Patents by Inventor Kristopher Scott Buchanan
Kristopher Scott Buchanan has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 11957465Abstract: Apparatuses, methods, and systems are disclosed for accelerated ergonomic collection of capillary blood. An apparatus and system include a blood collection module with a proximal portion including a vacuum generation chamber, a distal portion including a blood collection chamber, a concave mid portion including a pressure equalization channel configured to equalize reduced air pressure. The apparatus further includes a sealing surface to stably seal the blood collection module to the skin around a collection site and a slide latch actuated by a lengthwise sliding motion. Also included is a lancet carrier with linearly-arranged lancet strips to puncture rows of blood extraction slits in the collection site. The apparatus also includes an angled transfer port with a low-resistance non-microfluidic blood flow channel to a transfer module, then to a plasma separation module with a multilayer laminate and plasma separation membrane. Methods for accelerated ergonomic collection of capillary blood are disclosed.Type: GrantFiled: February 16, 2023Date of Patent: April 16, 2024Assignee: RedDrop Dx, Inc.Inventors: Kristopher Scott Buchanan, William Kristopher Buchanan, Dirk van den Boom, Thomas Michael Johannsen, Wesley Joseph Hager, Matthew Bryan Huntingdon, Christopher Andrew Frankson, Landon Bruggeman
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Publication number: 20240065589Abstract: Apparatuses, methods, and systems are disclosed for accelerated ergonomic collection of capillary blood. An apparatus and system include a blood collection module with a proximal portion including a vacuum generation chamber, a distal portion including a blood collection chamber, a concave mid portion including a pressure equalization channel configured to equalize reduced air pressure. The apparatus further includes a sealing surface to stably seal the blood collection module to the skin around a collection site and a slide latch actuated by a lengthwise sliding motion. Also included is a lancet carrier with linearly-arranged lancet strips to puncture rows of blood extraction slits in the collection site. The apparatus also includes an angled transfer port with a low-resistance non-microfluidic blood flow channel to a transfer module, then to a plasma separation module with a multilayer laminate and plasma separation membrane. Methods for accelerated ergonomic collection of capillary blood are disclosed.Type: ApplicationFiled: February 16, 2023Publication date: February 29, 2024Inventors: Kristopher Scott Buchanan, William Kristopher Buchanan, Dirk van den Boom, Thomas Michael Johannsen, Wesley Joseph Hager, Matthew Bryan Huntingdon, Christopher Andrew Frankson, Landon Bruggeman
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Publication number: 20230077773Abstract: A microfluidic chip having a micro channel for processing a sample is provided. The micro channel may focus the sample by using focusing fluid and a core stream forming geometry. The core stream forming geometry may include a lateral fluid focusing component and one or more vertical fluid focusing components. A microfluidic chip may include a plurality micro channels operating in parallel on a microfluidic chip.Type: ApplicationFiled: September 14, 2022Publication date: March 16, 2023Inventors: Erin Koksal, Johnathan Charles Sharpe, Kristopher Scott Buchanan, Blair D. Morad
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Publication number: 20220380752Abstract: Provided herein are devices and methods for extracting blood plasma from ultra-low volumes of blood. In some cases, the devices and methods use positive pressure to force a blood sample through a filter or a membrane. In some cases, the devices and methods use centrifugation to force a blood sample through a filter or a membrane. The devices and methods disclosed herein are suitable for the preparation of high-quality samples containing cell-free nucleic acids.Type: ApplicationFiled: May 25, 2022Publication date: December 1, 2022Inventors: Dirk van den Boom, Mathias Ehrich, Michael Van Nguyen, Christopher Ellison, Jeffery William Domenighini, Dylann Duncan Ceriani, Kristopher Scott Buchanan, Michael Gordon Smith
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Patent number: 11446665Abstract: A microfluidic chip having a micro channel for processing a sample is provided. The micro channel may focus the sample by using focusing fluid and a core stream forming geometry. The core stream forming geometry may include a lateral fluid focusing component and one or more vertical fluid focusing components. A microfluidic chip may include a plurality micro channels operating in parallel on a microfluidic chip.Type: GrantFiled: March 9, 2020Date of Patent: September 20, 2022Assignee: CYTONOME/ST, LLCInventors: Erin Koksal, Johnathan Charles Sharpe, Kristopher Scott Buchanan, Blair D. Morad
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Patent number: 10870175Abstract: Microfluidic flow-through elements and methods for forming and using the same, particularly, low cost, easily sterilized, disposable microfluidic flow-through elements may include an orifice region suitable, for example, for fluid jet formation (such as in a droplet sorter or flow cell) or sample injection or hydrodynamic focusing (such as in a non-droplet flow cytometer). Laser drilling, for example laser ablation, may be used to form an orifice region extending through an orifice wall section of a base substrate. The base substrate may be unitarily-formed by injection molding a polymeric material. The orifice region may be advantageously configured to form a predetermined geometry by controlling the characteristics of the ablating beam.Type: GrantFiled: September 18, 2014Date of Patent: December 22, 2020Assignee: CYTONOME/ST, LLCInventors: Kristopher Scott Buchanan, Johnathan Charles Sharpe
