Patents by Inventor Kristina KRIKSCIUKAITE

Kristina KRIKSCIUKAITE has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • SSTR-TARGETED CONJUGATES AND FORMULATIONS THEREOF
    Publication number: 20220257766
    Abstract: Conjugates of an active agent such as DM1 attached to a targeting moiety, such as a somatostatin receptor binding moiety, via a linker, have been designed. Such conjugates can provide improved temporospatial delivery of the active agent, improved biodistribution and penetration in tumor, and/or decreased toxicity. Methods of making the conjugates and the formulations thereof are provided. Methods of administering the formulations to a subject in need thereof are provided, for example, to treat or prevent cancer.
    Type: Application
    Filed: June 24, 2020
    Publication date: August 18, 2022
    Inventors: Eugene ZHOROV, Christopher SEARS, Jeffrey BLOSS, Richard WOOSTER, Kristina KRIKSCIUKAITE
  • HSP90-BINDING CONJUGATES AND COMBINATION THERAPIES THEREOF
    Publication number: 20220257777
    Abstract: The disclosure generally relates to a method of treating cancer comprising administering HSP90-binding conjugates or administering two distinct therapeutic agents as a combination therapy. Components of the combination therapy and methods of using the combination therapy are provided.
    Type: Application
    Filed: June 24, 2020
    Publication date: August 18, 2022
    Inventors: Jeffrey BLOSS, Samantha PERINO, James M. QUINN, Kerry WHALEN, Richard WOOSTER, Kristina KRIKSCIUKAITE, Laura E. MEI, Mark T. BILODEAU