Patents by Inventor Krys Bankiewicz

Krys Bankiewicz has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • METHODS OF TREATING PARKINSON'S DISEASE USING VIRAL VECTORS
    Publication number: 20130101510
    Abstract: Methods of delivering viral vectors, particularly recombinant AAV virions, to the CNS are provided. Also provided are methods of treating Parkinson's Disease.
    Type: Application
    Filed: October 8, 2012
    Publication date: April 25, 2013
    Applicants: The Regents of the University of California, Genzyme Corporation
    Inventors: Krys BANKIEWICZ, Janet Cunningham
  • Methods of treating Parkinson's disease using viral vectors
    Patent number: 8309355
    Abstract: Methods of delivering viral vectors, particularly recombinant AAV virions, to the central nervous system (CNS) are provided for the treatment of CNS disorders, particularly those disorders which involve the neurotransmitter dopamine. The methods entail providing rAAV virions that comprise a transgene encoding aromatic amino acid decarboxylase (AADC) and administering the virions to the brain of a mammal using a non-manual pump.
    Type: Grant
    Filed: April 10, 2009
    Date of Patent: November 13, 2012
    Assignees: Genzyme Corporation, The Regents of the University of California
    Inventors: Krys Bankiewicz, Janet Cunningham
  • Methods of treating Parkinson's disease using viral vectors
    Publication number: 20100104537
    Abstract: Methods of delivering viral vectors, particularly recombinant AAV virions, to the CNS are provided. Also provided are methods of treating Parkinson's Disease.
    Type: Application
    Filed: April 10, 2009
    Publication date: April 29, 2010
    Applicants: Regents of the University of California, Genzyme Corporation
    Inventors: Krys Bankiewicz, Janet Cunningham
  • Methods of treating parkinson's disease using viral vectors
    Patent number: 7534613
    Abstract: Methods of delivering viral vectors, particularly recombinant AAV virions, to the CNS are provided. Also provided are methods of treating Parkinson's Disease.
    Type: Grant
    Filed: April 8, 2005
    Date of Patent: May 19, 2009
    Assignees: Genzyme Corporation, The Regents of the University of California
    Inventors: Krys Bankiewicz, Janet Cunningham
  • Methods of increasing distribution of nucleic acids
    Patent number: 7182944
    Abstract: This invention provides a method of increasing the volume of distribution of a nucleic acid encoding a therapeutic agent in a tissue in a subject during localized delivery, comprising administering to the tissue in the subject a nucleic acid encoding a therapeutic agent and a facilitating agent, whereby the inclusion of the facilitating agent increases the volume of distribution of the nucleic acid encoding a therapeutic agent in the tissue.
    Type: Grant
    Filed: April 25, 2002
    Date of Patent: February 27, 2007
    Assignee: The United States of America as represented by the Department of Health and Human Services
    Inventor: Krys Bankiewicz
  • Methods of treating central nervous system disorders using viral vectors
    Patent number: 6953575
    Abstract: Methods of delivering viral vectors, particularly recombinant AAV virions, to the CNS are provided. Also provided are methods of treating Parkinson's Disease.
    Type: Grant
    Filed: June 21, 2001
    Date of Patent: October 11, 2005
    Assignees: Avigen, Inc., The Regents of the University of California
    Inventors: Krys Bankiewicz, Janet Cunningham, Jamie L. Eberling
  • Methods of treating parkinson's disease using viral vectors
    Publication number: 20050180955
    Abstract: Methods of delivering viral vectors, particularly recombinant AAV virions, to the CNS are provided. Also provided are methods of treating Parkinson's Disease.
    Type: Application
    Filed: April 8, 2005
    Publication date: August 18, 2005
    Applicants: Regents of the University of California, Avigen, Inc.
    Inventors: Krys Bankiewicz, Janet Cunningham, Jamie Eberling
  • Methods of increasing distribution of nucleic acids
    Publication number: 20020187127
    Abstract: This invention provides a method of increasing the volume of distribution of a nucleic acid encoding a therapeutic agent in a tissue in a subject during localized delivery, comprising administering to the tissue in the subject a nucleic acid encoding a therapeutic agent and a facilitating agent, whereby the inclusion of the facilitating agent increases the volume of distribution of the nucleic acid encoding a therapeutic agent in the tissue.
    Type: Application
    Filed: April 25, 2002
    Publication date: December 12, 2002
    Inventor: Krys Bankiewicz
  • Convection-enhanced delivery of AAV vectors
    Publication number: 20020141980
    Abstract: Methods of delivering viral vectors, particularly recombinant AAV virions, to the CNS are provided. Also provided are methods of treating Parkinson's Disease.
    Type: Application
    Filed: June 21, 2001
    Publication date: October 3, 2002
    Applicant: The Regents of the University of California
    Inventors: Krys Bankiewicz, Janet Cunningham, Jamie L. Eberling
  • Methods of increasing distribution of therapeutic agents
    Publication number: 20020114780
    Abstract: The present invention provides a method of increasing the volume of distribution of a therapeutic agent in a tissue in a subject during localized delivery comprising administering to the tissue in the subject a therapeutic agent and a facilitating agent, whereby the inclusion of the facilitating agent increases the volume of distribution of the therapeutic agent in the tissue. The invention also provides a method of increasing the pharmacological activity of a therapeutic agent in a tissue in a subject during localized delivery, comprising administering to the tissue in the subject a therapeutic agent and a facilitating agent, whereby the inclusion of the facilitating agent increases the pharmacological activity of the therapeutic agent in the tissue.
    Type: Application
    Filed: November 30, 2001
    Publication date: August 22, 2002
    Inventors: Krys Bankiewicz, John Hamilton, Edward Oldfield, Heidi Phillips
  • Methods of treating Parkinson's disease using recombinant adeno-associated vector (rAAV)
    Patent number: 6309634
    Abstract: Methods of delivering viral vectors, particularly recombinant AAV virions, to the CNS are provided. Also provided are methods of treating Parkinson's Disease.
    Type: Grant
    Filed: June 26, 1999
    Date of Patent: October 30, 2001
    Assignees: Avigen, Inc., The Regents of the University of California
    Inventors: Krys Bankiewicz, Janet Cunningham