Abstract: This invention relates to genes identified from human chromosome 20p13-p12, which are associated with various diseases, including asthma. The invention also relates to the nucleotide sequences of these genes, isolated nucleic acids comprising these nucleotide sequences, and isolated polypeptides or peptides encoded thereby. The invention further relates to vectors and host cells comprising the disclosed nucleotide sequences, or fragments thereof, as well as antibodies that bind to the encoded polypeptides or peptides. Also related are ligands that modulate the activity of the disclosed genes or gene products. In addition, the invention relates to methods and compositions employing the disclosed nucleic acids, polypeptides or peptides, antibodies, and/or ligands for use in diagnostics and therapeutics for asthma and other diseases.

Abstract: The invention is an apparatus for use in serial radiography which provides replicable projection geometry between an energy source, an intraoral target area, and an image receptor. The device uses a biting surface bearing the impressions of a patient's tooth surfaces and an alignment arm which terminates in an alignment ring. The alignment ring is received by a sensor ring affixed to an x-ray source to provide proper projection geometry. Sensors in communication with electronic means may be disposed about the sensor ring to indicate proper alignment. The biting surface may comprise an acrylic stent or a platform supporting a quantity of an impressionable material.

Abstract: The invention is an apparatus for use in serial radiography which provides replicable projection geometry between an energy source, an intraoral target area, and an image receptor. The device uses a stent and an alignment arm which terminates in an alignment ring. The alignment ring is received by a sensor ring affixed to an x-ray source to provide proper projection geometry. Sensors in communication with electronic means may be disposed about the sensor ring to indicate proper alignment.