Patents by Inventor Kristie Bridges

Kristie Bridges has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • NEUTRALIZING ANTIBODIES AGAINST GDF-8 AND USES THEREFOR
    Publication number: 20080044410
    Abstract: The disclosure provides novel antibodies against growth and differentiation factor-8 (GDF-8), in particular human antibodies, and antibody fragments, including those that inhibit GDF-8 activity in vitro and/or in vivo. The disclosure also provides methods for diagnosing, preventing, or treating degenerative disorders of muscle or bone, or disorders of insulin metabolism.
    Type: Application
    Filed: July 13, 2007
    Publication date: February 21, 2008
    Applicants: Wyeth, Cambridge Antibody Technology Limited
    Inventors: Geertruida Veldman, Monique Davies, Kening Song, Neil Wolfman, Kristie Bridges, Anne Field, Caroline Russell, Viia Valge-Archer
  • Structure-based approach to design of protein-processivity factor interactions
    Publication number: 20070055459
    Abstract: A method for the structure-based identification and selection of inhibitors of processivity factor binding to protein is disclosed herein. Characterization of the protein/processivity factor interface is given. Methods for the structure-based inhibition of processivity factor binding to protein are also given. One embodiment includes a class of peptidomimetics that mimic helical portions of proteins. In addition, methods of treatment of various diseases are given, using the inhibitors of the invention.
    Type: Application
    Filed: November 6, 2006
    Publication date: March 8, 2007
    Inventors: Donald Coen, James Hogle, Carl Elkin, Harmon Zuccola, Kristie Bridges, Scott Lokey