Patents by Inventor Kristina Gruden

Kristina Gruden has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20220254451
    Abstract: A method of storing information in nucleic acid includes processing units of information into permutation numbers by a reversible algorithm, providing a library of n distinct oligonucleotide strings of predetermined length in a fixed order, n being a positive integer and each distinct oligonucleotide string associated with a distinct index indicating the ordinal position, assembling distinct oligonucleotide strings to create strands comprising at least two oligonucleotide strings, each oligonucleotide string's ordinal position matching with a permutation number, each strand including at least a data bearing part and a semantic part, and the semantic part to allocate orientation and/or order to a strand.
    Type: Application
    Filed: November 7, 2019
    Publication date: August 11, 2022
    Inventors: Klemen Zupancic, Nejc Bernot, Zan Pirc, Jasna Lalic, Kristina Gruden, Urska Cepin, Blaz Nemec, Luka Zupancic
  • Patent number: 10913985
    Abstract: The present invention relates in general to the field of recombinant protein expression. In particular, the present invention relates to a method for selecting a suitable candidate cell clone for recombinant protein expression and to a host cell for recombinant protein expression, the host cell exhibiting artificially modified gene expression of at least one gene selected from the group consisting of: Fkbp10, ZdhhC6, Myrip, Actc1, AC124993.19, Runx2, AC158560.4, PlekhB1, Rps6KA2, Sept1, Sprr2k, and Flt1.
    Type: Grant
    Filed: November 12, 2015
    Date of Patent: February 9, 2021
    Assignee: Lek Pharmaceuticals d.d.
    Inventors: Uro{hacek over (s)} Jamnikar, Marjanca Blas, Kristina Gruden
  • Patent number: 10913984
    Abstract: The present invention relates in general to the field of recombinant protein expression. In particular, the present invention relates to a method for selecting a suitable candidate cell clone for recombinant protein expression and to a host cell for recombinant protein expression, the host cell exhibiting artificially modified gene expression of at least one gene selected from the group consisting of: Hist1h2bc, Egrl, BX842664.2/Hist 1h3c, Dhfr, Fgfr2, AC115880.11, Mmp10, Vsnll (optional), CU459186.17, El 30203 B14Rik, Cspg4, C1qtnf1, Foxp2, and Ptpre.
    Type: Grant
    Filed: November 12, 2015
    Date of Patent: February 9, 2021
    Assignee: Lek Pharmaceuticals d.d.
    Inventors: Uro{hacek over (s)} Jamnikar, Kristina Gruden
  • Publication number: 20170321288
    Abstract: The present invention relates in general to the field of recombinant protein expression. In particular, the present invention relates to a method for selecting a suitable candidate cell clone for recombinant protein expression and to a host cell for recombinant protein expression, the host cell exhibiting artificially modified gene expression of at least one gene selected from the group consisting of: Fkbp10, ZdhhC6, Myrip, Actc1, AC124993.19, Runx2, AC158560.4, PlekhB1, Rps6KA2, Sept1, Sprr2k, and Flt1.
    Type: Application
    Filed: November 12, 2015
    Publication date: November 9, 2017
    Applicant: Lek Pharmaceuticals d.d.
    Inventors: Uros Jamnikar, Marjanca Blas, Kristina Gruden
  • Publication number: 20170314082
    Abstract: The present invention relates in general to the field of recombinant protein expression. In particular, the present invention relates to a method for selecting a suitable candidate cell clone for recombinant protein expression and to a host cell for recombinant protein expression, the host cell exhibiting artificially modified gene expression of at least one gene selected from the group consisting of: Hist1h2bc, Egrl, BX842664.2/Hist 1h3c, Dhfr, Fgfr2, AC115880.11, Mmp10, Vsnll (optional), CU459186.17, El 30203 B14Rik, Cspg4, C1qtnf1, Foxp2, and Ptpre.
    Type: Application
    Filed: November 12, 2015
    Publication date: November 2, 2017
    Applicant: Lek Pharmaceuticals d.d.
    Inventors: Uros Jamnikar, Kristina Gruden
  • Patent number: 6861578
    Abstract: A method of protecting a plant or part of a plant from insect or nematode infestation is disclosed herein. The method includes the steps of: inserting into the genome of cells or tissue from a plant a sequence coding for equistatin operably linked to a promoter sequence active in the plant to cause expression of the protein at levels which provide an insect or nematode controlling amount of the protein; and regenerating resistant whole plants from the cells or tissue. Also disclosed is a transgenic plant or its sexual progeny which is resistant to attack by one or more insects or nematodes having digestive cysteine proteases. Also disclosed is an expression vehicle that includes a promotor effective to promote expression of a downstream coding sequence in plant cells, the expression vehicle being effective to express in plant cells insect controlling amounts of equistatin.
    Type: Grant
    Filed: June 18, 1998
    Date of Patent: March 1, 2005
    Assignee: Plant Research International B.V.
    Inventors: Maarten Anthonie Jongsma, Borut Strukelj, Brigita Lenarcic, Kristina Gruden, Vito Turk, Hendrik J. Bosch, Willem Johannes Stiekema