Patents by Inventor Kristina Y. AGUILERA

Kristina Y. AGUILERA has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Small-molecule inhibitors targeting discoidin domain receptor 1 and uses thereof
    Patent number: 10370360
    Abstract: Compounds of formula (I), their pharmaceutically acceptable salts and stereoisomers thereof, as well as application in effectively inhibiting the enzymatic activity of discoidin domain receptor 1 and can be used as new therapeutic agents for preventing and treating e.g. inflammation, liver fibrosis, kidney fibrosis, lung fibrosis, skin scar, atherosclerosis, and cancer. The compound of formula I is: wherein the variables are as defined herein.
    Type: Grant
    Filed: October 21, 2015
    Date of Patent: August 6, 2019
    Assignees: The Board of Regents of the University of Texas System, Guangzhou Institutes of Biomedicine and Health, Chinese Academy of Sciences
    Inventors: Rolf A. Brekken, Ke Ding, Xiaomei Ren, Zhengchao Tu, Zhen Wang, Kristina Y. Aguilera
  • SMALL-MOLECULE INHIBITORS TARGETING DISCOIDIN DOMAIN RECEPTOR 1 AND USES THEREOF
    Publication number: 20180022730
    Abstract: Compounds of formula (I), their pharmaceutically acceptable salts and stereoisomers thereof, as well as application in effectively inhibiting the enzymatic activity of discoidin domain receptor 1 and can be used as new therapeutic agents for preventing and treating e.g. inflammation, liver fibrosis, kidney fibrosis, lung fibrosis, skin scar, atherosclerosis, and cancer. The compound of formula I is: wherein the variables are as defined herein.
    Type: Application
    Filed: October 21, 2015
    Publication date: January 25, 2018
    Inventors: Rolf A. BREKKEN, Ke DING, Xiaomei REN, Zhengchao TU, Zhen WANG, Kristina Y. AGUILERA