Patents by Inventor Krishna Yerramsetty

Krishna Yerramsetty has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Methods and systems for modeling of design representation in a library of editing cassettes
    Patent number: 11566241
    Abstract: Disclosed systems and methods relate to predicting the relative representation of genomic variants in an edited cell population, based on the editing cassette design representation in an editing cassette design library used to generate the edited cell population. A library of editing cassette designs is generated, and a feature vector, or sequence embedding, is developed for each design using natural language processing techniques. The feature vector may be based upon sequence attributes and editing kinetics of each cassette design as well as attributes that describe the library context. Features may include sequence embeddings generated from a neural network, linguistic-type distances, and statistical distance summaries thereof. The feature vectors are classified using one or more machine learning models, and the classified feature vectors are used to predict the representation of each design an edited cell population.
    Type: Grant
    Filed: October 1, 2021
    Date of Patent: January 31, 2023
    Assignee: Inscripta, Inc.
    Inventors: Andrea Halweg-Edwards, Thomas Hraha, Krishna Yerramsetty, Shea Lambert, Miles Gander, Matthew David Estes, Chad Douglas Sanada, Isaac David Wagner, Paul Hardenbol
  • GENOME-WIDE RATIONALLY-DESIGNED MUTATIONS LEADING TO ENHANCED LYSINE PRODUCTION IN E. COLI
    Publication number: 20210317402
    Abstract: The present disclosure relates to various different types of variants in E. coli coding and noncoding regions leading to enhanced lysine production for, e.g., supplements and nutraceuticals.
    Type: Application
    Filed: June 23, 2021
    Publication date: October 14, 2021
    Inventors: Eric Abbate, Katherine Krouse, Nandini Krishnamurthy, Richard Fox, Daniel Held, Michael Clay, Krishna Yerramsetty
  • Genome-wide rationally-designed mutations leading to enhanced lysine production in
    Patent number: 11078458
    Abstract: The present disclosure relates to various different types of variants in E. coli coding and noncoding regions leading to enhanced lysine production for, e.g., supplements and nutraceuticals.
    Type: Grant
    Filed: January 26, 2021
    Date of Patent: August 3, 2021
    Assignee: Inscripta, Inc.
    Inventors: Richard Fox, Daniel Held, Eric Abbate, Michael Clay, Katherine Krouse, Nandini Krishnamurthy, Krishna Yerramsetty
  • GENOME-WIDE RATIONALLY-DESIGNED MUTATIONS LEADING TO ENHANCED LYSINE PRODUCTION IN E. COLI
    Publication number: 20210155894
    Abstract: The present disclosure relates to various different types of variants in E. coli coding and noncoding regions leading to enhanced lysine production for, e.g., supplements and nutraceuticals.
    Type: Application
    Filed: January 26, 2021
    Publication date: May 27, 2021
    Inventors: Richard Fox, Daniel Held, Eric Abbate, Michael Clay, Katherine Krouse, Nandini Krishnamurthy, Krishna Yerramsetty
  • Genome-wide rationally-designed mutations leading to enhanced lysine production in
    Patent number: 10920189
    Abstract: The present disclosure relates to various different types of variants in E. coli coding and noncoding regions leading to enhanced lysine production for, e.g., supplements and nutraceuticals.
    Type: Grant
    Filed: June 18, 2020
    Date of Patent: February 16, 2021
    Assignee: Inscripta, Inc.
    Inventors: Richard Fox, Daniel Held, Eric Abbate, Michael Clay, Katherine Krouse, Nandini Krishnamurthy, Krishna Yerramsetty
  • GENOME-WIDE RATIONALLY-DESIGNED MUTATIONS LEADING TO ENHANCED LYSINE PRODUCTION IN E. COLI
    Publication number: 20200399586
    Abstract: The present disclosure relates to various different types of variants in E. coli coding and noncoding regions leading to enhanced lysine production for, e.g., supplements and nutraceuticals.
    Type: Application
    Filed: June 18, 2020
    Publication date: December 24, 2020
    Inventors: Richard Fox, Daniel Held, Eric Abbate, Michael Clay, Katherine Krouse, Nandini Krishnamurthy, Krishna Yerramsetty