Patents by Inventor Krisana PEEWASAN

Krisana PEEWASAN has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • 2,4-diamino-6-ethylpyrimidine derivatives with antimalarial activities against
    Patent number: 11028072
    Abstract: The present invention relates to 2,4-diamino-6-ethylpyrimidine derivatives that are inhibitors of wild type and quadruple mutant dihydrofolate reductase (DHFR) of Plasmodium falciparum. They also show in vitro antimalarial activities against Plasmodium falciparum for both wild type and mutant that are comparable to or better than pyrimethamine. In addition, the compounds of the present invention show a good selectivity to Plasmodium falciparum and exhibit lower cytotoxicity than pyrimethamine.
    Type: Grant
    Filed: September 16, 2016
    Date of Patent: June 8, 2021
    Assignee: National Science and Technology Development Agency
    Inventors: Sumalee Kamchonwongpaisan, Netnapa Charoensetakul, Krisana Peewasan, Jarunee Vanichtanankul, Roonglawan Rattanajak, Supannee Taweechai, Tosapol Anukunwithaya, Aphisit Yoomuang, Yongyuth Yuthavong, Tirayut Vilaivan
  • 2,4-DIAMINO-6-ETHYLPYRIMIDINE DERIVATIVES WITH ANTIMALARIAL ACTIVITIES AGAINST PLASMODIUM FALCIPARUM
    Publication number: 20200239445
    Abstract: The present invention relates to 2,4-diamino-6-ethylpyrimidine derivatives that are inhibitors of wild type and quadruple mutant dihydrofolate reductase (DHFR) of Plasmodium falciparum. They also show in vitro antimalarial activities against Plasmodium falciparum for both wild type and mutant that are comparable to or better than pyrimethamine. In addition, the compounds of the present invention show a good selectivity to Plasmodium falciparum and exhibit lower cytotoxicity than pyrimethamine.
    Type: Application
    Filed: September 16, 2016
    Publication date: July 30, 2020
    Applicant: National Science and Technology Development Agency
    Inventors: Sumalee KAMCHONWONGPAISAN, Netnapa CHAROENSETAKUL, Krisana PEEWASAN, Jarunee VANICHTANANKUL, Roonglawan RATTANAJAK, Supannee TAWEECHAI, Tosapol ANUKUNWITHAYA, Aphisit YOOMUANG, Yongyuth YUTHAVONG, Tirayut VILAIVAN