Abstract: Embodiments described herein relate generally to a system and methods for controlling and/or modifying the degradation behavior of degradable materials via a surface treatment and/or coating. This surface treatment and/or coating (also referred to herein as a “barrier”) can be used to modify the degradation profile without changing the bulk of the degradable material. The system includes a substrate that includes a degradable material and barrier configured to protect the substrate from a foreign environment. The barrier can include a conformal coating and/or a liquid impregnated surface engineered specifically to tailor the degradation profile of the underlying substrate. Optionally, a trigger mechanism can be used to further control and/or modify the degradation behavior of the substrate.