Patents by Inventor Krishnaswami Raja

Krishnaswami Raja has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Clerodendrum viscosum and methods of use
    Patent number: 10059924
    Abstract: The present invention provides for a composition and formulations comprising an extract from Clerodendrum viscosum, and a method of obtaining the extract. The present invention also provides for a method of treating any disease where uncontrolled cellular proliferation occurs, such as cancers. In particular, the present invention provides a method for treating cervical cancer. The present invention also provides methods to inhibit proliferation and induce apoptosis of cancer cells.
    Type: Grant
    Filed: November 13, 2013
    Date of Patent: August 28, 2018
    Assignee: RESEARCH FOUNDATION OF THE CITY UNIVERSITY OF NEW YORK
    Inventors: Swami Nirmalananda Giri, Krishnaswami Raja, Jimmie Fata, Chong Sun, Rema Balambika, David Bolton
  • Curcumin derivatives
    Patent number: 9650404
    Abstract: The invention relates to novel curcumin derivatives in which one or two of the phenolic groups have been modified.
    Type: Grant
    Filed: February 25, 2011
    Date of Patent: May 16, 2017
    Assignee: RESEARCH FOUNDATION OF THE CITY UNIVERSITY OF NEW YORK
    Inventors: Krishnaswami Raja, Alejandra Alonso, Probal Banerjee, Sukanta Dolai, Christopher Corbo, Saadyah Averick, Amit Mogha, Shawon Debnath
  • Triterpene glycoside and triterpene compositions and methods of using same
    Patent number: 9643995
    Abstract: In the present invention, different strategies are used to improve the bioavailability of triterpene glycosides and triterpenes including, for example, (a) a covalent approach involving modification with polyethylene glycol and (b) a formulation approach involving non-covalent encapsulation in antibody targeted pol(DL-lactic acid) nanoparticles.
    Type: Grant
    Filed: January 17, 2014
    Date of Patent: May 9, 2017
    Assignee: RESEARCH FOUNDATION OF THE CITY UNIVERSITY OF NEW YORK
    Inventors: Linda Saxe Einbond, Krishnaswami Raja
  • Curcumin and tetrahydrocurcumin derivatives
    Patent number: 9447023
    Abstract: The invention relates to novel curcumin and tetrahydrocurcumin derivatives, which have been modified at one phenolic group to incorporate more-reactive groups. The curcumin and tetrahydrocurcumin derivatives are in the form of monomers, dimmers, and polymers.
    Type: Grant
    Filed: July 15, 2013
    Date of Patent: September 20, 2016
    Assignee: Research Foundation of the City University of New York
    Inventors: Krishnaswami Raja, Probal Banerjee, Andrew Auerbach, Wei Shi, William L'Amoreaux
  • Living copolymer-protein/peptide hybrids for biomedical applications
    Patent number: 9242010
    Abstract: Water soluble polymers having formula I: Y-(L1)n1-(C(O))n2—(R1)n3—R2 are claimed. The polymers may contain multiple water soluble, immunogenicity reducing moieties and multiple active moieties. The polymers may be linked to a protein, or a peptide having up to twelve amino acids.
    Type: Grant
    Filed: May 18, 2009
    Date of Patent: January 26, 2016
    Assignee: Research Foundation of The City University of New York
    Inventors: Krishnaswami Raja, Wei Shi, Sukanta Dolai, Saadyah Averick, William L'Amoreaux, Probal Banerjee
  • TRITERPENE GLYCOSIDE AND TRITERPENE COMPOSITIONS AND METHODS OF USING SAME
    Publication number: 20140199297
    Abstract: In the present invention, different strategies are used to improve the bioavailability of triterpene glycosides and triterpenes including, for example, (a) a covalent approach involving modification with polyethylene glycol and (b) a formulation approach involving non-covalent encapsulation in antibody targeted pol(DL-lactic acid) nanoparticles.
