager
  • Anti-bacterial agents based upon oxoanion binding
    Publication number: 20040152669
    Abstract: Compounds of the structure I: 1
    Type: Application
    Filed: October 1, 2003
    Publication date: August 5, 2004
    Inventors: Stephen R. Cooper, Kraig M. Yager
  • Anti-bacterial agents based upon oxoanion binding
    Patent number: 6737415
    Abstract: Compounds of the structure I: are useful for treating bacterial growth, wherein E is selected from the group consisting of B, P, and S, T1, and T2 are each independently selected from the group consisting of O, NR, and CH2, where R=H or C1-C8 alkyl, or C1-C8 oxoalkyl, and L is selected from the group consisting of ethylene, propylene, and four to six-membered alicyclic and aromatic rings, provided that structure I does not include AI-2-borate. The compounds may be used to treat bacterial infections in human beings and to regulate biofilm formation. Pharmaceutical compositions comprising one or more such compounds are useful for treating bacterial infections in human beings.
    Type: Grant
    Filed: August 22, 2002
    Date of Patent: May 18, 2004
    Assignee: Quorex Pharmaceuticals, Inc.
    Inventors: Stephen R. Cooper, Kraig M. Yager