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Publication number: 20200206741Abstract: A microfluidic chip having a micro channel for processing a sample is provided. The micro channel may focus the sample by using focusing fluid and a core stream forming geometry. The core stream forming geometry may include a lateral fluid focusing component and one or more vertical fluid focusing components. A microfluidic chip may include a plurality micro channels operating in parallel on a microfluidic chip.Type: ApplicationFiled: March 9, 2020Publication date: July 2, 2020Inventors: Erin Koksal, Johnathan Charles Sharpe, Kristopher Scott Buchanan, Blair D. Morad
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Patent number: 10583439Abstract: A microfluidic chip having a micro channel for processing a sample is provided. The micro channel may focus the sample by using focusing fluid and a core stream forming geometry. The core stream forming geometry may include a lateral fluid focusing component and one or more vertical fluid focusing components. A microfluidic chip may include a plurality micro channels operating in parallel on a microfluidic chip.Type: GrantFiled: March 14, 2014Date of Patent: March 10, 2020Assignee: CYTONOME/ST, LLCInventors: Erin Koksal, Johnathan Charles Sharpe, Kristopher Scott Buchanan, Blair D. Morad
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Publication number: 20200072731Abstract: A flow cell for particle processing such as particle sorting, may be operatively engaged to a particle processing apparatus. The fluid contact surfaces of the flow cell may be fully enclosed. Further, the flow cell may encapsulate all fluid contact surfaces in the particle processing apparatus. The enclosing or encapsulation of the fluid contact surfaces insures, improves or promotes operator isolation and/or product isolation. The flow cell may employ any suitable technique for processing particles. The flow cell may be disposable and suitable for use in droplet sorting. The flow cell may include an operatively sealed sort chamber having a particle stream focusing region, an orifice, an interrogation zone and a sorting region.Type: ApplicationFiled: August 7, 2019Publication date: March 5, 2020Inventors: Johnathan Charles Sharpe, Rudolf Hulspas, Kristopher Scott Buchanan
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Patent number: 10379029Abstract: A flow cell for particle processing such as particle sorting, may be operatively engaged to a particle processing apparatus. The fluid contact surfaces of the flow cell may be fully enclosed. Further, the flow cell may encapsulate all fluid contact surfaces in the particle processing apparatus. The enclosing or encapsulation of the fluid contact surfaces insures, improves or promotes operator isolation and/or product isolation. The flow cell may employ any suitable technique for processing particles. The flow cell may be disposable and suitable for use in droplet sorting. The flow cell may include an operatively sealed sort chamber having a particle stream focusing region, an orifice, an interrogation zone and a sorting region.Type: GrantFiled: September 18, 2013Date of Patent: August 13, 2019Assignee: CYTONOME/ST, LLCInventors: Johnathan Charles Sharpe, Rudolf Hulspas, Kristopher Scott Buchanan
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Publication number: 20150129688Abstract: Microfluidic flow-through elements and methods for forming and using the same, particularly, low cost, easily sterilized, disposable microfluidic flow-through elements may include an orifice region suitable, for example, for fluid jet formation (such as in a droplet sorter or flow cell) or sample injection or hydrodynamic focusing (such as in a non-droplet flow cytometer). Laser drilling, for example laser ablation, may be used to form an orifice region extending through an orifice wall section of a base substrate. The base substrate may be unitarily-formed by injection molding a polymeric material. The orifice region may be advantageously configured to form a predetermined geometry by controlling the characteristics of the ablating beam.Type: ApplicationFiled: September 18, 2014Publication date: May 14, 2015Inventors: Kristopher Scott Buchanan, Johnathan Charles Sharpe
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Publication number: 20140318645Abstract: A microfluidic chip having a micro channel for processing a sample is provided. The micro channel may focus the sample by using focusing fluid and a core stream forming geometry. The core stream forming geometry may include a lateral fluid focusing component and one or more vertical fluid focusing components. A microfluidic chip may include a plurality micro channels operating in parallel on a microfluidic chip.Type: ApplicationFiled: March 14, 2014Publication date: October 30, 2014Applicant: CYTONOME/ST, LLCInventors: Erin Koksal, Johnathan Charles Sharpe, Kristopher Scott Buchanan, Blair D. Morad
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Publication number: 20140170697Abstract: A flow cell for particle processing such as particle sorting, may be operatively engaged to a particle processing apparatus. The fluid contact surfaces of the flow cell may be fully enclosed. Further, the flow cell may encapsulate all fluid contact surfaces in the particle processing apparatus. The enclosing or encapsulation of the fluid contact surfaces insures, improves or promotes operator isolation and/or product isolation. The flow cell may employ any suitable technique for processing particles. The flow cell may be disposable and suitable for use in droplet sorting. The flow cell may include an operatively sealed sort chamber having a particle stream focusing region, an orifice, an interrogation zone and a sorting region.Type: ApplicationFiled: September 18, 2013Publication date: June 19, 2014Applicant: CYTONOME/ST, LLCInventors: Johnathan Charles Sharpe, Rudolf Hulspas, Kristopher Scott Buchanan