Patents by Inventor Krishna Mishra

Krishna Mishra has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Process for the manufacture of citalopram hydrobromide
    Publication number: 20060293530
    Abstract: The present invention describes an improved process for the preparation of pure 1-(4?-Fluorophenyl)-1-(3-dimethylaminopropyl)-5-phthalanecarbonitrile and its bromide salt (citalopram hydrobromide), which is a well known antidepressant. Another aspect of the invention is isolation of crystalline (4-Bromo-2-hydroxymethyl)phenyl-(4-fluorophenyl)-3-(dimethylaminopropyl)methanol (Bromodiol) and conversion of desmethylcitalopram which is formed during the cyanide exchange reaction, to citalopram by heating with a mixture of formaldehyde and formic acid in chloroform. The resulting citalopram is purified using conventionally extraction methodology.
    Type: Application
    Filed: April 28, 2006
    Publication date: December 28, 2006
    Applicant: Wockhardt Ltd.
    Inventors: Siddiqui Jaweed Mukarram, Bhargav Upadhye, Krishna Mishra, Mohammed Farooqui