Abstract: Embodiments of systems and methods for providing protocols for administering an aspect of care are presented. Specifically, certain embodiments relate to a sepsis diagnosis and management protocol which may have been segmented according to the severity of the sepsis, where the care directives provided by the differing segments of the protocol will be of differing intensity or invasiveness based upon the severity of the patient's disease. Embodiments of such protocols may be implemented in conjunction with computer systems to aid in providing that aspect of care in conjunction with a particular patient.