Patents by Inventor Kristian Berg

Kristian Berg has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Photochemical internalization for delivery of molecules into the cytosol
    Publication number: 20050075268
    Abstract: The present invention provides a method for introducing a molecule into the cytosol of a cell in which the cell is contacted with a photosentistising agent, the cell is irradiated with light of a wavelength effective to activate the photosentisitising agent and, substantially at the same time or after the irradiation, the cell is contacted with the molecule to be introduced, particularly for use in cancer treatment, gene therapy and vaccination.
    Type: Application
    Filed: November 29, 2001
    Publication date: April 7, 2005
    Inventors: Kristian Berg, Lina Prasmickaite, Anders Hogset, Pal Selbo
  • Photochemical internalization for virus-mediated molecule delivery into the cyosol
    Publication number: 20040096425
    Abstract: The present invention provides a method for introducing a molecule into the cytosol of a cell in which the cell is contacted with a photosensitising agent, the cell is irradiated with light of a wavelength effective to activate the photosensitising agent and, substantially at the same time or after the irradiation, the cell is contacted with the molecule to be introduced, particularly for use in cancer treatment, gene therapy and vaccination.
    Type: Application
    Filed: November 28, 2003
    Publication date: May 20, 2004
    Inventors: Anders Hogset, Kristian Berg, Gunhild Mari Mlandsmo, Birgit Ovsteb?oslash; Engester, Lina Prasmickaite
  • Transfer of molecules into the cytosol of cells
    Patent number: 6680301
    Abstract: The present invention relates to a method for introducing molecules in cells by disrupting endosomal and lysosomal membranes using photodynamic treatment, without killing the majority of the cells by the photodynamic treatment. More particularly, this invention includes a method for transferring DNA and/or RNA, such as genes, to cells by photochemically inducing the disruption of endosomes and lysosomes.
    Type: Grant
    Filed: September 1, 1998
    Date of Patent: January 20, 2004
    Assignee: Photocure AS
    Inventors: Kristian Berg, Kirsten Sandvik, Johan Moan, Anders Høgset
  • Transfer of molecules into the cytosol of cells
    Publication number: 20030134813
    Abstract: The present invention relates to a method for introducing molecules in cells by disrupting endosomal and lysosomal membranes using photodynamic treatment, without killing the majority of the cells by the photodynamic treatment. More particularly, this invention includes a method for transferring DNA and/or RNA, such as genes, to cells by photochemically inducing the disruption of endosomes and lysosomes.
    Type: Application
    Filed: November 1, 2002
    Publication date: July 17, 2003
    Applicant: Photocure AS
    Inventors: Kristian Berg, Kirsten Sandvik, Johan Moan, Anders Hogset
  • TRANSFER OF MOLECULES INTO THE CYTOSOL OF CELLS
    Publication number: 20020155099
    Abstract: The present invention relates to a method for introducing molecules in cells by disrupting endosomal and lysosomal membranes using photodynamic treatment, without killing the majority of the cells by the photodynamic treatment. More particularly, this invention includes a method for transferring DNA and/or RNA, such as genes, to cells by photochemically inducing the disruption of endosomes and lysosomes.
    Type: Application
    Filed: September 1, 1998
    Publication date: October 24, 2002
    Inventors: KRISTIAN BERG, KIRSTEN SANDVIK, JOHAN MOAN, ANDERS HOGSET
  • Transfer of molecules into the cytosol of cells
    Patent number: 5876989
    Abstract: A method for releasing molecules into the cytosol of cells without killing the majority of the cells by allowing the molecules to be taken up in endosomes, lysosomes or other cell compartments and use light activation of photosensitizing compounds to rupture the membranes of the endosomes, lysosomes or other cell compartments, is described.
    Type: Grant
    Filed: March 28, 1997
    Date of Patent: March 2, 1999
    Assignee: Photocure AS
    Inventors: Kristian Berg, Kirsten Sandvig, Johan Moan