Patents by Inventor Kristen J Kelly

Kristen J Kelly has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 10287566
    Abstract: Methods of screening for dihydroxy-acid dehydratase (DHAD) variants that display increased DHAD activity are disclosed, along with DHAD variants identified by these methods. Such enzymes can result in increased production of compounds from DHAD requiring biosynthetic pathways. Also disclosed are isolated nucleic acids encoding the DHAD variants, recombinant host cells comprising the isolated nucleic acid molecules, and methods of producing butanol.
    Type: Grant
    Filed: January 16, 2017
    Date of Patent: May 14, 2019
    Assignee: Butamax Advanced Biofuels LLC
    Inventors: Kristen J. Kelly, Rick W. Ye
  • Publication number: 20170226497
    Abstract: Methods of screening for dihydroxy-acid dehydratase (DHAD) variants that display increased DHAD activity are disclosed, along with DHAD variants identified by these methods. Such enzymes can result in increased production of compounds from DHAD requiring biosynthetic pathways. Also disclosed are isolated nucleic acids encoding the DHAD variants, recombinant host cells comprising the isolated nucleic acid molecules, and methods of producing butanol.
    Type: Application
    Filed: January 16, 2017
    Publication date: August 10, 2017
    Inventors: Kristen J. Kelly, Rick W. YE
  • Patent number: 9580705
    Abstract: Methods of screening for dihydroxy-acid dehydratase (DHAD) variants that display increased DHAD activity are disclosed, along with DHAD variants identified by these methods. Such enzymes can result in increased production of compounds from DHAD requiring biosynthetic pathways. Also disclosed are isolated nucleic acids encoding the DHAD variants, recombinant host cells comprising the isolated nucleic acid molecules, and methods of producing butanol.
    Type: Grant
    Filed: March 13, 2014
    Date of Patent: February 28, 2017
    Assignee: Butamax Advanced Biofuels LLC
    Inventors: Kristen J. Kelly, Rick W. Ye
  • Patent number: 9371535
    Abstract: Specific polypeptides were identified as bacterial xylose isomerases that are able to provide xylose isomerase activity in yeast cells. The xylose isomerase activity can complete a xylose utilization pathway so that yeast can use xylose in fermentation, such as xylose in biomass hydrolysate.
    Type: Grant
    Filed: October 13, 2015
    Date of Patent: June 21, 2016
    Assignee: E I DU PONT DE NEMOURS AND COMPANY
    Inventors: Zhongqiang Chen, Kristen J Kelly, Rick W Ye
  • Publication number: 20160130590
    Abstract: Specific polypeptides were identified as bacterial xylose isomerases that are able to provide xylose isomerase activity in yeast cells. The xylose isomerase activity can complete a xylose utilization pathway so that yeast can use xylose in fermentation, such as xylose in biomass hydrolysate.
    Type: Application
    Filed: October 13, 2015
    Publication date: May 12, 2016
    Inventors: ZHONGQIANG CHEN, Kristen J Kelly, Rick W Ye
  • Patent number: 9187743
    Abstract: Specific polypeptides were identified as bacterial xylose isomerases that are able to provide xylose isomerase activity in yeast cells. The xylose isomerase activity can complete a xylose utilization pathway so that yeast can use xylose in fermentation, such as xylose in biomass hydrolysate.
    Type: Grant
    Filed: March 11, 2013
    Date of Patent: November 17, 2015
    Assignee: E I DU PONT DE NEMOURS AND COMPANY
    Inventors: Zhongqiang Chen, Kristen J Kelly, Rick W Ye
  • Patent number: 8906656
    Abstract: Polypeptides were identified among translated coding sequences from a metagenomic cow rumen database, that were shown to provide xylose isomerase activity in yeast cells. The xylose isomerase activity can complete a xylose utilization pathway so that yeast can use xylose in fermentation, such as xylose in biomass hydrolysate.
    Type: Grant
    Filed: January 16, 2014
    Date of Patent: December 9, 2014
    Assignee: E I du Pont de Nemours and Company
    Inventors: Zhongqiang Chen, Kristen J Kelly, Rick W Ye
  • Publication number: 20140273116
    Abstract: Methods of screening for dihydroxy-acid dehydratase (DHAD) variants that display increased DHAD activity are disclosed, along with DHAD variants identified by these methods. Such enzymes can result in increased production of compounds from DHAD requiring biosynthetic pathways. Also disclosed are isolated nucleic acids encoding the DHAD variants, recombinant host cells comprising the isolated nucleic acid molecules, and methods of producing butanol.
    Type: Application
    Filed: March 13, 2014
    Publication date: September 18, 2014
    Applicant: Butamax Advanced Biofuels LLC
    Inventors: Kristen J. Kelly, Rick W. Ye
  • Publication number: 20140256048
    Abstract: Specific polypeptides were identified as bacterial xylose isomerases that are able to provide xylose isomerase activity in yeast cells. The xylose isomerase activity can complete a xylose utilization pathway so that yeast can use xylose in fermentation, such as xylose in biomass hydrolysate.
    Type: Application
    Filed: March 11, 2013
    Publication date: September 11, 2014
    Applicant: E I Du Pont De Nemours And Company
    Inventors: ZHONGQIANG CHEN, Kristen J. Kelly, Rick W. Ye
  • Publication number: 20140256049
    Abstract: Polypeptides were identified among translated coding sequences from a metagenomic cow rumen database, that were shown to provide xylose isomerase activity in yeast cells. The xylose isomerase activity can complete a xylose utilization pathway so that yeast can use xylose in fermentation, such as xylose in biomass hydrolysate.
    Type: Application
    Filed: January 16, 2014
    Publication date: September 11, 2014
    Applicant: E I DU PONT DE NEMOURS AND COMPNAY
    Inventors: ZHONGQIANG CHEN, Kristen J. Kelly, Rick W. Ye
  • Patent number: 8669076
    Abstract: Polypeptides were identified among translated coding sequences from a metagenomic cow rumen database, that were shown to provide xylose isomerase activity in yeast cells. The xylose isomerase activity can complete a xylose utilization pathway so that yeast can use xylose in fermentation, such as xylose in biomass hydrolysate.
    Type: Grant
    Filed: March 11, 2013
    Date of Patent: March 11, 2014
    Assignee: E I du Pont de Nemours and Company
    Inventors: Zhongqiang Chen, Kristen J Kelly, Rick W Ye