Patents by Inventor Kuang-Mei Hsu

Kuang-Mei Hsu has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 9738660
    Abstract: The present invention provides a compound of formula (I) or the salt thereof: wherein R is at least one selected from the group consisting of unsubstituted C1-4 alkyl, C1-4 alkyl substituted by C6-18 aryl or —OR1, and —C(?O)Z. The compound is a type-S protein kinase inhibitor, which binds to an ATP-binding site and a substrate-recognition site of a protein kinase simultaneously. The present invention further provides a pharmaceutical composition, which includes a compound of formula (I) or a salt and a pharmaceutically acceptable carrier thereof. The present invention further provides a use of a compound of formula (I) or a salt thereof, which is for the manufacture of a protein kinase inhibitor as a drug.
    Type: Grant
    Filed: January 16, 2015
    Date of Patent: August 22, 2017
    Assignee: National Chiao Tung University
    Inventors: Jinn-Moon Yang, Kai-Cheng Hsu, Tzu-Ying Sung, Shen Rong Lin, Yun-Ming Wang, Kuang-Mei Hsu, Hsin-Ping Lin, Wan-Chun Liu
  • Publication number: 20160096848
    Abstract: The present invention provides a compound of formula (I) or the salt thereof: wherein R is at least one selected from the group consisting of unsubstituted C1-4 alkyl, C1-4 alkyl substituted by C6-18 aryl or —OR1, and —C(?O)Z. The compound is a type-S protein kinase inhibitor, which binds to an ATP-binding site and a substrate-recognition site of a protein kinase simultaneously. The present invention further provides a pharmaceutical composition, which includes a compound of formula (I) or a salt and a pharmaceutically acceptable carrier thereof. The present invention further provides a use of a compound of formula (I) or a salt thereof, which is for the manufacture of a protein kinase inhibitor as a drug.
    Type: Application
    Filed: January 16, 2015
    Publication date: April 7, 2016
    Inventors: Jinn-Moon Yang, Kai-Cheng Hsu, Tzu-Ying Sung, Shen Rong Lin, Yun-Ming Wang, Kuang-Mei Hsu, Hsin-Ping Lin, Wan-Chun Liu
  • Patent number: 8119816
    Abstract: The present invention provides a blue laser light-absorbent substance, which is suitably used in organic photo conductor, laser optical data carrier or organic light-emitting diodes. The blue laser light-absorbent substance includes a merocyanine compound of the general formula (1) wherein n is an integer of from 0 to 3; R1 is unsubstituted or phenyl-, halogen-, ester-, siliy-substituted linear or branched alkyl group having 1 to 6 carbon atoms; R2 is unsubstituted or substituted phenyl, benzyl or naphthyl; N and R1R2 together represent aromatic-fused N-containing heterocyclic group (NR1R2); Y1 is unsubstituted or substituted alkoxy group having 1 to 8 carbon atoms; Y2 is cyano, nitro, halogen or carboxylate; or O and Y1Y2 together represent epoxy or N-containing heterocyclic hydrocarbonyl ketone (OY1Y2).
    Type: Grant
    Filed: October 13, 2006
    Date of Patent: February 21, 2012
    Assignee: Taiwan Fluoro Technology Co., Ltd.
    Inventors: Fu-Shing Wang, Kuang-Mei Hsu
  • Publication number: 20080293932
    Abstract: A phthalocyanine compound of formula (I) is provided for use in a recording layer of an optical recording media. In formula (I), M1 is a divalent transition metal, or two hydrogen atoms; X is halogen; Y is —OR1; R1 is alkyl which is unsubstituted or substituted by halogen, halogen, hydroxyl, alkoxy, alkylamino; R2 is R3 and R4 independently denote H, halogen, alkyl and alkoxyl; R5 is unsubstituted or substituted phenyl, benzyl, nathalenyl, or heterocycle; E denotes a single bond, C1-C4 alkyl, R6—C—O—C(?O), R6—O—C(?O)— or R6—S—C(?O)—; R6 is unsubstituted or substituted phenyl, benzyl, nathalenyl, heterocycle or C1-C4 alkyl; x is a number from 0 to 8; y is a number from 0 to 8; z is a number from 0 to 4; and M2 is a divalent transition metal.
