Abstract: Methods for treating seizures caused by brain stimulation include providing a stimulator, programming the stimulator with one or more stimulation parameters configured to treat a medical condition, applying at least one stimulus with the stimulator to a stimulation site within the brain of a patient in accordance with the one or more stimulation parameters, and monitoring the patient for a seizure caused by the at least one stimulus.

Abstract: Methods of treating obesity and/or type II diabetes include applying at least one stimulus to the pituitary gland of a patient with an implanted stimulator in accordance with one or more stimulation parameters. The at least one stimulus is configured to treat obesity and/or type II diabetes. Systems for treating obesity and/or type II diabetes include a stimulator configured to apply at least one stimulus to the pituitary gland of a patient in accordance with one or more stimulation parameters. The at least one stimulus is configured to treat obesity and/or type II diabetes.

Abstract: Methods of treating a post-stroke disorder include applying at least one stimulus to a stimulation site within a patient with an implanted stimulator in accordance with one or more stimulation parameters. The stimulation site may include, for example, at least one or more of a motor cortex, thalamus, cerebellum, basal ganglia, globus pallidus, and periaqueductal gray. Systems for treating a post-stroke disorder include an implantable stimulator configured to apply at least one stimulus to a stimulation site within a patient in accordance with one or more stimulation parameters. The stimulation site may include, for example, at least one or more of a motor cortex, thalamus, cerebellum, basal ganglia, globus pallidus, and periaqueductal gray.

Abstract: A nerve stimulation lead has a distal end, a proximal end, and a longitudinal length. The nerve stimulation lead includes a plurality of electrodes disposed at the distal end, a plurality of terminals disposed at the proximal end, and a plurality of conductive wires electrically coupling the plurality of electrodes electrically to the plurality of terminals. The nerve stimulation lead also includes at least one anchoring unit disposed on the nerve stimulation lead. The at least one anchoring unit is configured and arranged for anchoring the nerve stimulation lead against a bony structure.

Abstract: An implantable device includes a device body and at least one anchoring unit configured and arranged for anchoring the device body in a patient upon implantation. The anchoring unit includes a resorbable material that resorbs into the patient over a period of time after implantation.

Abstract: A stimulation system is disclosed that may include a stimulator unit coupled to electrode contacts on a cuff. In one embodiment, the cuff may be placed at least partially around a nerve. The stimulation system may include at least two electrode contacts disposed on the cuff such that a distance between the at least two electrode contacts various along a length of the electrode contacts. In another embodiment, a plurality of electrode contacts are disposed on the cuff such that distances between at least one electrode contact within the plurality of electrode contacts and each electrode contact immediately adjacent to the at least one electrode contact are different. The stimulator unit may also be implantable.

Abstract: Methods and systems of facilitating stimulation of a stimulation site within a patient include implanting a distal portion of a stimulating member such that the distal portion of the stimulating member is in communication with a stimulation site located within a patient, securing the distal portion of the stimulating member at a first securing site with a first securing device, forming at least two curves of opposite concavity with a proximal portion of the stimulating member, securing the stimulating member at a second securing site with a second securing device, and coupling a proximal end of the stimulating member to a stimulator. In some examples, the at least two curves of opposite concavity are located in between the first and second securing devices.

Abstract: A system and method for introducing one or more stimulating drugs and/or applying electrical stimulation to the brain to treat mood and/or anxiety disorders uses an implantable system control unit (SCU), specifically an implantable signal/pulse generator (IPG) or microstimulator with one or more electrodes in the case of electrical stimulation, and an implantable pump with one or more catheters in the case of drug infusion. In cases requiring both electrical and drug stimulation, one or more SCUs are used. Alternatively and preferably, when needed, an SCU provides both electrical stimulation and one or more stimulating drugs. In a preferred embodiment, the system is capable of open- and closed-loop operation. In closed-loop operation, at least one SCU includes a sensor, and the sensed condition is used to adjust stimulation parameters.

Abstract: Methods of treating one or more effects of deafferentation within a patient include applying at least one stimulus to a stimulation site within the patient with an implanted stimulator in accordance with one or more stimulation parameters. The at least one stimulus is configured to treat one or more effects of deafferentation. Systems for treating one or more effects of deafferentation within a patient include a stimulator configured to apply at least one stimulus to a stimulation site within the patient in accordance with one or more stimulation parameters. The at least one stimulus is configured to treat one or more effects of deafferentation.

Abstract: Systems for adjusting a position of an implanted medical device within a patient include an engagement tool configured to couple to the implanted medical device. The engagement tool adjusts the position of the medical device when coupled to the implanted medical device. Methods of adjusting a position of an implanted medical device within a patient include locating the implanted medical device, coupling an engagement tool to the medical device, and adjusting a position of the engagement tool to adjust the position of the medical device.

