Abstract: A method for secure data sharing includes creating uniform resource identifiers associated with a dataset. The method also includes generating and storing data access permissions for the dataset in an immutable decentralized ledger with a distributed ledger technology, creating a metadata describing the dataset and enabling access to the metadata via uniform resource identifiers, receiving a request from a client device to access a data subset associated with the dataset, verifying a digital credential of the client device using a secure authentication method, authorizing the request and confirming that the client device has a permission to access the dataset based on the distributed ledger technology, and providing multiple instructions and keys to the client device to access and retrieve the data subset. A system including a memory storing instructions and a processor configured to execute the instructions to cause the system to perform the above method are also provided.