Patents by Inventor Kristian E. Baker

Kristian E. Baker has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • METHODS OF MODULATING NUCLEIC ACID STABILITY AND PROTEIN EXPRESSION
    Publication number: 20220259606
    Abstract: A synthetic nucleic acid which encodes a protein wherein at least one optimal or non-optimal codon in a wild type nucleic acid encoding the protein has been replaced respectively with one or more non-optimal codons or optimal codons encoding the same amino acid.
    Type: Application
    Filed: February 1, 2022
    Publication date: August 18, 2022
    Inventors: Jeffery M. Coller, Kristian E. Baker
  • Methods of modulating nucleic acid stability and protein expression
    Patent number: 11236345
    Abstract: A synthetic nucleic acid which encodes a protein wherein at least one optimal or non-optimal codon in a wild type nucleic acid encoding the protein has been replaced respectively with one or more non-optimal codons or optimal codons encoding the same amino acid.
    Type: Grant
    Filed: March 9, 2016
    Date of Patent: February 1, 2022
    Assignee: CASE WESTERN RESERVE UNIVERSITY
    Inventors: Jeffery M. Coller, Kristian E. Baker
  • Methods of modulating mRNA stability and protein expression
    Patent number: 10883109
    Abstract: A synthetic cDNA which encodes a protein wherein at least one optimal or non-optimal codon in a wild type DNA encoding the protein has been replaced respectively with one or more non-optimal codons or optimal codons encoding the same amino acid.
    Type: Grant
    Filed: September 22, 2017
    Date of Patent: January 5, 2021
    Assignee: CASE WESTERN RESERVE UNIVERSITY
    Inventors: Jeffery M. Coller, Kristian E. Baker
  • METHODS OF MODULATING mRNA STABILITY AND PROTEIN EXPRESSION
    Publication number: 20200140872
    Abstract: A synthetic cDNA which encodes a protein wherein at least one optimal or non-optimal codon in a wild type DNA encoding the protein has been replaced respectively with one or more non-optimal codons or optimal codons encoding the same amino acid.
    Type: Application
    Filed: September 22, 2017
    Publication date: May 7, 2020
    Inventors: Jeffery M. Coller, Kristian E. Baker
  • METHODS OF MODULATING mRNA STABILITY AND PROTEIN EXPRESSION
    Publication number: 20180135061
    Abstract: A synthetic cDNA which encodes a protein wherein at least one optimal or non-optimal codon in a wild type DNA encoding the protein has been replaced respectively with one or more non-optimal codons or optimal codons encoding the same amino acid.
    Type: Application
    Filed: September 22, 2017
    Publication date: May 17, 2018
    Inventors: Jeffery M. Coller, Kristian E. Baker
  • METHODS OF MODULATING NUCLEIC ACID STABILITY AND PROTEIN EXPRESSION
    Publication number: 20180112226
    Abstract: A synthetic nucleic acid which encodes a protein wherein at least one optimal or non-optimal codon in a wild type nucleic acid encoding the protein has been replaced respectively with one or more non-optimal codons or optimal codons encoding the same amino acid.
    Type: Application
    Filed: March 9, 2016
    Publication date: April 26, 2018
    Inventors: Jeffery M. Coller, Kristian E. Baker