Abstract: Disclosed herein are compositions and methods for treating, reducing or preventing oxidative stress in a subject. The compositions can be chewable confectionaries comprising a chewable base, one or more unprocessed phytochemical ingredients, and a sweetener comprising allulose. The unprocessed phytochemical ingredients can include ground plant materials selected from cinnamon, nutmeg, allspice, or combinations thereof. The chewable confectionary can exhibit a polyphenolic content of at least 100 ?g gallic acid equivalents (GAE) or greater, per gram of the chewable confectionary and an antioxidant capacity of at least 3,200 ?M Trolox equivalents per gram of the chewable confectionary, as determined by the oxygen radical absorbance (ORAC) assay. Kits, methods of making and using the chewable confectionary are also disclosed.

Abstract: Disclosed herein are compositions and methods for treating, reducing or preventing oxidative stress in a subject. The compositions can be chewable confectionaries comprising a chewable base, one or more unprocessed phytochemical ingredients, and a sweetener comprising allulose. The unprocessed phytochemical ingredients can include ground plant materials selected from cinnamon, nutmeg, allspice, or combinations thereof. The chewable confectionary can exhibit a polyphenolic content of at least 100 ?g gallic acid equivalents (GAE) or greater, per gram of the chewable confectionary and an antioxidant capacity of at least 3,200 ?M Trolox equivalents per gram of the chewable confectionary, as determined by the oxygen radical absorbance (ORAC) assay. Kits, methods of making and using the chewable confectionary are also disclosed.