Patents by Inventor Kristin Janz

Kristin Janz has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • 4,6-diamino-[1,7]naphthyridine-3-carbonitrile inhibitors of Tpl2 kinase and methods of making and using the same
    Publication number: 20060276498
    Abstract: The present invention provides compounds of formula (I): and pharmaceutically acceptable salts thereof, wherein R1, R2, R3, R4, R5, R6, m and n are defined as described herein. The invention also provides methods of making the compounds of formula (I), and methods of treating inflammatory diseases, such as rheumatoid arthritis, in a mammal comprising administering a therapeutically effective amount of a compound of formula (I) to the mammal.
    Type: Application
    Filed: May 18, 2006
    Publication date: December 7, 2006
    Applicant: Wyeth
    Inventors: Neal Green, Lori Gavrin, Neelu Kaila, Yonghan Hu, Kristin Janz, Jennifer Thomason, Ariamala Gopalsamy, Steve Tam, Lih-Ling Lin, John Cuozzo, Dennis Powell
  • 3-Cyanoquinoline inhibitors of Tpl2 kinase and methods of making and using the same
    Publication number: 20060264460
    Abstract: The present invention provides compounds of formula (I): and pharmaceutically acceptable salts thereof, wherein R1, R2, R3, R4, R5, R6, R7, R8, m and n are defined as described herein. The invention also provides methods of making the compounds of formula (I), and methods of treating inflammatory diseases, such as rheumatoid arthritis, in a mammal comprising administering a therapeutically effective amount of a compound of formula (I) to the mammal.
    Type: Application
    Filed: May 18, 2006
    Publication date: November 23, 2006
    Applicant: Wyeth
    Inventors: Neal Green, Yonghan Hu, Neelu Kaila, Kristin Janz, Jennifer Thomason, Huan-Qiu Li, Rajeev Hotchandani, Junjun Wu, Ariamala Gopalsamy, Steve Tam, Lih-Ling Lin, John Cuozzo, Satenig Guler, Adrian Huang, Jeffrey condon
  • Methods and compositions for selectin inhibition
    Publication number: 20050101569
    Abstract: The present invention relates to the field of anti-inflammatory substances, and more particularly to novel compounds that act as antagonists of the mammalian adhesion proteins known as selectins. In some embodiments, methods for treating selectin mediated disorders are provided which include administration of compound of Formula I: wherein the constituent variables are defined herein.
    Type: Application
    Filed: November 9, 2004
    Publication date: May 12, 2005
    Applicant: Wyeth
    Inventors: Neelu Kaila, Silvano Debernardo, Kristin Janz, Raymond Camphausen, Patricia Bedard, Adrian Huang
  • Methods and compositions for selectin inhibition
    Publication number: 20050101568
    Abstract: The present invention relates to the field of anti-inflammatory substances, and more particularly to novel compounds that act as antagonists of the mammalian adhesion proteins known as selectins. In some embodiments, methods for treating selectin mediated disorders are provided which include administration of compound of Formula I: wherein the constituent variables are defined herein.
    Type: Application
    Filed: November 9, 2004
    Publication date: May 12, 2005
    Applicant: Wyeth
    Inventors: Neelu Kaila, Silvano Debernardo, Kristin Janz, Raymond Camphausen, Patricia Bedard