Patents by Inventor Krishna Murthy Ella

Krishna Murthy Ella has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20130272999
    Abstract: A composition for treating a wound, wherein the composition can comprise therapeutically effective amount of an epidermal growth factor and a physiologically acceptable agent, wherein the physiologically acceptable agent comprises at least one of a stabilizer, a preservative, a thickening agent, carrier/diluent, and optionally pH regulating agent and humectant.
    Type: Application
    Filed: June 6, 2013
    Publication date: October 17, 2013
    Inventors: Krishna Murthy Ella, Srinivas Kannappa Vellimedu
  • Patent number: 8481049
    Abstract: A composition for treating a wound, wherein the composition can comprise therapeutically effective amount of an epidermal growth factor and a physiologically acceptable agent, wherein the physiologically acceptable agent comprises at least one of a stabilizer, a preservative, a thickening agent, carrier/diluent, and optionally pH regulating agent and humectant.
    Type: Grant
    Filed: May 18, 2006
    Date of Patent: July 9, 2013
    Assignee: Bharat Biotech International Limited
    Inventors: Krishna Murthy Ella, Srinivas Kannappa Vellimedu
  • Publication number: 20130022631
    Abstract: The present invention relates to vaccine formulation capable of eliciting protective immune response against Chikun-gunya virus infection in humans and other mammalian hosts. The immunogenic formulation comprises purified inactivated Chikun-gunya virus in a stable formulation. Methods of propagation and purification of the virus are discussed. The inactivated virus formulation is non-infectious, immunogenic and elicits protective immune response in mammalian host. The immunogenic composition is formulated for in vivo administration to humans. The invention also discusses the strategy of developing a subunit vaccine using the recombinant viral proteins as antigens for immunization. The recombinant virus antigens that are potentially immunogenic can be used in diagnosing for the presence of the virus.
    Type: Application
    Filed: August 31, 2007
    Publication date: January 24, 2013
    Inventors: Krishna Murthy Ella, Kandaswamy Sumathy, Jaya Sheela Pydigummala, Nagendra R. Hedge
  • Publication number: 20120269856
    Abstract: The invention describes a stable immunogenic protein having multiple cysteines molecules wherein the protein is having stability up to two years and purity more than 98% particularly rPvRII and/or rPfF2. It also discloses a method for producing said immunogenic protein comprising the following steps: culturing the host E.
    Type: Application
    Filed: July 23, 2009
    Publication date: October 25, 2012
    Applicant: BHARAT BIOTECH INTERNATIONAL LIMITED
    Inventors: Krishna Murthy Ella, Ganapathy Ravi
  • Publication number: 20100173842
    Abstract: The invention relates to a method of preparation and use of a polypeptide vaccine formulation for prevention and control of Staphylococci mediated infections in human, bovine and other mammals, using recombinant DNA technology.
    Type: Application
    Filed: October 8, 2009
    Publication date: July 8, 2010
    Applicant: BHARAT BIOTECH INTERNATIONAL LIMITED
    Inventors: Krishna Murthy ELLA, Kandaswamy SUMATHY, Krishna Mohan VADREVU
  • Publication number: 20100068227
    Abstract: The present invention relates to a composition comprising a viral antigen, a first protein and a second protein. Optionally, the composition also comprises three different disaccharaides, or, optionally, the composition comprises a primary sugar and at least one, preferably two secondary sugars. The present invention also relates to the use of a viral antigen, a first protein and a second protein for the manufacture of a composition, preferably a vaccine. The present invention furthermore relates to a method of treatment or prevention of virus associates diseases in humans. Moreover, the present invention relates to a method of adapting a virus to a suitable cell-line. The invention is also useful for the production of virus suspensions suitable for making stable, live/inactivated, monovalent and/or polyvalent, liquid/lyophilized rotavirus vaccine compositions for oral and/or nasal or any other suitable route of administration in human.
    Type: Application
    Filed: May 11, 2007
    Publication date: March 18, 2010
    Inventors: Krishna Murthy Ella, Victor Jerusha Augustus Harshavardhan Gutla, Krishna Mohan Vadrevu, Smita Suneel Singhania
  • Publication number: 20100015123
    Abstract: New thrombolytic protein molecules such as recombinant staphylokinase or streptokinase, urokinase, tissue plasminogen activator and the like, and suitable variants thereof, for targeting to brain tissue or any other tissue by either fusing to, or by synthesizing the candidate thrombolytic molecule(s) with a protein sequence comprising a strong amphipathic alpha helix containing protein transduction domain. Thrombolytic protein molecule(s) so engineered with the protein transduction domain is useful for enhanced uptake of such protein thrombolytic molecule(s) across the cell membranes and tissues including the blood brain barrier and find their use in the treatment of vascular thrombosis including cerebrovascular disorders caused by cerebral thrombosis or cerebral haemorrhage when used a as a therapeutic. The design and processes for cloning, expression, purification and protein transduction of such proteins across cell membranes.
    Type: Application
    Filed: May 11, 2007
    Publication date: January 21, 2010
    Applicant: BHARAT BIOTECH INTERNATIONAL LIMITED
    Inventors: Krishna Murthy Ella, Kandaswamy Sumathy
  • Publication number: 20090220538
    Abstract: The present invention describes method of preparation and use of polypeptide vaccine formulation for prevention and control of Staphylococci mediated infections in human, bovine and other mammals, using recombinant DNA technology.
    Type: Application
    Filed: July 13, 2006
    Publication date: September 3, 2009
    Applicant: BHARAT BIOTECH INTERNATIONAL LIMITED
    Inventors: Krishna Murthy Ella, Kandaswamy Sumathy, Krishna Mohan Vadrevu
  • Publication number: 20080311216
    Abstract: A composition for treating a wound, wherein the composition can comprise therapeutically effective amount of an epidermal growth factor and a physiologically acceptable agent, wherein the physiologically acceptable agent comprises at least one of a stabilizer, a preservative, a thickening agent, carrier/diluent, and optionally pH regulating agent and humectant.
    Type: Application
    Filed: May 18, 2006
    Publication date: December 18, 2008
    Applicant: BHARAT BIOTECH INTERNATIONAL LIMITED
    Inventors: Krishna Murthy Ella, Srinivas Kannappa Vellimedu
  • Publication number: 20080226614
    Abstract: The present invention describes a eukaryotic based synergistic formulation for gastro-intestinal disorders comprising eukaryolics and adjuncts selected from pharmaceutically and or physiologically acceptable components. The invention also describes the manner in which the eukaryolics are isolated from tropical fruits , The medium used for growing them and the method used to convert the formulation to dispensable forms. The medium comprising Glucose for carbon source, soybean casein dextrose medium (SCDM) for Nitrogen source, MgSo4, KCl, NaCl, (NH)4HPO4 and with microelements like MnSO4, FeSO4, Boric acid and Vitamins, D-Biotin and thiamine HCl ranging from 0.001% to 0.6% and designated as BBIL-SB. The formulation can be effectively used to prevent and or cure gastro intestinal disorders by administering in various forms to the mammals including human suffering there from, in a required quantity.
    Type: Application
    Filed: August 23, 2004
    Publication date: September 18, 2008
    Inventors: Krishna Murthy Ella, Srinivas Kannappa Vellimedu, Sivasankara Rao Sunkara