Patents by Inventor Kristin G. Beaumont
Kristin G. Beaumont has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 11801508Abstract: In biosciences and related fields, it can be useful to modify surfaces of apparatuses, devices, and materials that contact biomaterials such as biomolecules and biological micro-objects. Described herein are surface modifying and surface functionalizing reagents, preparation thereof, and methods for modifying surfaces to provide improved or altered performance with biomaterials.Type: GrantFiled: January 29, 2021Date of Patent: October 31, 2023Assignee: Berkeley Lights, Inc.Inventors: Randall D. Lowe, Jr., Alexander J. Mastroianni, Mark P. White, Gregory G. Lavieu, Kristin G. Beaumont
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Publication number: 20230182136Abstract: In situ-generated microfluidic isolation structures incorporating a solidified polymer network, methods of preparation and use, compositions and kits therefor are described. The ability to introduce in real time, a variety of isolating structures including pens and barriers offers improved methods of micro-object manipulation in microfluidic devices. The in situ-generated isolation structures may be permanently or temporarily installed.Type: ApplicationFiled: February 3, 2023Publication date: June 15, 2023Applicant: BERKELEY LIGHTS, INC.Inventors: Kristin G. Beaumont, Non-Linda Ding, Volker L.S. Kurz, Troy A. Lionberger, Randall D. Lowe, JR., Daniele Malleo, Andrew W. McFarland, J. Tanner Nevill, Xiaohua Wang
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Patent number: 11666913Abstract: In situ-generated microfluidic isolation structures incorporating a solidified polymer network, methods of preparation and use, compositions and kits therefor are described. The ability to introduce in real time, a variety of isolating structures including pens and barriers offers improved methods of micro-object manipulation in microfluidic devices. The in situ-generated isolation structures may be permanently or temporarily installed.Type: GrantFiled: November 22, 2016Date of Patent: June 6, 2023Assignee: BERKELEY LIGHTS, INCInventors: Kristin G. Beaumont, Nan-Linda Ding, Volker L. S. Kurz, Troy A. Lionberger, Randall D. Lowe, Jr., Daniele Malleo, Andrew W. McFarland, J. Tanner Nevill, Xiaohua Wang
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Publication number: 20230023831Abstract: In situ-generated microfluidic capture structures incorporating a solidified polymer network, methods of preparation and use, compositions and kits therefor are described. Microfluidic capture structures may be advantageously used for assays performed within the microfluidic environment, providing flexibility in assaying micro-objects such as biological cells. Assay reagents and analytes may be incorporated within the microfluidic capture structures.Type: ApplicationFiled: September 8, 2022Publication date: January 26, 2023Applicant: BERKLEY LIGHTS, INC.Inventors: Kristin G. BEAUMONT, Peter J. BEEMILLER, Volker L.S. KURZ, Gregory G. LAVIEU, Xiaohua WANG, Aathavan KARUNAKARAN
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Publication number: 20220356429Abstract: Systems, methods and kits are described for culturing one or more biological cells in a microfluidic device, including provision of nutrients and gaseous components configured to enhance cell growth, viability, portability, or any combination thereof. In some embodiments, culturing a single cell may produce a clonal population in the microfluidic device.Type: ApplicationFiled: May 12, 2022Publication date: November 10, 2022Inventors: Randall D. LOWE, JR., Kristin G. BEAUMONT, Aathavan KARUNAKARAN, Natalie C. MARKS, Jason M. MCEWEN, Mark P. WHITE, J. Tanner NEVILL, Gang F. WANG, Andrew W. MCFARLAND, Daniele Malleo, Keith J. BREINLINGER, Xiao GUAN, Kevin T. CHAPMAN
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Patent number: 11454629Abstract: In situ-generated microfluidic capture structures incorporating a solidified polymer network, methods of preparation and use, compositions and kits therefor are described. Microfluidic capture structures may be advantageously used for assays performed within the microfluidic environment, providing flexibility in assaying micro-objects such as biological cells. Assay reagents and analytes may be incorporated within the microfluidic capture structures.Type: GrantFiled: June 22, 2020Date of Patent: September 27, 2022Assignee: Berkeley Lights, Inc.Inventors: Kristin G. Beaumont, Peter J. Beemiller, Volker L. S. Kurz, Gregory G. Lavieu, Xiaohua Wang, Aathavan Karunakaran
