Patents by Inventor Ku-Chung CHEN

Ku-Chung CHEN has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Method for treating and/or preventing myopia
    Patent number: 9670489
    Abstract: The present disclosure provides a method for treating and/or preventing myopia, including: administering an RNA interference (RNAi) to a subject, wherein the RNA interference is capable of counteracting another RNA interference, and the other RNA interference is an RNA interference capable of inhibiting an expression of PAX-6 gene, and the RNA interference capable of inhibiting an expression of PAX-6 gene comprises microRNA-328.
    Type: Grant
    Filed: March 31, 2015
    Date of Patent: June 6, 2017
    Assignee: Kaohsiung Medical University
    Inventors: Suh-Hang Juo, Ku-Chung Chen, Edward Hsi, Chung-Ling Liang
  • METHOD FOR TREATING AND/OR PREVENTING MYOPIA
    Publication number: 20160010087
    Abstract: The present disclosure provides a method for treating and/or preventing myopia, including: administering an RNA interference (RNAi) to a subject, wherein the RNA interference is capable of counteracting another RNA interference, and the other RNA interference is an RNA interference capable of inhibiting an expression of PAX-6 gene, and the RNA interference capable of inhibiting an expression of PAX-6 gene comprises microRNA-328.
    Type: Application
    Filed: March 31, 2015
    Publication date: January 14, 2016
    Inventors: Suh-Hang JUO, Ku-Chung CHEN, Edward HSI, Chung-Ling LIANG
  • Method of therapy and diagnosis of atherosclerosis
    Patent number: 8716256
    Abstract: There is provided a method of therapy of atherosclerosis, by providing microRNA let-7g, an analogue thereof or modified let-7g to organisms to inhibit the expression of lectin-like oxidized low density lipoprotein receptor-1 (LOX-1), and the binding of LOX-1 and oxidized low-density lipoprotein (oxLDL), so as to block the pathogenesis of atherosclerosis. Also, a method of diagnosis of atherosclerosis comprises determining the levels of microRNA let-7g in serum or plasma samples of organisms, in which the levels of microRNA let-7g is estimated in individuals with atherosclerosis as compared to individuals without atherosclerosis.
    Type: Grant
    Filed: June 3, 2011
    Date of Patent: May 6, 2014
    Assignee: Kaoshiung Medical University
    Inventors: Suh-Hang Juo, Ku-Chung Chen, I-Chung Hsieh, Ching-Yu Hu
  • METHOD OF THERAPY AND DIAGNOSIS OF ATHEROSCLEROSIS
    Publication number: 20140100129
    Abstract: There is provided a method of therapy of atherosclerosis, by providing microRNA let-7g, an analogue thereof or modified let-7g to organisms to inhibit the expression of lectin-like oxidized low density lipoprotein receptor-1 (LOX-1), and the binding of LOX-1 and oxidized low-density lipoprotein (oxLDL), so as to block the pathogenesis of atherosclerosis. Also, a method of diagnosis of atherosclerosis comprises determining the levels of microRNA let-7g in serum or plasma samples of organisms, in which the levels of microRNA let-7g is estimated in individuals with atherosclerosis as compared to individuals without atherosclerosis.
    Type: Application
    Filed: September 24, 2013
    Publication date: April 10, 2014
    Applicant: KAOHSIUNG MEDICAL UNIVERSITY
    Inventors: Suh-Hang JUO, Ku-Chung CHEN, I-Chung HSIEH, Ching-Yu HU