Patents by Inventor Krzysztof Grzegorzewski

Krzysztof Grzegorzewski has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Method of mobilizing pluripotential hematopoietic stem cells with IL-7
    Patent number: 5637323
    Abstract: This invention provides a method of isolating an increased number of hematopoietic stem cells from a subject comprising a) administering interleukin-7 to the subject in an amount that mobilizes the hematopoietic stem cells to the peripheral blood; and, b) isolating a population of leukocytes enriched for hematopoietic stem cells from the peripheral blood. Also provided is a method of transplanting an increased number of hematopoietic stem cells from a donor to a recipient to enhance repopulation of the recipient's hematopoietic and immune cells comprising a) administering interleukin-7 to the donor in an amount that mobilizes the hematopoietic stem cells to the peripheral blood; b) isolating a population of leukocytes enriched for hematopoietic stem cells from the donor's peripheral blood; and, c) transplanting the isolated population of leukocytes enriched for hematopoietic stem cells to the recipient, thereby enhancing the repopulation of the recipient's hematopoietic and immune cells.
    Type: Grant
    Filed: November 16, 1994
    Date of Patent: June 10, 1997
    Assignee: The United States of America as represented by the Department of Health and Human Services
    Inventors: Robert H. Wiltrout, Francis Ruscetti, Krzysztof Grzegorzewski, Jonathan Keller, Kristin L. Komschlies-McConville