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Patent number: 11365381Abstract: Systems, methods and kits are described for culturing one or more biological cells in a microfluidic device, including provision of nutrients and gaseous components configured to enhance cell growth, viability, portability, or any combination thereof. In some embodiments, culturing a single cell may produce a clonal population in the microfluidic device.Type: GrantFiled: July 2, 2020Date of Patent: June 21, 2022Assignee: Berkeley Lights, Inc.Inventors: Randall D. Lowe, Jr., Kristin G. Beaumont, Aathavan Karunakaran, Natalie C. Marks, Jason M. McEwen, Mark P. White, J. Tanner Nevill, Gang F. Wang, Andrew W. McFarland, Daniele Malleo, Keith J. Breinlinger, Xiao Guan, Kevin T. Chapman
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Publication number: 20210291171Abstract: In biosciences and related fields, it can be useful to modify surfaces of apparatuses, devices, and materials that contact biomaterials such as biomolecules and biological micro-objects. Described herein are surface modifying and surface functionalizing reagents, preparation thereof, and methods for modifying surfaces to provide improved or altered performance with biomaterials.Type: ApplicationFiled: January 29, 2021Publication date: September 23, 2021Applicant: Berkeley Lights, Inc.Inventors: Randall D. Lowe, JR., Alexander J. Mastroianni, Mark P. White, Gregory G. Lavieu, Kristin G. Beaumont
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Patent number: 11007520Abstract: In biosciences and related fields, it can be useful to modify surfaces of apparatuses, devices, and materials that contact biomaterials such as biomolecules and biological micro-objects. Described herein are surface modifying and surface functionalizing reagents, preparation thereof, and methods for modifying surfaces to provide improved or altered performance with biomaterials.Type: GrantFiled: November 20, 2018Date of Patent: May 18, 2021Assignee: Berkeley Lights, Inc.Inventors: Randall D. Lowe, Jr., Alexander J. Mastroianni, Mark P. White, Gregory G. Lavieu, Kristin G. Beaumont
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Publication number: 20210071124Abstract: Systems, methods and kits are described for culturing one or more biological cells in a microfluidic device, including provision of nutrients and gaseous components configured to enhance cell growth, viability, portability, or any combination thereof. In some embodiments, culturing a single cell may produce a clonal population in the microfluidic device.Type: ApplicationFiled: July 2, 2020Publication date: March 11, 2021Inventors: Randall D. LOWE, JR., Kristin G. BEAUMONT, Aathavan KARUNAKARAN, Natalie C. MARKS, Jason M. MCEWEN, Mark P. WHITE, J. Tanner NEVILL, Gang F. WANG, Andrew W. MCFARLAND, Daniele Malleo, Keith J. BREINLINGER, Xiao GUAN, Kevin T. CHAPMAN
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Publication number: 20210011015Abstract: In situ-generated microfluidic capture structures incorporating a solidified polymer network, methods of preparation and use, compositions and kits therefor are described. Microfluidic capture structures may be advantageously used for assays performed within the microfluidic environment, providing flexibility in assaying micro-objects such as biological cells. Assay reagents and analytes may be incorporated within the microfluidic capture structures.Type: ApplicationFiled: June 22, 2020Publication date: January 14, 2021Inventors: Kristin G. Beaumont, Peter J. Beemiller, Volker L.S. Kurz, Gregory G. Lavieu, Xiaohua Wang, Aathavan Karunakaran
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Patent number: 10705082Abstract: In situ-generated microfluidic capture structures incorporating a solidified polymer network, methods of preparation and use, compositions and kits therefor are described. Microfluidic capture structures may be advantageously used for assays performed within the microfluidic environment, providing flexibility in assaying micro-objects such as biological cells. Assay reagents and analytes may be incorporated within the microfluidic capture structures.Type: GrantFiled: December 7, 2016Date of Patent: July 7, 2020Assignee: Berkeley Lights, Inc.Inventors: Kristin G. Beaumont, Peter J. Beemiller, Volker L. S. Kurz, Gregory G. Lavieu, Xiaohua Wang, Aathavan Karunakaran
