Abstract: A computer device, obtains a mammographic image of a unilateral breast. The mammographic image includes a cranial-caudal (CC)-position mammographic image and a mediolateral-oblique (MLO)-position mammographic image. The computer device invokes a breast detection model to perform a prediction of a condition of the unilateral breast according to the CC-position mammographic image and the MLO-position mammographic image. The device obtains a prediction result of the unilateral breast, and generates and outputs a detection report that includes the prediction result.

Abstract: The present disclosure belongs to the field of pharmaceutical preparations and relates to the design of a series of lipophilic derivatives by using wild-type penetrating peptide penetratin. These penetratin derivatives have a strong ability to penetrate the ocular tissues and do not cause ocular tissue toxicity. As ocular absorption enhancers, non-invasive routes could be used to achieve intraocular drug delivery and increase the ocular bioavailability of drugs. These penetratin derivatives and the ophthalmic drug delivery system constructed by them are used for eye drop administration, which could replace the intraocular injection with poor patients compliance, which greatly enhances the convenience and safety of the treatment of intraocular and fundus diseases.

Abstract: The present invention belongs to the field of pharmaceutical formulations, and relates to a composition comprising a derivative of a wild-type cell-penetrating peptide penetratin and a drug having positive charge under physiological pH conditions. The derivative of the wild-type cell-penetrating peptide penetratin is a lipophilic derivative designed by using the wild-type cell-penetrating peptide penetratin, and the molecule is positively charged as a whole under physiological pH conditions. Said composition of the present invention, as an ocular drug delivery system, can enable a drug positively charged under physiological pH conditions to be absorbed to the posterior segment of the eye by means of eye dropping, thereby providing a new route for achieving ocular delivery of a drug positively charged under physiological pH conditions.

Abstract: The present disclosure belongs to the field of pharmaceutical preparations and relates to the design of a series of lipophilic derivatives by using wild-type penetrating peptide penetratin. These penetratin derivatives have a strong ability to penetrate the ocular tissues and do not cause ocular tissue toxicity. As ocular absorption enhancers, non-invasive routes could be used to achieve intraocular drug delivery and increase the ocular bioavailability of drugs. These penetratin derivatives and the ophthalmic drug delivery system constructed by them are used for eye drop administration, which could replace the intraocular injection with poor patients compliance, which greatly enhances the convenience and safety of the treatment of intraocular and fundus diseases.

Abstract: The present disclosure belongs to the field of pharmaceutical preparations and relates to the design of a series of lipophilic derivatives by using wild-type penetrating peptide penetratin. These penetratin derivatives have a strong ability to penetrate the ocular tissues and do not cause ocular tissue toxicity. As ocular absorption enhancers, non-invasive routes could be used to achieve intraocular drug delivery and increase the ocular bioavailability of drugs. These penetratin derivatives and the ophthalmic drug delivery system constructed by them are used for eye drop administration, which could replace the intraocular injection with poor patients compliance, which greatly enhances the convenience and safety of the treatment of intraocular and fundus diseases.

Abstract: The present disclosure belongs to the field of pharmaceutical preparations and relates to the design of a series of lipophilic derivatives by using wild-type penetrating peptide penetratin. These penetratin derivatives have a strong ability to penetrate the ocular tissues and do not cause ocular tissue toxicity. As ocular absorption enhancers, non-invasive routes could be used to achieve intraocular drug delivery and increase the ocular bioavailability of drugs. These penetratin derivatives and the ophthalmic drug delivery system constructed by them are used for eye drop administration, which could replace the intraocular injection with poor patients compliance, which greatly enhances the convenience and safety of the treatment of intraocular and fundus diseases.

Abstract: The present provides a method for logging in a website hosted by a serve by multi-account and the client. The method comprises: when logging into the server using the second account, a browser: receiving, from the user, login information of the user's second account generating authority request information of the second account based on the login information of the user's second account; saving the authority request information of said second account in a local system directory of the browser separately from authority request information of a first account that has logged into said server; transmitting the authority request information of the second account, via the Internet, to the server; and after receiving, via the Internet, identification information returned from said server for identifying said second account, the browser saving said identification information in the local system directory of the browser separately from corresponding identification information of the first account.

Abstract: The present provides a method for logging in by multi-account and the client. A user uses a second account to log into a website or web page and authority request information of the second account is saved in the client separately from the authority request information of the first account that has logged into the same website or web page; after receiving identification information returned from said website or web page for identifying said second account, said identification information is saved in the client separately from the corresponding identification information of the first account. The method of the present application is simple and practical, and it can easily realize the function of logging in by multi-account. The method of the present application can be applied to various software such as a browser.