Abstract: Systems and techniques for implanting medical devices. In one aspect, an apparatus includes a flexible base member that can be flexed manually to conform to a contour of an anatomy, the base member including a radioscopic indicium that has a characteristic such that, under radioscopic imaging, passage of a skin-penetrating electromagnetic radiation is hindered to an extent that is distinguishable from a hindrance of the electromagnetic radiation by another portion of the base member.

Abstract: Exemplary systems include a stimulator configured to be implanted within a patient, the stimulator having a body defined by at least one side surface disposed in between distal and proximal end surfaces, and a connector assembly configured to be coupled to the stimulator and extend parallel to the at least one side surface of the stimulator. The connector assembly is further configured to facilitate removable coupling of a lead having one or more electrodes disposed thereon to the stimulator.

Abstract: An implantable device includes an electrode lead body and at least one stimulating electrode contact disposed on or within the electrode lead body, the lead body being configured and arranged to be self anchoring within body tissue. In addition, the invention is directed to methods of making and using such self anchoring implantable devices.

Abstract: Methods of applying a stimulus to a stimulation site within the neck or head of a patient include implanting a distal portion of one or more leads adjacent to the stimulation site, forming a loop with a proximal portion of the one or more leads, and securing the distal and proximal portions of the one or more leads to one or more securing sites with one or more securing devices. The distal portion of the one or more leads includes a number of electrodes disposed thereon that are configured to deliver the stimulus to the stimulation site. Systems for applying a stimulus to a stimulation site within the neck or head of a patient include one or more leads having a number of electrodes disposed on a distal portion thereof and one or more securing devices configured to secure the one or more leads to one or more securing sites. The distal portion of the one or more leads is implanted adjacent to the stimulation site and the electrodes are configured to deliver the stimulus to the stimulation site.

Abstract: A nerve stimulation lead has a distal end, a proximal end, and a longitudinal length. The nerve stimulation lead includes a plurality of electrodes disposed at the distal end, a plurality of terminals disposed at the proximal end, and a plurality of conductive wires electrically coupling the plurality of electrodes electrically to the plurality of terminals. The nerve stimulation lead also includes at least one anchoring unit disposed on the nerve stimulation lead. The at least one anchoring unit is configured and arranged for anchoring the nerve stimulation lead against a bony structure.

Abstract: A lead anchor includes a plurality of parallel tubular members and at least one suture element configured and arranged for receiving a suture to suture the lead anchor to patient tissue. Each tubular member defines a lead lumen having a first opening and a second opening through which a lead can pass.

Abstract: An implantable member has a body with a distal end portion and either a fixation portion of the body disposed near the distal end portion or a fixation device attached to a tip of the distal end portion of the body. The fixation portion can include at least one surface feature of the body that facilitates fixation of the implantable member within tissue when implanted.

Abstract: A nerve stimulation lead has a distal end, a proximal end, and a longitudinal length. The nerve stimulation lead includes a plurality of electrodes disposed at the distal end, a plurality of terminals disposed at the proximal end, and a plurality of conductive wires electrically coupling the plurality of electrodes electrically to the plurality of terminals. The nerve stimulation lead also includes at least one anchoring unit disposed on the nerve stimulation lead. The at least one anchoring unit is configured and arranged for anchoring the nerve stimulation lead against a bony structure.

Abstract: Methods of facilitating stimulation of a stimulation site within a patient include implanting a distal portion of a first stimulating member such that the distal portion of the first stimulating member is in communication with a first stimulation site located within a patient, securing the distal portion of the first stimulating member at a first securing site with a first securing device positioned proximal to the first stimulation site, forming a first loop of at least 360 degrees with a portion of the first stimulating member proximal to the first securing device, securing the first loop with a second securing device at a second securing site having a position that is greater than or equal to substantially 180 degrees but less than or equal to substantially 315 degrees along the first loop from the first securing site, and positioning the second securing device and a stimulator to be coupled to a proximal end of the first stimulating member to maintain a curve in the first stimulating member of at least 45

Abstract: A system and method for introducing one or more stimulating drugs and/or applying electrical stimulation to the brain to treat mood and/or anxiety disorders uses an implantable system control unit (SCU), specifically an implantable signal/pulse generator (IPG) or microstimulator with one or more electrodes in the case of electrical stimulation, and an implantable pump with one or more catheters in the case of drug infusion. In cases requiring both electrical and drug stimulation, one or more SCUs are used. Alternatively and preferably, when needed, an SCU provides both electrical stimulation and one or more stimulating drugs. In a preferred embodiment, the system is capable of open- and closed-loop operation. In closed-loop operation, at least one SCU includes a sensor, and the sensed condition is used to adjust stimulation parameters.