    Type: Application
    Filed: January 17, 2014
    Publication date: July 17, 2014
    Applicant: Research Foundation of the City University of New York
    Inventors: Linda Saxe Einbond, Krishnaswami Raja
  • Clerodendrum viscosum and Methods of Use
    Publication number: 20140134731
    Abstract: The present invention provides for a composition and formulations comprising an extract from Clerodendrum viscosum, and a method of obtaining the extract. The present invention also provides for a method of treating any disease where uncontrolled cellular proliferation occurs, such as cancers. In particular, the present invention provides a method for treating cervical cancer. The present invention also provides methods to inhibit proliferation and induce apoptosis of cancer cells.
    Type: Application
    Filed: November 13, 2013
    Publication date: May 15, 2014
    Applicant: The City University of New York
    Inventors: Swami Nirmalananda Giri, Krishnaswami Raja, Jimmie Fata, Chong Sun, Rema Balambika, David Bolton
  • Novel Curcumin and Tetrahydrocurcumin Derivatives
    Publication number: 20130296527
    Abstract: The invention relates to novel curcumin and tetrahydrocurcumin derivatives, which have been modified at one phenolic group to incorporate more-reactive groups. The curcumin and tetrahydrocurcumin derivatives are in the form of monomers, dimmers, and polymers.
    Type: Application
    Filed: July 15, 2013
    Publication date: November 7, 2013
    Applicant: Research Foundation of the City University of New York
    Inventors: Krishnaswami Raja, Probal Banerjee, Andrew Auerbach, Wei Shi, William L'Amoreaux
  • Curcumin Derivatives
    Publication number: 20130190256
    Abstract: The invention relates to novel curcumin derivatives in which one or two of the phenolic groups have been modified.
    Type: Application
    Filed: February 25, 2011
    Publication date: July 25, 2013
    Applicant: Research Foundation of the City University of New York
    Inventors: Krishnaswami Raja, Alejandra Alonso, Probal Banerjee, Sukanta Dolai, Christopher Corbo, Saadyah Averick, Amit Mogha, Shawon Debnath
  • Curcumin and tetrahydrocurcumin derivatives
    Patent number: 8487139
    Abstract: The invention relates to novel curcumin and tetrahydrocurcumin derivatives, which have been modified at one phenolic group to incorporate more-reactive groups. The curcumin and tetrahydrocurcumin derivatives are in the form of monomers, dimmers, and polymers.
    Type: Grant
    Filed: October 12, 2007
    Date of Patent: July 16, 2013
    Assignee: The Research Foundation of the City University of New York
    Inventors: Krishnaswami Raja, Probal Banerjee, Andrew Auerbach, Wei Shi, William L'Amoreaux
  • Living Copolymer-Protein/Peptide Hybrids for Biomedical Applications
    Publication number: 20110262991
    Abstract: Water soluble polymers having formula I: Y-(L1)ni-(C(O))n2—(R1)n3—R2 are claimed. The polymers may contain multiple water soluble, immunogenicity reducing moieties and multiple active moieties. The polymers may be linked to a protein, or a peptide having up to twelve amino acids.
    Type: Application
    Filed: May 18, 2009
    Publication date: October 27, 2011
    Inventors: Krishnaswami Raja, Wei Shi, Sukanta Dolai, Saadyah Averick, William L'Amoreaux, Probal Banerjee
  • Novel Curcumin and Tetrahydrocurcumin Derivatives
    Publication number: 20100240905
    Abstract: The invention relates to novel curcumin and tetrahydrocurcumin derivatives, which have been modified at one phenolic group to incorporate more-reactive groups. The curcumin and tetrahydrocurcumin derivatives are in the form of monomers, dimmers, and polymers.
    Type: Application
    Filed: October 12, 2007
    Publication date: September 23, 2010
    Applicant: RESEARCH FOUNDATION OF CITY UNIVERSITY OF NEW YORK
    Inventors: Krishnaswami Raja, Probal Banerjee, Andrew Auerbach, Wei Shi, William L'Amoreaux