Abstract: A tool, method, and system for assessing an incremental value of one or more items in an item assortment are disclosed. The tool can receive historical purchasing data, which can include a plurality of customers purchasing one or more items of a plurality of items in an item assortment. The tool can use the historical purchasing data for the plurality of customers to simulate execution of removal of an item from the item assortment, wherein removal of the item from the item assortment causes an incremental loss associated with the item. The tool can order any number of items of the historical purchasing data. The tool can execute scenario simulations, and the tool can account for probabilities when interacting with the historical purchasing data. The tool can display assessment data and receive inputs via an interactive user interface. The tool can launch the assessment data in a downstream application.

Abstract: A novel gene, PB39, that is up-regulated, or over-expressed, in prostate cancer has been identified. The gene has been identified by means of its cDNA obtained by reverse transcription of the corresponding mRNA. Microdissection of prostate glands that had been surgically removed from prostate cancer patients revealed a novel up-regulated transcript in an aggressive prostate carcinoma. Differential analysis for the presence of this gene was carried out from the same glands by comparing transcription in microdissected normal prostatic epithelium versus that in microdissected invasive tumor. The transcript was over-expressed in 5 of 10 prostate carcinomas examined. A variant transcript was over-expressed in 4 of 4 prostate carcinomas, and was found in 1 of 4 normal samples.

Abstract: A novel gene, PB39, that is up-regulated, or over-expressed, in prostate cancer has been identified. The gene has been identified by means of its cDNA obtained by reverse transcription of the corresponding mRNA. Microdissection of prostate glands that had been surgically removed from prostate cancer patients revealed a novel up-regulated transcript in an aggressive prostate carcinoma. Differential analysis for the presence of this gene was carried out from the same glands by comparing tanscription in microdissected normal prostatic epithelium versus that in microdissected invasive tumor. The transcript was over-expressed in 5 of 10 prostate carcinomas examined. A variant transcript was over-expressed in 4 of 4 prostate carcinomas, and was found in 1 of 4 normal samples.