    Type: Application
    Filed: July 27, 2007
    Publication date: November 27, 2008
    Applicant: TUBE SMITH TECHNOLOGY CO.,LTD.
    Inventors: Fu-Shing Wang, Kuang-Mei Hsu
  • Publication number: 20070085074
    Abstract: The present invention provides a blue laser light-absorbent substance, which is suitably used in organic photo conductor, laser optical data carrier or organic light-emitting diodes. The blue laser light-absorbent substance includes a merocyanine compound of the general formula (1) wherein n is an integer of from 0 to 3; R1 is unsubstituted or phenyl-, halogen-, ester-, siliy-substituted linear or branched alkyl group having 1 to 6 carbon atoms; R2 is unsubstituted or substituted phenyl, benzyl or naphthyl; N and R1R2 together represent aromatic-fused N-containing heterocyclic group (NR1R2); Y1 is unsubstituted or substituted alkoxy group having 1 to 8 carbon atoms; Y2 is cyano, nitro, halogen or carboxylate; or O and Y1Y2 together represent epoxy or N-containing heterocyclic hydrocarbonyl ketone (OY1Y2).
    Type: Application
    Filed: October 13, 2006
    Publication date: April 19, 2007
    Applicant: TUBE SMITH Technology CO.,LTD.
    Inventors: Fu-Shing Wang, Kuang-Mei Hsu
  • Publication number: 20030173552
    Abstract: An electrochromic solution includes a hydrazone compound as an anodic compound is disclosed.
    Type: Application
    Filed: March 12, 2003
    Publication date: September 18, 2003
    Inventors: Fu-Shing Wang, Kuang-Mei Hsu
  • Patent number: 6587251
    Abstract: An electrochromic solution includes a hydrazone compound as an anodic compound is disclosed. The hydrazone compound has a general formula (I) wherein R1, R2, R3, and R4 are individually selected from a group consisting of hydrogen, alkyl containing 5 to 20 carbon atoms, alkenyl containing 2 to 20 carbon atoms, alkynyl containing 2 to 20 carbon atoms, and aryl containing 5 to 20 atoms which are unsubstituted or optionally substituted with one or more ester, ether, aryl, amine, thioester, alkyl, alkoxy, alkene, alkyne, CN, F, Cl, Br, I and/or organometallcene functional group.
    Type: Grant
    Filed: June 24, 2002
    Date of Patent: July 1, 2003
    Assignee: Exon Science, Inc.
    Inventors: Fu-Shing Wang, Kuang-Mei Hsu
  • Patent number: 6567204
    Abstract: An electrochromic solution includes a hydrazone compound as an anodic compound is disclosed. The hydrazone compound has a general formula (I) wherein R1, R2, R3 and R4 are individually selected from a group consisting of hydrogen, alkyl containing 5 to 20 carbon atoms, alkenyl containing 2 to 20 carbon atoms, alkynyl containing 2 to 20 carbon atoms, and aryl containing 5 to 20 carbon atoms which are unsubstituted or optionally substituted with one or more ester, ether, aryl, amine, thioester, alkyl, alkoxy, alkene, alkyne, CN, F, Cl, Br, I and/or organometallcene functional group.
    Type: Grant
    Filed: September 4, 2001
    Date of Patent: May 20, 2003
    Assignee: Exon Science, Inc.
    Inventors: Fu-Shing Wang, Kuang-Mei Hsu
  • Publication number: 20030063365
    Abstract: An electrochromic solution includes a hydrazone compound as an anodic compound is disclosed.
    Type: Application
    Filed: June 24, 2002
    Publication date: April 3, 2003
    Inventors: Fu-Shing Wang, Kuang-Mei Hsu