Abstract: Disclosed are methods of modulating erythropoiesis with arginine vasopressin receptor 1B (AVPR1B) molecules, such as AVPR1B agonists or antagonists. In one example, a method of stimulating erythropoiesis is disclosed including administering an effective amount of an AVPR1B stimulatory molecule to a subject in need thereof, thereby stimulating erythropoiesis. Also disclosed is a method of stimulating hematopoetic stem cell (HSC) proliferation which includes administering an effective amount of an AVPR1B stimulatory molecule to a subject in need thereof, thereby stimulating HSC proliferation. A method of inhibiting HSC proliferation including administering an effective amount of an AVPR1B inhibitory molecule to a subject in need thereof, thereby inhibiting HSC proliferation is provided.

Abstract: A method performed by a packet network device for enabling forwarding of packet data traffic among a plurality of physical links from the packet network device towards a destination packet network device, e.g. in an unequal split ratio. A number of virtual links are established 504 alongside at least one physical link of the plurality of physical links. The packet data traffic is routed 506 among the physical links and the established virtual links, utilizing a shortest path routing protocol with load balancing. By establishing virtual links alongside physical links packet the data packet traffic may be routed on the total number of links, thereby achieving a more effective use of available communication resources.

Abstract: Disclosed are methods of modulating erythropoiesis with arginine vasopressin receptor 1B (AVPR1B) molecules, such as AVPR1B agonists or antagonists. In one example, a method of stimulating erythropoiesis is disclosed including administering an effective amount of an AVPR1B stimulatory molecule to a subject in need thereof, thereby stimulating erythropoiesis. Also disclosed is a method of stimulating hematopoetic stem cell (HSC) proliferation which includes administering an effective amount of an AVPR1B stimulatory molecule to a subject in need thereof, thereby stimulating HSC proliferation. A method of inhibiting HSC proliferation including administering an effective amount of an AVPR1B inhibitory molecule to a subject in need thereof, thereby inhibiting HSC proliferation is provided.

Abstract: A method performed by a packet network device for enabling forwarding of packet data traffic among a plurality of physical links from the packet network device towards a destination packet network device, e.g. in an unequal split ratio. A number of virtual links are established 504 alongside at least one physical link of the plurality of physical links. The packet data traffic is routed 506 among the physical links and the established virtual links, utilising a shortest path routing protocol with load balancing. By establishing virtual links alongside physical links packet the data packet traffic may be routed on the total number of links, thereby achieving a more effective use of available communication resources.