Patents by Inventor Kristen M. Tummillo

Kristen M. Tummillo has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Autotransporter-mediated display of complement receptor ligands by bacterial immunogens
    Patent number: 11666647
    Abstract: An approach for modifying multiple types of bacteria to produce surface modifications that enhance the immunologic response when used as a vaccine. A series of plasmids (pYF, pYFC, pYFP, pSF, pSPF, and pSCF) may be used to transform bacteria which then produce surface-exposed ligands that bind to complement receptors on antigen presenting cells. When modified bacteria are used as a vaccine, the vaccine recipients produce significantly higher titers of specific antibodies and are better protected against challenges from the disease-causing bacteria.
    Type: Grant
    Filed: September 29, 2020
    Date of Patent: June 6, 2023
    Assignee: ALBANY MEDICAL COLLEGE
    Inventors: Karsten Hazlett, Kristen M. Tummillo, Edmund J. Gosselin
  • AUTOTRANSPORTER-MEDIATED DISPLAY OF COMPLEMENT RECEPTOR LIGANDS BY BACTERIAL IMMUNOGENS
    Publication number: 20220096618
    Abstract: An approach for modifying multiple types of bacteria to produce surface modifications that enhance the immunologic response when used as a vaccine. A series of plasmids (pYF, pYFC, pYFP, pSF, pSPF, and pSCF) may be used to transform bacteria which then produce surface-exposed ligands that bind to complement receptors on antigen presenting cells. When modified bacteria are used as a vaccine, the vaccine recipients produce significantly higher titers of specific antibodies and are better protected against challenges from the disease-causing bacteria.
    Type: Application
    Filed: September 29, 2020
    Publication date: March 31, 2022
    Applicant: ALBANY MEDICAL COLLEGE
    Inventors: Karsten Hazlett, Kristen M. Tummillo, Edmund J. Gosselin