Patents by Inventor Kristin M. Bompiani

Kristin M. Bompiani has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Aptamers to glycoprotein VI
    Patent number: 9061043
    Abstract: The present invention relates, in general, to glycoprotein VI (GPVI) and, in particular, to aptamers to GPVI and to compositions comprising same. The invention also relates to methods of inhibiting platelet aggregation using an aptamer that binds to and inhibits the activity of GPVI. The invention further relates to antidotes to GPVI aptamers and to methods of using such antidotes to reverse aptamer-induced platelet inhibition. The invention also relates to aptamers that bind to and enhance the activity of GPVI.
    Type: Grant
    Filed: October 13, 2011
    Date of Patent: June 23, 2015
    Assignee: DUKE UNIVERSITY
    Inventors: Bruce A. Sullenger, Kristin M. Bompiani
  • APTAMERS TO GLYCOPROTEIN VI
    Publication number: 20130210903
    Abstract: The present invention relates, in general, to glycoprotein VI (GPVI) and, in particular, to aptamers to GPVI and to compositions comprising same. The invention also relates to methods of inhibiting platelet aggregation using an aptamer that binds to and inhibits the activity of GPVI. The invention further relates to antidotes to GPVI aptamers and to methods of using such antidotes to reverse aptamer-induced platelet inhibition. The invention also relates to aptamers that bind to and enhance the activity of GPVI.
    Type: Application
    Filed: October 13, 2011
    Publication date: August 15, 2013
    Applicant: Duke University
    Inventors: Bruce A. Sullenger, Kristin M. Bompiani