Patents by Inventor Krishanu Ray

Krishanu Ray has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Polymorphic forms of Afatinib free base and Afatinib dimaleate
    Patent number: 11390612
    Abstract: The present invention relates to crystalline forms of Afatinib and its dimaleate salt. The present invention also relates to processes for the preparation of crystalline forms of Afatinib and its dimaleate salt. The present invention further relates to pharmaceutical compositions of such crystalline forms of Afatinib dimaleate and use thereof in the treatment of a patient in need thereof.
    Type: Grant
    Filed: October 1, 2020
    Date of Patent: July 19, 2022
    Assignee: Fresenius Kabi Oncology Ltd.
    Inventors: Walter Cabri, Saswata Lahiri, Bhuwan Bhaskar Mishra, Abul Azim, Nilendu Panda, Poli Reddy Bhavanam, Krishanu Ray, Nikunj Kachhadia, Kumber Singh
  • POLYMORPHIC FORMS OF AFATINIB FREE BASE AND AFATINIB DIMALEATE
    Publication number: 20210024506
    Abstract: The present invention relates to crystalline forms of Afatinib and its dimaleate salt. The present invention also relates to processes for the preparation of crystalline forms of Afatinib and its dimaleate salt. The present invention further relates to pharmaceutical compositions of such crystalline forms of Afatinib dimaleate and use thereof in the treatment of a patient in need thereof.
    Type: Application
    Filed: October 1, 2020
    Publication date: January 28, 2021
    Applicant: FRESENIUS KABI ONCOLOGY LIMITED
    Inventors: Walter CABRI, Saswata LAHIRI, Bhuwan Bhaskar MISHRA, Abul AZIM, Nilendu PANDA, Poli Reddy BHAVANAM, Krishanu RAY, Nikunj KACHHADIA, Kumber SINGH
  • Polymorphic forms of Afatinib free base and Afatinib dimaleate
    Patent number: 10800763
    Abstract: The present invention relates to crystalline forms of Afatinib and its dimaleate salt. The present invention also relates to processes for the preparation of crystalline forms of Afatinib and its dimaleate salt. The present invention further relates to pharmaceutical compositions of such crystalline forms of Afatinib dimaleate and use thereof in the treatment of a patient in need thereof.
    Type: Grant
    Filed: June 10, 2016
    Date of Patent: October 13, 2020
    Assignee: Fresenius Kabi Oncology Ltd.
    Inventors: Walter Cabri, Saswata Lahiri, Bhuwan Bhaskar Mishra, Abul Azim, Nilendu Panda, Poli Reddy Bhavanam, Krishanu Ray, Nikunj Kachhadia, Kumber Singh
  • POLYMORPHIC FORMS OF AFATINIB FREE BASE AND AFATINIB DIMALEATE
    Publication number: 20180312494
    Abstract: The present invention relates to crystalline forms of Afatinib and its dimaleate salt. The present invention also relates to processes for the preparation of crystalline forms of Afatinib and its dimaleate salt. The present invention further relates to pharmaceutical compositions of such crystalline forms of Afatinib dimaleate and use thereof in the treatment of a patient in need thereof.
    Type: Application
    Filed: June 10, 2016
    Publication date: November 1, 2018
    Applicant: FRESENIUS KABI ONCOLOGY LTD.
    Inventors: Walter CABRI, Saswata LAHIRI, Bhuwan Bhaskar MISHRA, Abul AZIM, Nilendu PANDA, Poli Reddy BHAVANAM, Krishanu RAY, Nikunj KACHHADIA, Kumber SINGH
  • BIOLOGICAL LASER PLASMA X-RAY POINT SOURCE
    Publication number: 20120228523
    Abstract: The invention provides targets coated with structured biological materials, which are employed in laser produced plasma systems. The biological materials selected from cells of microbial, protozoan or plankton origin are applied on a portion of a solid target, like polished glass plate which then form a target system that absorbs the intense laser pulses, generates hot dense plasma and results in the emission of the X-rays. The method of coating structured biomaterial decreases the usable laser intensity required for producing the hot plasma, while increasing the X-ray yield. The coatings are easy to prepare and it is possible to vary the nature and shape of the cellular material in order to control/regulate the interaction with the light and thereby optimize the resultant plasma generation and X-ray emission.
    Type: Application
    Filed: November 9, 2009
    Publication date: September 13, 2012
    Applicant: TATA INSTITUTE OF FUNDAMENTAL RESEARCH
    Inventors: Krishnamurthy Manchikanti, Krishanu Ray, Ravindra Kumar Gattamaraju
  • METAL-ENHANCED FLUORESCENCE FOR THE LABEL-FREE DETECTION OF INTERACTING BIOMOLECULES
    Publication number: 20100035335
    Abstract: A method for enhancing fluorescence of a biomolecule includes the step of associating the biomolecule having intrinsic fluorescence with a sensing surface that contains nanostructured metal. Association of the biomolecule with the nanostructured metal enhances its intrinsic fluorescence, which is detected upon exposure to electromagnetic radiation of a suitable wavelength. The sensing surface may include capture or ligand molecule which binds to the biomolecule and sequesters it in proximity to the nanostructured metal, thereby causing its fluorescent signal to be enhanced. The method can be used in label-free bioassays for detection of interacting biomolecules, such as antibody-antigen binding.
    Type: Application
    Filed: August 7, 2009
    Publication date: February 11, 2010
    Inventors: Joseph R. Lakowicz, Henryk Szmacinski, Krishanu Ray, Mustafa Habib Chowdhury, Kazimierz Nowaczyk