Abstract: Wearable nystagmus detection devices are provided. The wearable device comprises first and second sensors configured to sense eye movement of the subject, and circuitry operably coupled to the sensors and configured to detect horizontal and vertical eye movements based on signals from the first and second sensors and/or a transmitter configured to transmit signals sensed by the first and second sensors to remote circuitry configured to receive signals transmitted by the transmitter and to detect horizontal and vertical eye movement based on signals from the first and second sensors. Also provided are systems and kits that include the devices, as well as methods for using devices and systems to monitor eye movement of a subject. The devices, systems, methods and kits find use in a variety of different applications.