Patents by Inventor Krishna Das

Krishna Das has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Recombinant rhabdovirus encoding for a gasdermin
    Publication number: 20260117200
    Abstract: The present invention relates to the field of oncolytic viruses and in particular to a recombinant rhabdovirus, such as vesicular stomatitis virus encoding in its genome for a gasdermin. The invention is further directed to the use of the recombinant virus in the treatment of cancer and also to methods for producing such viruses.
    Type: Application
    Filed: December 18, 2024
    Publication date: April 30, 2026
    Inventors: Tobias NOLDEN, Krishna DAS, Sabrina SCHNEIDER, Theresa SCHWAIGER, Bart Gerrit SPIESSCHAERT
  • Heterologous Prime Boost Vaccine
    Publication number: 20250312428
    Abstract: The present invention pertains to the provision of a vaccine comprising a first component (K) and a second component (V), wherein the first component (K) comprises a complex in which a cell penetrating peptide, an antigenic domain and a TLR agonist are functionally linked and the second component (V) comprises an oncolytic recombinant vesicular stomatitis virus expressing an antigenic domain. The invention further pertains to the use of the inventive vaccine in the treatment of cancer. The invention also provides a recombinant vesicular stomatitis virus expressing an antigenic domain and its use in cancer vaccines.
    Type: Application
    Filed: June 13, 2025
    Publication date: October 9, 2025
    Inventors: Guido WOLLMANN, Krishna DAS, Madiha DEROUAZI, Elodie BELNOUE, Knut ELBERS
  • Heterologous Prime Boost Vaccine
    Publication number: 20220088162
    Abstract: The present invention pertains to the provision of a vaccine comprising a first component (K) and a second component (V), wherein the first component (K) comprises a complex in which a cell penetrating peptide, an antigenic domain and a TLR agonist are functionally linked and the second component (V) comprises an oncolytic recombinant vesicular stomatitis virus expressing an antigenic domain. The invention further pertains to the use of the inventive vaccine in the treatment of cancer. The invention also provides a recombinant vesicular stomatitis virus expressing an antigenic domain and its use in cancer vaccines.
    Type: Application
    Filed: September 14, 2021
    Publication date: March 24, 2022
    Inventors: Guido WOLLMANN, Krishna DAS, Madiha DEROUAZI, Elodie BELNOUE, Knut ELBERS
  • HERBAL COMPOSITION OF BLEND OF ACTIVE COMPONENTS PREPARED FROM MURRYA KOENIGII AND PIPER BETLE USEFUL FOR BLOCKING OF 5 LIPOXYGENASE ACTIVITY LEADING TO THE INHIBITION OF LEUKOTRIENE SYNTHESIS, SUPPRESSION OF INTERLEUKIN-4 PRODUCTION, AND ENHANCEMENT OF GAMMA INTERFERON RELEASE
    Patent number: 6773728
    Abstract: This invention relates to an herbal composition for the treatment and remedy of bronchial respiratory difficulties, more particularly this invention describes the process of separation, physicochemical characterization and biological response evaluation of active components obtained from extracts of any plant parts including leaves, barks, roots and seeds of plants M. koenigii and P. betle in order to establish their role on the treatment and remedy of bronchial respiratory troubles.
    Type: Grant
    Filed: November 1, 2001
    Date of Patent: August 10, 2004
    Assignee: Council of Scientific and Industrial Research
    Inventors: Santu Bandyopadhyay, Keshab Chandra Roy, Mitali Roy, Bikash Chandra Pal, Ranjan Bhadra, Krishna Das, Samir Bhattacharya
  • Herbal composition for treating asthma
    Patent number: 6746694
    Abstract: The invention relates to a novel composition containing an extract obtained from the plant Murraya koenigii and useful for the treatment or providing relief from acute asthma, and a process for the preparation of a lyophilized extract containing active principles of the plant Murraya koenigii, and a method for the treatment of asthma.
    Type: Grant
    Filed: October 2, 2000
    Date of Patent: June 8, 2004
    Assignee: Council of Scientific and Industrial Research
    Inventors: Ranjan Bhadra, Bikash Chandra Pal, Krishna Das, Samir Bhattacharaya
  • Herbal composition of blend of active components prepared from murrya koenigii and piper betle useful for blocking of 5 lipoxygenase activity leading to the inhibition of leukotriene synthesis, suppression of interleukin-4 production, and enhancement of gamma interferon release
    Publication number: 20020086068
    Abstract: This invention relates to an herbal composition for the treatment and remedy of bronchial respiratory difficulties, more particularly this invention describes the process of separation, physicochemical characterization and biological response evaluation of active components obtained from extracts of any plant parts including leaves, barks, roots and seeds of plants M. koenigii and P. betle in order to establish their role on the treatment and remedy of bronchial respiratory troubles.
    Type: Application
    Filed: November 1, 2001
    Publication date: July 4, 2002
    Inventors: Santu Bandyopadhyay, Keshab Chandra Roy, Mitali Roy, Bikash Chandra Pal, Ranjan Bhadra, Krishna Das, Samir Bhattacharya
  • Herbal formulation of a combination of Piper betel and Murrya koenigii extracts for blocking 5 lipoxygenase activity
    Patent number: 6413553
    Abstract: A pharmaceutical formulation is provided which is useful as a leukotrine synthesis and IL4 inhibitor and as a Th1 immunomodulator. The formulation comprises an effective amount of a combination of extracts and lyophilized extracts of Piper betel and Murrya koeniggi. The formulation can be formulated with pharmaceutically acceptable carriers. The formulation can be used in a method of treating humans for respiratory conditions.
    Type: Grant
    Filed: August 10, 2001
    Date of Patent: July 2, 2002
    Assignee: Council of Scientific and Industrial Research
    Inventors: Santu Bandyopadhyay, Keshab Chandra Roy, Mitali Roy, Bikash Chandra Pal, Ranjan Bhadra, Krishna Das, Samir Bhattacharaya