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Publication number: 20200115680Abstract: Methods of expanding T lymphocytes in a microfluidic device are provided. The methods can include introducing one or more T lymphocytes into a microfluidic device; contacting the one or more T lymphocytes with an activating agent; and perfusing culture medium through the microfluidic device for a period of time sufficient to allow the one or more T lymphocytes to undergo at least one round of mitotic cell division. The expansion can be non-specific or antigen-specific. T lymphocytes produced according to the disclosed methods are also provided, along with methods of treating cancer in a subject. The methods of treating cancer can include isolating T lymphocytes from a tissue sample obtained from the subject; expanding the isolated T lymphocytes in a microfluidic device; exporting the expanded T lymphocytes from the microfluidic device; and reintroducing the expanded T lymphocytes into the subject.Type: ApplicationFiled: July 19, 2019Publication date: April 16, 2020Applicant: Berkeley Lights, Inc.Inventors: Yelena Bronevetsky, Xiaohua Wang, Peter J. Beemiller, Kristin G. Beaumont, Randall D. Lowe, JR., Alexander J. Mastroianni, Kevin T. Chapman, Natalie C. Marks
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Publication number: 20190275516Abstract: In biosciences and related fields, it can be useful to modify surfaces of apparatuses, devices, and materials that contact biomaterials such as biomolecules and biological micro-objects. Described herein are surface modifying and surface functionalizing reagents, preparation thereof, and methods for modifying surfaces to provide improved or altered performance with biomaterials.Type: ApplicationFiled: November 20, 2018Publication date: September 12, 2019Applicant: Berkeley Lights, Inc.Inventors: Randall D. Lowe, JR., Alexander J. Mastroianni, Mark P. White, Gregory G. Lavieu, Kristin G. Beaumont
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Publication number: 20180135011Abstract: Methods of expanding T lymphocytes in a microfluidic device are provided. The methods can include introducing one or more T lymphocytes into a microfluidic device; contacting the one or more T lymphocytes with an activating agent; and perfusing culture medium through the microfluidic device for a period of time sufficient to allow the one or more T lymphocytes to undergo at least one round of mitotic cell division. The expansion can be non-specific or antigen-specific. T lymphocytes produced according to the disclosed methods are also provided, along with methods of treating cancer in a subject. The methods of treating cancer can include isolating T lymphocytes from a tissue sample obtained from the subject; expanding the isolated T lymphocytes in a microfluidic device; exporting the expanded T lymphocytes from the microfluidic device; and reintroducing the expanded T lymphocytes into the subject.Type: ApplicationFiled: November 2, 2017Publication date: May 17, 2018Inventors: Yelena Bronevetsky, Xiaohua Wang, Peter J. Beemiller, Kristin G. Beaumont, Randall D. Lowe, JR., Alexander J. Mastroianni, Kevin T. Chapman
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Publication number: 20170184583Abstract: In situ-generated microfluidic capture structures incorporating a solidified polymer network, methods of preparation and use, compositions and kits therefor are described. Microfluidic capture structures may be advantageously used for assays performed within the microfluidic environment, providing flexibility in assaying micro-objects such as biological cells. Assay reagents and analytes may be incorporated within the microfluidic capture structures.Type: ApplicationFiled: December 7, 2016Publication date: June 29, 2017Inventors: Kristin G. Beaumont, Peter J. Beemiller, Volker L.S. Kurz, Gregory G. Lavieu, Xiaohua Wang, Aathavan Karunakaran
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Publication number: 20170165667Abstract: In situ-generated microfluidic isolation structures incorporating a solidified polymer network, methods of preparation and use, compositions and kits therefor are described. The ability to introduce in real time, a variety of isolating structures including pens and barriers offers improved methods of micro-object manipulation in microfluidic devices. The in situ-generated isolation structures may be permanently or temporarily installed.Type: ApplicationFiled: November 22, 2016Publication date: June 15, 2017Inventors: Kristin G. Beaumont, Nan-Linda Ding, Volker L.S. Kurz, Troy A. Lionberger, Randall D. Lowe, Daniele Malleo, Andrew W. McFarland, J. Tanner Nevill, Xiaohua Wang