Patents by Inventor KRISHNAMURTHY TOPPALADODDI

KRISHNAMURTHY TOPPALADODDI has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20230016551
    Abstract: The present invention provides the method and/or compositions for administering a therapeutically effective amount of ursodeoxycholic acid (UDCA) intravenously for the treatment and/or the prevention of liver diseases, preferably chronic liver diseases. The present invention also relates to methods of intravenous administration of UDCA in a dose of about 15 mg/kg to about 200 mg/ kg at a dosage interval of once every 12 hours to once every 72 hours.
    Type: Application
    Filed: January 21, 2021
    Publication date: January 19, 2023
    Applicant: SHILPA MEDICARE LTD
    Inventors: PALMIERI BENIAMINO, PRADEEP SHIVAKUMAR, KRISHNAMURTHY TOPPALADODDI
  • Patent number: 10682326
    Abstract: The present invention relates to a stable, non-aqueous liquid, formulation consisting essentially of melphalan, or a pharmaceutical acceptable salt thereof; and one or more solvents selected from group consisting of dimethyl acetamide, polyethylene glycol, ethanol, propylene glycol, dimethyl sulfoxide, N-methylpyrrolidone and glycerol; wherein said formulation is free of antioxidants, organic acid and added chloride ions; and the process for preparation thereof.
    Type: Grant
    Filed: July 17, 2019
    Date of Patent: June 16, 2020
    Assignee: SHILPA MEDICARE LIMITED
    Inventors: Shivakumar Pradeep, Krishnamurthy Toppaladoddi, Rizwan Ahmed, Guptha Chinni Guru Deva, Nagaraju Dasari
  • Patent number: 10583133
    Abstract: The present invention relates to a pharmaceutical composition comprising lenvatinib mesylate and a stabilizer in an amount of about 10% to about 20% based on the total weight of the composition, wherein the stabilizer is selected from the group consisting of calcium hydroxide and potassium hydroxide; and its process for preparation thereof.
    Type: Grant
    Filed: March 1, 2019
    Date of Patent: March 10, 2020
    Assignee: SHILPA MEDICARE LIMITED
    Inventors: Nijaguni Revansiddayya Rudraswamy Math, Sreenivas Reddy, Ravi Vamsi Peri, Krishnamurthy Toppaladoddi, Shivakumar Pradeep
  • Publication number: 20190275026
    Abstract: The present invention relates to a pharmaceutical composition comprising lenvatinib mesylate and a stabilizer in an amount of about 10% to about 20% based on the total weight of the composition, wherein the stabilizer is selected from the group consisting of calcium hydroxide and potassium hydroxide; and its process for preparation thereof.
    Type: Application
    Filed: March 1, 2019
    Publication date: September 12, 2019
    Applicant: SHILPA MEDICARE LTD
    Inventors: NIJAGUNI REVANSIDDAYYA RUDRASWAMY MATH, SREENIVAS REDDY, RAVI VAMSI PERI, KRISHNAMURTHY TOPPALADODDI, SHIVAKUMAR PRADEEP
  • Publication number: 20160143850
    Abstract: The invention relates to a granulate composition comprising 90-99.95% w/w of Imatinib mesylate, 0.05-0.2% w/w of binder and 0-8% w/w of disintegrant, wherein the granulate composition is prepared using binder in isopropyl alcohol solvent. The invention also relates to pharmaceutical compositions comprising Imatinib mesylate, with high polymorphic stability and processes for preparation thereof. Said granulate composition comprising 90-99.95% w/w of Imatinib mesylate and their pharmaceutical compositions derived may be useful in the treatment of cancer.
    Type: Application
    Filed: June 25, 2014
    Publication date: May 26, 2016
    Applicant: SHILPA MEDICARE LIMITED
    Inventors: PRADEEP SHIVAKUMAR, KRISHNAMURTHY TOPPALADODDI, SANJAY UMACHIGI, BADRINATH ALAMPALLI, AKSHAYKANT CHATURVEDI